Uroalerts Men's Health Weekly

October 07, 2025

Videos

Peer-to-Peer Clinical Conversations

Randomized Trial of NeuroSAFE Technique in Radical Prostatectomy for Erectile Function - Eoin Dinneen & Ricardo Almeida-Magana

Eoin Dinneen

Ricardo Almeida-Magana and Eoin Dinneen share NeuroSAFE PROOF trial results with Zachary Klaassen, presenting the first randomized controlled trial demonstrating improved erectile function after radical prostatectomy.

Cholesterol Metabolism Pathway in Prostate Cancer Models - Daniel Frigo

Daniel Frigo

Daniel Frigo shares metabolism research with Andrea Miyahira, revealing how CAMKK2-CREB signaling drives castration-resistant prostate cancer through cholesterol metabolism regulation.

Beyond the Abstracts

Identification of Missense DMC1 Variants in Males with Non-Obstructive Azoospermia - Beyond the Abstract

Lymphovascular Invasion Predicts Cancer-Specific Mortality in Penile Localized Squamous Cell Carcinoma - Beyond the Abstract

Conference Coverage

ASCO 2025: An Open Label Randomized Non-Inferiority Trial Comparing Adjuvant Platinum + Paclitaxel to Platinum + 5-FU After Curative Resection in High-Risk Penile Carcinoma

AUA 2025: Predictive Value of Penile Doppler Ultrasound Impairments

AUA 2025: Second Opinion Cases: Penile Fracture

EAU 2025: Testis Cancer: Micro RNA

EAU 2025: Penile Cancer: HPV status

Articles

Editor Selected Abstracts and Commentaries

Androgen Deficiency

Discovering a new paradigm: Gut microbiota as a central modulator of sexual health.

Male Infertility

Andrological profile of infertile men with necrozoospermia (phenotypical features and etiologies): retrospective analysis of a cohort of more than 300 patients.

Association of male sleep quality with semen parameters and pregnancy outcomes in infertile couple.

Male Infertility Management: A Critical Appraisal of Clinical Practice Guidelines With the AGREE II Instrument.

Managing obesity-related male infertility: insights from weight loss intervention.

Identification of Missense DMC1 Variants in Males with Non-Obstructive Azoospermia - Beyond the Abstract

Erectile Dysfunction

Exploring the Causal Association Between Erectile Dysfunction and Brain Cortical Structure: Insight from a Bidirectional Mendelian Randomization Study and Cross-Sectional Neuroimaging Study.

Use of Secondary Reflectors for Enhanced ESWT Treatment of the Penis.

Penile trauma management in absence of fracture: Long-term outcomes.

Serum uric acid and male erectile dysfunction: A Mendelian randomization study.

BPH - Benign Prostatic Enlargement

Association between metabolic syndrome and risk of benign prostatic hyperplasia: a prospective cohort study of 163 975 participants.

Learning curve analysis of transurethral thulium fiber laser enucleation of the prostate with preserving urethral Mucosa at the prostatic apex.

Sexual safety and efficacy of a pollen extract and teupolioside-based supplement in men with benign prostatic hyperplasia: a prospective observational study.

Benign prostatic hyperplasia and risk of urological cancers: a prospective cohort study based on the UK biobank.

Carbon-Ion Radiotherapy for Prostate Cancer in Patients with a History of Surgery for Benign Prostatic Hyperplasia.

Penile & Urethral Cancers

An update on the pharmacotherapy of penile cancer.

Testicular Cancer

Stimulated Raman histology as a novel method for rapid pathologic examination of unprocessed, fresh testicular biopsies to determine seminoma.

Testicular cancer in Latvia: incidence trends and prognostic outcomes across a 23-year study.

MicroRNA as a Liquid Biomarker to Detect Malignancy in Small Testicular Masses.

Prostate Cancer

Transcriptomic Profiling of the Tumor Immune Microenvironment Reveals Prognostic Markers in mCRPC Patients Treated with LuPSMA Therapy.

Association of Travel Burden with Definitive Prostate Cancer Treatment: A United States Registry Cohort Study.

Is it time for Canada to revisit its approach to prostate cancer screening?

Real-world clinical outcomes of oligometastatic prostate cancer using SBRT: An Australian experience.

The impact of short-term non-steroidal androgen antagonist therapy on PSMA expression and tumor cellularity studied with dynamic [68Ga]Ga-PSMA-11 PET/MR in hormone-sensitive prostate cancer patients, a preliminary longitudinal prospective study.

Pathogenic variants reveal candidate genes for prostate cancer germline testing for men of African ancestry.

The future of androgen receptor targeting in prostate cancer: third-generation inhibitors and beyond.

Theranostics 2.0: Target-Driven, Artificial Intelligence-Enabled Cancer Therapy Across Tumor Types - Beyond the Abstract

Clinical and Transcriptomic Characterization of Metastatic Hormone-Sensitive Prostate Cancer Patients with Low PTEN Expression - Beyond the Abstract

Impact of Metastasis-Directed Therapy Guided by Different PET/CT Radiotracers on Distant and Local Disease Control in Oligorecurrent Hormone-sensitive Prostate Cancer: A Secondary Analysis of the PRECISE-MDT Study - Beyond the Abstract

Prostate Radiotherapy in Patients with Metastatic Hormone-Sensitive Prostate Cancer: A Systematic Review and Meta-Analysis of Randomised Controlled Trials - Beyond the Abstract

Cardiovascular disease and diagnosis of advanced prostate cancer.

Automated machine learning for prostate cancer detection and Gleason score prediction using T2WI: a diagnostic multi-center study.

Cabazitaxel Versus Abiraterone or Enzalutamide for Poor-prognosis Metastatic Castration-resistant Prostate Cancer After Docetaxel: A Phase 2 Trial with a Circulating Tumor DNA Analysis.

Stereotactic Intensity-modulated Radiotherapy After Radical Prostatectomy (SCIMITAR): 4-Year Outcomes of a Phase 2 Clinical Trial.

Next-Generation Nerve-Sparing Techniques in Robotic Radical Prostatectomy: A Contemporary Review.

MiraDx Announces the Commercial Availability of PROSTOX™ ultra for Prediction of Risk of Late Genitourinary Toxicity in Prostate Cancer Patients Considering Radiation Therapy

The role of PSMA PET/CT in staging patients with intermediate-risk prostate cancer.

Robotic-Assisted Radical Prostatectomy in the Elderly Patient-A Study of Functional, Surgical, and Oncological Outcomes in an Australian Cohort.

Evolving Global Trends in Prostate Cancer: Disparities Across Income Levels and Geographic Regions (1990-2019).

Development and validation of the PREVES-HOR Questionnaire: a patient-reported measure of hormone-therapy-related quality of life in prostate-cancer patients undergoing androgen-deprivation therapy.

First-Line [177Lu]Lu-PSMA-617 Therapy Without ADT, Chemotherapy, or Local Therapy for Metastatic Hormone-Sensitive Prostate Cancer.

Safety of the Combination of External Beam Radiotherapy with 177Lu-PSMA-617 in Patients with Metastatic Castration-Resistant Prostate Cancer.

Stage Migration on Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography in Comparison to Conventional Imaging in Patients with High-risk Prostate Cancer Referred for Radiation Therapy: Results from the Phase 2/3 THUNDER Tria

Prognostic Significance of the Cytoplasmic Expression of UDP-glucuronosyltransferase 2B17 in Localized Prostate Cancer: Insights from the Canadian Prostate Cancer Biomarker Network and PROCURE Multi-institutional Cohorts.

The Comparative Toxicity of Focal Ablation vs. IMRT for Prostate Cancer.

Detection of Clinically Significant Prostate Cancer Using Micro-Ultrasound Versus MRI/Ultrasound Fusion Biopsy: A Propensity-Weighted Comparative Study.

Diagnostic accuracy of biparametric vs. multiparametric MRI for clinically significant prostate cancer.

Adjustable TransObturator Male System (ATOMS) After Radiotherapy: Is Timing Everything? A Single-Center Experience.

Preclinical Evaluation of [212Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen-Targeted α-Therapy for Prostate Cancer.

Prognostic Value of AI-Assisted Lesion Tracking on End-of-Treatment PSMA PET in mCRPC Patients Treated with 177Lu-PSMA: A Retrospective, Single-Center Study.

Treatment of Biochemical Recurrence after Primary Therapy with Curative Intent - Beyond the Abstract

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