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Transformative Evidence
mCRPC
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PEACE-3 Trial
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The RALU Study: Treatment Considerations in the First Line Setting of mCRPC
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Leslie Ballas, MD
Kidney Cancer
Advanced Kidney Cancer
Pedro Barata, MD, MSc
Endourology
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Jaime Landman, MD
Prostate Cancer
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Matthew R. Cooperberg, MD, MPH
Decipher® Genomic Classifier
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Phillip Koo, MD
mHSPC
Neeraj Agarwal, FASCO, MD
nmCRPC
Zachary Klaassen, MD, MSc
mCRPC Treatment
A. Oliver Sartor, MD
mCRPC with Bone Metastasis
PSMA-Targeted Therapy
Advanced Prostate Cancer
Zachary Klaassen, MD, MSc
Disparities: Social Determinants of Health
Disparities: Social Determinants of Health
Samuel L. Washington III, MD, MAS
Translational Prostate Cancer
Translational Science in Prostate Cancer
Andrea Miyahira, Ph.D
Women in Science
Andrea Miyahira, Ph.D
Upper Tract Urothelial Carcinoma
Upper Tract Urothelial Carcinoma
Sam S. Chang, MD, MBA
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Alan J. Wein, MD, PhD (hon.)
Urologic Catheters - CAUTI Challenges
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From the Editor
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November 18, 2025
Videos
Peer-to-Peer Clinical Conversations
Optimizing Advanced Prostate Cancer Care: Balancing Intensification and Overtreatment - Gerhardt Attard
Gerhardt Attard
Gerhardt Attard joins Zachary Klaassen to discuss advances in advanced prostate cancer treatment emerging from ESMO.
View
Preoperative Urinary Retention and Its Effect on HoLEP Surgery Outcomes - Diana Lopategui
Alan Wein hosts Diana Lopategui to present a retrospective database analysis examining whether chronic urinary retention severity impacts HoLEP outcomes.
View
Beyond the Abstracts
First Use of the FloStent™ for Catheter-Dependent Urinary Retention Secondary to BPH: Additional Results from the RAPID I Study - Beyond the Abstract
Role of Retroperitoneal Lymph Node Dissection in Clinical Stage IIA/B Seminoma: Recommendations from the European Association of Urology Guidelines Panel on Testicular Cancer - Beyond the Abstract
Articles
Editor Selected Abstracts and Commentaries
Androgen Deficiency
"We Are Too Young to Worry": Late-Midlife Adults' Voices on Sexual Changes, Distress, and Help-Seeking Behaviors.
Male Infertility
SPG360° and SpermoMAP: a functional and stratified interpretation model for human semen analysis in frontline fertility care.
Quasi-randomized pilot clinical trial comparing the use of annexin columns in patients with abnormal sperm FISH undergoing IVF techniques.
Are infertile men at a higher risk of morbidity and early mortality?
Sperm rDNA Copy Number and Methylation Are Associated with Male-Factor Infertility.
Erectile Dysfunction
Association between erectile dysfunction and relative fat mass in adult men in the United States.
Erectile dysfunction increases the risk of stroke: evidence from NHANES and Mendelian randomization analysis.
Association between social determinants of health and erectile dysfunction: insights from a nationally representative US sample.
Cutting Costs, Not Care: New Models for Affordable Men's Health Medications.
BPH - Benign Prostatic Enlargement
Prostatic Surgery With Preservation of the Supramonticular Tissue Versus Standard Surgery for Benign Prostatic Hyperplasia: A Systematic Review.
Impact of Preoperative Catheter Duration on Perioperative Safety and Functional Outcomes Following Holmium Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia: Results From a Single-Center Series.
Tranexamic acid and hematuria outcomes following aquablation for benign prostatic hyperplasia.
Aquablation for Benign Prostatic Hyperplasia: A Prospective Study with Comparative Analysis of Transurethral Resection of the Prostate and Holmium Laser Enucleation.
Standardized Technique for Prostatic Artery Embolization: A Delphi Consensus Study on Optimized Methods and Emerging Concepts.
First Use of the FloStent™ for Catheter-Dependent Urinary Retention Secondary to BPH: Additional Results from the RAPID I Study - Beyond the Abstract
Machine Learning Models to Predict Postoperative Incontinence after Endoscopic Enucleation of the Prostate for Benign Prostatic Hyperplasia: An EAU-Endourology Study - Beyond the Abstract
Penile & Urethral Cancers
Personalized systemic therapy of penile cancer: molecular targets and new therapeutic horizons.
Tissue Factor Expression in Penile Squamous Cell Carcinoma: A Potential Marker of HPV-Independent Disease.
Testicular Cancer
Comparative efficacy and safety of robotic-assisted versus open retroperitoneal lymph node dissection in testicular cancer management: a systematic review and meta-analysis.
Improved quality of care for testicular germ cell cancer patients by the implementation of an interdisciplinary testis cancer clinic.
Primary Retroperitoneal Lymph Node Dissection in Marker Positive Clinical Stage II Non-Seminomatous Germ Cell Tumours.
Role of Retroperitoneal Lymph Node Dissection in Clinical Stage IIA/B Seminoma: Recommendations from the European Association of Urology Guidelines Panel on Testicular Cancer - Beyond the Abstract
Prostate Cancer
Long-Term Follow-Up of Neoadjuvant Enzalutamide Plus Androgen Deprivation Therapy in Localized Prostate Cancer: A Secondary Analysis of a Neoadjuvant Feasibility Trial.
The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 68Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer: Safety and diagnostic accuracy compared to histopathology and their impact on patient management.
Combined DNA-PK and PARP Inhibition as a Therapeutic Strategy in BRCA-Mutated Prostate Cancer: An in Vitro Pilot Study.
68Ga-PSMA-11 in Staging of Unfavorable Intermediate- and High-Risk Prostate Cancer Reduces Indication for Noncurative Prostatectomy: A Prospective, Multicenter, International IAEA Study.
Abiraterone-Associated Renal Damage in Patients with Advanced Prostate Cancer as a Risk Factor for Mortality and Chronic Kidney Disease.
New Prostate Cancer Guideline: Is Biopsy of PI-RADS 3 Lesions Meaningful? The Role of Multiparametric MRI-Ultrasound Fusion Biopsy in Detecting Clinically Significant Prostate Cancer.
A mixed-methods evaluation of a peer-led, co-produced, asset-based intervention for early diagnosis of prostate cancer for Black men: the PROCAN-B study.
Design of debunking the frailty-sarcopenia-ADT axis in metastatic prostate cancer with multicomponent exercise: the FIERCE trial protocol.
Clinical Grade Interpretable Artificial Intelligence Tool for Automated Detection of Lymph Node Metastasis in Prostate Cancer.
Predicting PSA50 response to [Formula: see text]Lu-PSMA therapy using machine learning and automated total tumor volume.
MRI-Fusion Biopsy Era: The Role of Perineural Invasion in Low-Risk Prostate Cancer - Beyond the Abstract
High-Dose-Rate Brachytherapy for Salvage Treatment of Prostate Cancer Recurrence Post-Prostatectomy and Radiotherapy: A Multicenter Retrospective Analysis (HDR-REPOPRA) by UroGEC - Beyond the Abstract
Quantification of Prostate Cancer Gleason Pattern 4 to Predict Oncological Outcome - Beyond the Abstract
The Role of Liquid Biopsy in the Management of Patients with Genitourinary Malignancies.
ONECUT2: A Validated Drug Target and Lineage Plasticity Driver in Prostate Cancer and Other Malignancies.
Treatment Preferences among Patients with Hormone-Sensitive Prostate Cancer in France, Spain, China, South Korea, and Japan: A Discrete-Choice Experiment.
Value of Additional Systematic Cores During Magnetic Resonance Imaging-guided Targeted Biopsy in Prostate Cancer Screening for Young Men: Results from the PROBASE Trial.
PARP Inhibitors in Metastatic Castration-resistant Prostate Cancer: Rationale, Mechanisms, and Clinical Applications.
177Lu-Prostate-Specific Membrane Antigen Neoadjuvant to Stereotactic Ablative Radiotherapy for Oligorecurrent Prostate Cancer (LUNAR): An Open-Label, Randomized, Controlled, Phase II Study.
Diet-metabolism-transcription axis modulates the sensitivity to CDK4/6 inhibitors through RB1 in prostate cancer.
Chromatin remodeling restrains oncogenic functions in prostate cancer.
Thyroid hormone receptor beta signaling is a targetable driver of prostate cancer growth.
A PHF19-YTHDC1 condensate switches EZH2-mediated gene suppression to activation for prostate cancer progression.
Stockholm3 Versus Prostate-specific Antigen in Prostate Cancer Screening: 9-year Outcomes Demonstrating Improved Detection of Aggressive Cancers and Reduced Overdiagnosis from the STHLM3 Trial.
Therapeutic targeting of prostate-specific membrane antigen could limit its potential as benchmark imaging.
Collagen-binding IL-12-armoured STEAP1 CAR-T cells reduce toxicity and treat prostate cancer in mouse models.
PRDM16 Regulates Prostate Cancer Cell Dormancy and Prevents Bone Metastatic Outgrowth.
RCC2 and CD24 cooperate to modulate prostate cancer progression through vimentin ubiquitination and β-catenin activation.
Protein disulfide isomerases regulate androgen receptor stability and promote prostate cancer cell growth and survival.
Analysis of cfDNA fragmentomics metrics and commercial targeted sequencing panels.
The Pelvic Rosetta Classification Project: An Interdisciplinary Proposal for a Lymph Node Map of the Pelvis in Prostate Cancer.
Rechallenge and Extended [177Lu]Lu-PSMA Therapy in Metastatic Prostate Cancer.
Evaluating Clinical Tools to Monitor Cardiovascular Risk in Men With Prostate Cancer Receiving Hormone Therapy.
Effect of prior HoLEP procedure on multiparametric MRI accuracy in detection of prostate cancer.
Rising metastatic prostate cancer rates but narrowing racial gap.
HLA Class I Expression Shapes the Tumor Immune Microenvironment and Influences Prognosis in Prostate Cancer - Beyond the Abstract
Truqap Combination in PTEN-Deficient Metastatic Hormone-Sensitive Prostate Cancer Demonstrated Statistically Significant and Clinically Meaningful Improvement in Radiographic Progression-Free Survival in CAPItello-281 Phase III Trial
New USC Study Identifies Key Genes Linked to Aggressive Prostate Cancer in People of African Descent
Integrating Pathogenic Variants, Polygenic Risk Score, and Family History for Prostate Cancer Risk Estimation in Men of African Ancestry.
Factors Associated with Early Detection of Clinically Significant Prostate Cancer After a Negative MRI-Informed Biopsy.
Darolutamide plus androgen-deprivation therapy in high-risk biochemical recurrence of prostate cancer (ARASTEP).
Virtual versus in-person sexual rehabilitation for prostate cancer survivors: a retrospective cohort study comparing the Prostate Cancer Rehabilitation Clinic (PCRC) and the True North Sexual Health and Rehabilitation eClinic (SHAReClinic).
Emerging evidence for sequencing and combining PSMA-based therapies in prostate cancer.
Prostate Cancer, Version 3.2026, NCCN Clinical Practice Guidelines In Oncology.
Plasma Epigenomic Profiling Reveals Treatment-Emergent Squamous Transformation in Prostate Cancer - Beyond the Abstract
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