Uroalerts Men's Health Weekly

July 28, 2025

Videos

Peer-to-Peer Clinical Conversations

Male Pelvic Pain Treatment: Beyond the Misconception of Prostatitis - Jeannette Potts

Jeannette Potts

Jeannette Potts discusses her mission to eliminate the use of the term "prostatitis" in diagnosing pelvic pain in men.

CAN-2409 + Radiation Improves Disease-Free Survival in Prostate Cancer Patients - Angela Jia

Angela Jia

Leslie Ballas is joined by Angela Jia to discuss the phase 3 trial of CAN-2409, an oncolytic virus therapy for localized prostate cancer.

Beyond the Abstracts

Inhibition of Phosphodiesterases 1 and 4 Prevents Myofibroblast Transformation in Peyronie's Disease - Beyond the Abstract

Ejaculation-Sparing Enucleation of the Prostate with Thulium: Yag Laser (ES-ThuLEP) Versus Thulium Fiber Laser (ES-ThuFLEP): Outcomes on Sexual Function - Beyond the Abstract

Conference Coverage

SNMMI 2025: The Clinical Value of the PROSTest to Detect Biochemical Recurrence in Prostate Cancer

ASCO 2025: A Multicenter, Randomized, Phase 2, Investigator-Initiated ETCTN Trial of Olaparib + Radium-223 vs. Radium-223 in Men with Castration-Resistant Prostate Cancer (CRPC) with Bone Metastases (BM) (COMRADE): Initial Efficacy and Biomarker Analysis

Articles

Editor Selected Abstracts and Commentaries

Male Infertility

Investigations on semen analysis capabilities and quality control measures in laboratories with different management modes.

Molecular Remodeling of the Sperm Proteome Following Varicocele Sclero-Embolization: Implications for Semen Quality Improvement.

Improving sperm selection strategies for assisted reproduction through closing the knowledge gap in sperm maturation mechanics.

Peyronie's Disease

A novel autologous material for the surgical treatment of Peyronie's disease: the outer plate of the prepuce.

Erectile Dysfunction

Pre-Implementation Assessment of a Sexual Health eClinic in Canadian Oncology Care.

Association between preoperative serum testosterone levels and the risk of postoperative erectile function after nerve-sparing radical prostatectomy: a systematic review and meta-analysis.

Clinical value of spontaneous cavernous activity evaluation in identifying misdiagnosed corporal venous occlusive dysfunction in psychogenic erectile dysfunction.

Prevalence of mental health evaluation in erectile dysfunction clinical trials.

BPH - Benign Prostatic Enlargement

The Current State of Artificial Intelligence for Benign Prostatic Hyperplasia.

Health technology assessment (HTA) of prostatic urethral lift (PUL) for the treatment of benign prostatic hyperplasia (BPH) in the Italian context.

Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia.

Clinical efficacy and safety of transurethral prostate blue laser vaporization versus green laser vaporization in the treatment of benign prostatic hyperplasia with different prostate volumes: A retrospective comparative study.

Penile & Urethral Cancers

Diagnosis, Treatment and Survival From Penile Cancer: Real-World Data From the National Health Service England Between 2013 and 2020.

Excision of Penile Squamous Cell Carcinoma Is Associated With High Rates of Positive Surgical Margins.

Immune checkpoint inhibitor therapy for advanced HPV-related penile squamous cell carcinoma: a rare case report.

Lymphovascular Invasion Predicts Cancer-Specific Mortality in Penile Localized Squamous Cell Carcinoma - Beyond the Abstract

Testicular Cancer

Beyond germ cell tumors: focus on Leydig cell neoplasms from a single-center experience.

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours.

Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers.

Post-prostatectomy incontinence

Urologists Self-Report Rates of Post-Prostatectomy Incontinence (PPI) and Referral Patterns for Treatment.

Prostate Cancer

Clarity Successfully Completes $203 Million Institutional Placement

Co-PSMA Trial: Recruitment Successfully Completed

Real-World Experience of 18F-PSMA-1007 Positron Emission Tomography-Computed Tomography Scanning for Initial Staging of High-Risk Nonmetastatic Prostate Cancer: Scan Results and Treatment Decisions.

High-dose-rate (HDR) brachytherapy boost in combination with external beam radiotherapy for localized prostate cancer: An evidence-based consensus statement.

Survival benefit associated with first-line androgen receptor pathway inhibitors for de novo metastatic castration-sensitive prostate cancer.

Efficacy and safety of rechallenge therapy with [177Lu]Lu-PSMA in metastatic castration-resistant prostate cancer: a systematic review and meta-analysis.

A prospective, multi-centre trial of PSMA-PET compared to FDG-PET for staging of newly diagnosed high risk prostate cancer.

Oncological Outcomes After Robotic Salvage Radical Prostatectomy in Patients Primarily Treated With Focal Versus Radiation Therapy: A Junior ERUS/YAU Collaborative Study.

Clinical Outcomes of Patients With Metastatic Prostate Cancer With Microsatellite Instability Treated With Pembrolizumab.

Postdiagnosis physical activity is associated with improved survival in prostate cancer patients treated with surgery but not with radiation therapy.

Predicting side-specific extraprostatic extension in prostate cancer using an 18F-DCFPyL PSMA-PET/CT-based nomogram.

Transcutaneous perineal-ultrasound guided prostate biopsy in men with rectal amputation.

National Cancer System Characteristics and Global Pan-Cancer Outcomes

Metformin for Patients with Metastatic Prostate Cancer Starting Androgen Deprivation Therapy: A Randomised Phase 3 Trial of the STAMPEDE Platform Protocol - Beyond the Abstract

Factors Associated with Recovery of Urinary Continence: A Multicenter Comparison of Pelvic Fascia-sparing and Standard Robotic-assisted Radical Prostatectomy.

Self-reported quality of recovery after radical prostatectomy-a prospective cohort study.

Moving from a registry to a learning health system: A case study of a Dutch prostate cancer registry.

A pilot study evaluating the safety and efficacy of En-bloc holmium laser enucleation of the prostate in patients with a history of radiation therapy or high intensity focused ultrasound for management of organ confined prostate cancer with review of the

Predicting ADC map quality from T2-weighted MRI: A deep learning approach for early quality assessment to assist point-of-care.

VISION, TheraP, LuTectomy and beyond - is there a role for lutetium therapy in biochemical recurrence?

A population-based analyses of the evolving management of cN1M0 prostate cancer in the PSMA-PET era.

Irreversible Electroporation for Prostate Tissue Ablation in Patients with Intermediate-risk Prostate Cancer: Results from the PRESERVE Trial.

Novel Therapeutic Strategies for Metastatic Prostate Cancer Care.

Patient-reported Outcomes in KEYLYNK-010: Pembrolizumab Plus Olaparib Versus Abiraterone or Enzalutamide for Participants with Biomarker-unselected, Previously Treated Metastatic Castration-resistant Prostate Cancer.

Dose-response mapping of bladder and rectum in prostate cancer patients undergoing radiotherapy with and without baseline toxicity correction.

Safety and Efficacy of Tarlatamab in patients with Neuroendocrine Prostate Cancer: Results from the Phase 1b DeLLpro-300 Study.

Prognostic Impact of Lymph Node Yield in a Phase III Clinical Trial (NRG/RTOG 9601) of Prostate Cancer Patients Treated With Salvage Radiation Following Prostatectomy.

Deferral of systemic therapy in patients with oligorecurrent prostate cancer treated with metastasis-directed radiotherapy.

Prostate radiotherapy in patients with metastatic hormone-sensitive prostate cancer: A systematic review and meta-analysis of randomised controlled trials.

[177Lu] Lu-PSMA-617 treatment for metastatic castration-resistant prostate cancer (mCRPC) with cerebral and cerebellar metastases.

177Lu-PSMA-617 Consolidation Therapy after Docetaxel in Patients with Synchronous High-Volume Metastatic Hormone-Sensitive Prostate Cancer: A Randomized, Phase 2 Trial - Beyond the Abstract

Prostate-Specific Antigen Response as a Prognostic Factor for Overall Survival in Patients with Prostate Cancer Treated with Androgen Receptor Pathway Inhibitors - Beyond the Abstract

A Comparison of Surgical Outcomes Between Outpatient and Inpatient Robot-Assisted Radical Prostatectomy: A Systematic Review and Meta-Analysis - Beyond the Abstract

Eliciting the Impact of Metformin and Statins on Prostate Cancer Outcomes from a Real-life National Database Analysis - Beyond the Abstract

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