Uroalerts Men's Health Weekly

September 30, 2025

Videos

Peer-to-Peer Clinical Conversations

When a Health Economist Becomes a Cancer Patient - David Dranove

David Dranove

Daniel Joyce speaks with David Dranove, a healthcare economics professor who experienced bladder cancer firsthand.

Minimally Invasive Approaches in the Treatment of BPH: Ready to Replace TURP? - Claus Roehrborn

Claus Roehrorn

Claus Roehrborn provides a state of the art review on contemporary management of male lower urinary tract symptoms and BPH.

Beyond the Abstracts

Iron Biomarkers in Men with Infertility Are Associated with Sperm DNA Hydroxymethylation and Cumulative Live Birth Rates: A Prospective Study - Beyond the Abstract

Beyond Germ Cell Tumors: Focus on Leydig Cell Neoplasms from a Single-Center Experience - Beyond the Abstract

Conference Coverage

ASCO 2025: An Open Label Randomized Non-Inferiority Trial Comparing Adjuvant Platinum + Paclitaxel to Platinum + 5-FU After Curative Resection in High-Risk Penile Carcinoma

EAU 2025: Testis Cancer: Micro RNA

EAU 2025: Penile Cancer: HPV status

Articles

Editor Selected Abstracts and Commentaries

Male Infertility

The role of sperm DNA fragmentation in reproduction: a SWOT analysis.

Sperm DNA methylation landscape in infertile men with clinical varicocele: unravelling the treatment effect.

Glycerol Kinase 2 as a Metabolic Sentinel for Human Sperm Motility and Male Fertility.

Sperm vacuolization and mitochondrial activity in raw versus prepared semen: impact on embryological outcomes

Iron Biomarkers in Men with Infertility Are Associated with Sperm DNA Hydroxymethylation and Cumulative Live Birth Rates: A Prospective Study - Beyond the Abstract

Peyronie's Disease

Erectile dysfunction in patients with Peyronie's disease treated with different grafts: a systematic review.

Erectile Dysfunction

The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe?

Predictors of intraoperative complications in men undergoing inflatable penile prosthesis placement.

The association between lipid accumulation product and erectile dysfunction in hypertensive and diabetic men: a cross-sectional analysis of NHANES 2001-2004.

BPH - Benign Prostatic Enlargement

Impact of Prostatic Urethral Lift and Water Vapor Energy Therapy on Bladder Outlet Obstruction in Elderly or Comorbid Patients With Benign Prostatic Hyperplasia in Real-World Clinical Practice.

First-in-US Pilot Study of Aquablation in Ambulatory Surgery Centers: Clinical Outcomes and Economic Feasibility.

Relevance of STIM/Orai Calcium Entry System Hyperactivation in Human Prostate Contractility in Benign Prostate Hyperplasia.

Endoscopic simulators in benign prostatic hyperplasia surgical training: a scoping review.

Transurethral resection of the prostate in the extreme elderly (≥ 85 years): treatment success, morbidity and survival.

Penile & Urethral Cancers

A Rare Genital Concomitant Presentation of Extracavitary Primary Effusion Lymphoma and Squamous Cell Carcinoma.

Evaluating the Evolving Treatment Landscape of Systemic Therapies in Penile Cancer.

Psychometric properties and content of instruments for assessing penile cancer patients' quality of life: A systematic review.

Testicular Cancer

"We're the silent people in the situation": a qualitative examination of the lived experiences of young partners of men diagnosed with testicular cancer.

Molecular Features and Actionable Gene Targets of Testicular Germ Cell Tumors in a Real-World Setting.

Longitudinal Evaluation of Circulating Tumor DNA as a Prognostic Biomarker to Detect Molecular Residual Disease in Germ Cell Tumors.

Exercise, diet and psychological support for patients with testicular cancer.

Beyond Germ Cell Tumors: Focus on Leydig Cell Neoplasms from a Single-Center Experience - Beyond the Abstract

Post-prostatectomy incontinence

Preoperative MRI Predictors for Post-Prostatectomy Urinary Incontinence.

Prostate Cancer

Association of Weight Loss and BMI on PSA Levels and Overall Survival in Veterans With Metastatic Castrate-Resistant Prostate Cancer.

Targeting FOXA1 and FOXA2 disrupts the lineage-specific oncogenic output program in prostate cancer.

Theranostic Potential of a New 64Cu-Labeled NOTA-R954 Peptide Conjugate for Kinin B1R Expressing Prostate Cancer.

Exploring the Intestinal Microbiota Profile in Prostate Cancer Patients and Healthy Controls.

CYR61 Expression Is Induced by IGF1 and Promotes the Proliferation of Prostate Cancer Cells Through the PI3/AKT Signaling Pathway.

Reappraisal of Neuroendocrine Tumor Classification of the Prostate Gland: Translating Molecular Insights into Clinical Practice.

Hypofractionated Dose Escalation Radiotherapy for High-Risk Prostate Cancer: the survival analysis of the Prostate Cancer Study-5 (PCS-5), a GROUQ-led phase III trial.

Latest Advancements and Future Directions in Prostate Cancer Surgery: Reducing Invasiveness and Expanding Indications.

Evolution of Potentially Actionable Genomic Alterations in Advanced Prostate Cancer: A Real-World Analysis of Serial Circulating Tumor DNA Testing.

Application of the STRATCANS Criteria to the MUSIC Prostate Cancer Active Surveillance Cohort: A Step Towards Risk-Stratified Active Surveillance.

The comeback of orchiectomy in advanced prostate cancer- is that feasible?

Addition of androgen-receptor pathway inhibitors to standard of care in metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis.

Impaired Mitochondrial Metabolism Is a Critical Cancer Vulnerability for MYC Inhibitors

Multiparametric MRI combined with PSA density as a noninvasive rule-out strategy in active surveillance for prostate cancer.

Extracellular Vesicles in Serum Carry Trop2 Protein as a Potential Molecular Indicator in Prostate Cancer.

Impact of PARP Inhibitors on Health-related Quality of Life in Patients with Metastatic Castration-resistant Prostate Cancer: A Systematic Review and Meta-analysis.

177Lu-vipivotide tetraxetan (PSMA-617) vs cabazitaxel in metastatic castration-resistant prostate cancer: a real-world analysis using the TriNetX database.

Robot-Assisted Salvage Prostatectomy: External Validation of the EAU Selection Criteria and Identification of the Optimal Candidate: A Junior ERUS/YAU Collaborative Study.

National and Location-Specific Medicare Physician Fee Reimbursement Trends in Urologic Oncology From 2002 to 2024.

Lantheus and GE HealthCare Announce Exclusive Licensing Agreement for Prostate Cancer Imaging Agent PYLARIFY® (Piflufolastat F 18) in Japan

First evidence of Retzius-sparing robot-assisted radical prostatectomy with the Versius robotic surgical system.

Perioperative outcomes comparing the DaVinci 5 with DaVinci Xi in patients undergoing robotic-assisted radical prostatectomy.

Adverse events during radical prostatectomy and their association with recurrence and death.

Association between prostate radiotherapy and survival among patients with metastatic prostate cancer by extent of disease burden.

177Lu-PSMA vs. cabazitaxel in patients with castration-resistant prostate cancer: Real-world efficacy and safety data from the ARON-3 study.

Managing Robotic Radical Prostatectomy in Men with Penile Prosthesis: Surgical Tech-nique, Outcomes, and Literature Review.

Review of Transperineal and Transrectal Prostate Biopsy Outcomes - Beyond the Abstract

Urinary tract events after radical radiotherapy (RT) for prostate cancer according to pre-RT International Prostate Symptom Score.

Prognostic Value of Comprehensive Analysis of Metastatic Prostate Tumor Changes from First to Last [177Lu]Lu-PSMA Therapy Injections Through Serial High-Speed Whole-Body 360° Cadmium-Zinc-Telluride SPECT.

Should We Embark on "EMBARK"? Reassessing the Role of Radiotherapy and Androgen Receptor Pathway Inhibitors in the Era of Next-generation Imaging.

Using patient-reported outcomes from the PROCLAIM trial to assess the impact of universal germline genetic testing for prostate cancer patients.

Emerging tools for the early detection of prostate cancer.

Stage-Standardized and Stage-Specific Survival Among Men with Prostate Cancer in the Nordic Countries 2004-16: The NORDCAN Survival Studies - Beyond the Abstract

Magnetic Resonance Guided Stereotactic Reirradiation for Locally Recurrent Prostate Cancers: Long-Term Results from a Prospective Registry Study - Beyond the Abstract

Updated Results of MR-Assisted Focal Salvage HDR Prostate Brachytherapy: A Prospective Study - Beyond the Abstract

BRCA2 Reversion Mutation-Independent Resistance to PARP Inhibition Through Impaired DNA Prereplication Complex Function - Beyond the Abstract

Determining Optimal Patient Selection for High-intensity Focused Ultrasound for Prostate Cancer - Beyond the Abstract

Clinical Trial Protocol for prePSMA: A Multicenter, Randomized, Noninferiority Trial of Preoperative Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography as Triage for Extended Pelvic Lymph Node - Beyond the Abstract

Role of the Stockholm3 Test in Guiding Confirmation Biopsy Decisions for Patients with Prostate Cancer on Active Surveillance - Beyond the Abstract

BCL2 Drives Castration Resistance in Castration-Sensitive Prostate Cancer by Orchestrating Reciprocal Crosstalk Between Oncogenic Pathways - Beyond the Abstract

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