Uroalerts Men's Health Weekly

December 30, 2025

Videos

Peer-to-Peer Clinical Conversations

Bladder-Centric Focus in BPH: Early Triage and a Five-Stage Model - Wayne Kuang

Wayne Kuang discusses his ManVsProstate initiative with Alan Wein, emphasizing bladder health preservation in BPH.

Phase 2 ALPACA Trial Evaluates Avelumab in Advanced Penile Cancer - Srikala Sridhar

Srikala Sridhar

Srikala Sridhar joins Zachary Klaassen to discuss the ALPACA trial evaluating avelumab in advanced penile cancer.

Beyond the Abstracts

Survivin and Ki-67 Immunohistochemical Expression in Penile Squamous Cell Carcinoma: Clinicopathological Features and Overall Survival - Beyond the Abstract

Testicular Cancer in Latvia: Incidence Trends and Prognostic Outcomes Across a 23-Year Study - Beyond the Abstract

Articles

Editor Selected Abstracts and Commentaries

Male Infertility

Seminal Plasma Exosomal miRNA Profiling Reveals hsa-miR-7-5p as a Key Regulator of Sperm Motility in Asthenozoospermia.

Preimplantation genetic testing for aneuploidy versus no genetic testing in couples undergoing intracytoplasmic sperm injection for severe male infertility: multicentre, open label, randomised controlled trial.

Analysis of AZF microdeletion, chromosome karyotypes, and sex hormone levels in 3060 male infertility: A retrospective study in Ningxia of China.

The Use of Testicular Sperm Extraction in Male Infertility Patients Without Azoospermia.

The road to restore male fertility using in vitro-derived germ cells.

Peyronie's Disease

Repeatability in measuring curvature in Peyronie's disease.

Differential genetic expression in the tunica albuginea tissue of patients with Peyronie's disease.

Effectiveness of hyaluronic acid in the treatment of Peyronie's disease in the light of the European Urology Guidelines: the real-world experience.

Prostatitis

Efficacy of flower pollen extract with vitamins in improving urinary and sexual function in patients with chronic prostatitis: a retrospective study.

Erectile Dysfunction

Erectile Dysfunction: Expert Panel Recommendations for Evaluation and Management in the United Arab Emirates.

BPH - Benign Prostatic Enlargement

Holmium Laser Enucleation of the Prostate vs Multi-Port Robotic-Assisted Simple Prostatectomy vs Single-Port Robotic-Assisted Simple Prostatectomy: A Single-Center Experience.

Financial burden of prolonged urinary retention in patients awaiting holmium laser enucleation of the prostate in the Quebec healthcare system: A retrospective cohort study.

Prostatic enucleation vs. photoselective vaporization of prostate vs. simple prostatectomy: performance, functional results and complications.

Rezūm therapy: Outcomes of symptom relief and quality of life in benign prostatic obstruction with three-year followup.

Penile & Urethral Cancers

Impact of the Area Deprivation Index on stage at diagnosis in penile squamous cell carcinoma: A statewide cohort analysis.

Efficacy and safety of tislelizumab combined with chemotherapy for locally advanced penile cancer: a prospective, single-arm clinical study.

Comparison of efficacy and prognosis between neoadjuvant chemotherapy and adjuvant chemotherapy in penile cancer patients with regional lymph node metastasis.

Testicular Cancer

Guideline of guidelines: management of small testicular masses.

Prostate Cancer

Whole-Slide Telepathology Grading of Prostate Cancer in Biopsies Using ISUP Criteria: Inter- and Intra-Observer Concordance and Implications for Active Surveillance.

Extraperitoneal robot-assisted radical prostatectomy with the Hugo™ RAS system: 100 consecutive cases, 1-year follow-up and surgical learning curve evaluation.

Geometric evaluation of a deep learning method for segmentation of urinary OARs on magnetic resonance imaging for prostate cancer radiotherapy.

Molecular alteration profiles characterize intraductal carcinoma of the prostate.

Adiponectin receptor agonist, AdipoRon, reduces the growth of prostate cancer cells and patient-derived organoids.

Real-World Treatment Outcomes in Patients With Ga68-PSMA-PET Positive Metastatic Hormone-Sensitive Prostate Cancer With or Without Conventional Imaging Correlates.

Dyadic Associations of Physical Activity, Diet Quality, and Body Mass Index in Black Prostate Cancer Survivors and their Spouses: An Actor-Partner Interdependence Model Analysis.

Socioeconomic Status and Prostate-specific Antigen Testing: A Population-based Cohort Study Comparing Organised and Opportunistic Prostate Cancer Testing.

Radical prostatectomy outcomes in patients with PI-RADS 5 lesions and favorable prostate cancer.

Spatial immune profiling of bone-metastatic castration-resistant prostate cancer reveals radium-223 immunomodulates the bone-tumor microenvironment.

Barriers and facilitators to prostate cancer healthcare in Black men in the UK: from diagnosis to survivorship.

Study design and methodologies for the men moving forward lifestyle intervention trial with black prostate cancer survivors.

Does the Accuracy of Prostate-specific Antigen Density in Identifying Clinically Significant Prostate Cancer Change with Prostate Volume?

Quantifying partial pathological response rate in prostate cancer patients who underwent neoadjuvant chemotherapy using a novel morphometric approach.

Clonal evolution and transcriptional plasticity shape metastatic dissemination routes in prostate cancer.

Development and Validation of a Multimodal Artificial Intelligence-derived Digital Pathology-based Biomarker Predicting Metastasis Among Patients with Biochemical Recurrence After Radical Prostatectomy in NRG/RTOG Trials.

Impact of androgen receptor pathway inhibitors on cognitive function in older adults treated for metastatic prostate cancer.

Evaluating Differential Metabolic Profiles by Prostate Cancer Risk Among Prostate Cancer Patients.

Canadian Prostate Cancer Trends in the Context of PSA Screening Guideline Changes.

Integration of Darolutamide in the Treatment Landscape for Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis of Efficacy and Safety.

Pre-PROTO-PRIME: stereotactic body proton therapy to the prostate and pelvic nodes for high-risk and node-positive prostate cancer - feasibility, acute toxicity and dosimetric insights.

Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate cancer.

Western Dietary Pattern, Prudent Dietary Pattern, and Cancer-Specific Quality of Life in Prostate Cancer Survivors in the Health Professionals Follow-up Study.

Initial pain score during viscous lidocaine instillation and clinical characteristics as predictors of overall pain in fusion prostate biopsy.

CDC7 is a targetable regulator of advanced prostate cancer.

Primary Noncontrast Magnetic Resonance Imaging for Prostate Cancer Screening: A Randomized Clinical Trial (PROSA).

Genomic variation in symptom expression in castrate-resistant prostate cancer.

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