Uroalerts Men's Health Weekly

July 14, 2025

Videos

Peer-to-Peer Clinical Conversations

Urinary and Gut Microbiome Contribute to Androgen Production in Cancer Patients - Karen Sfanos & Jason Ridlon

Karen Sfanos

Andrea Miyahira interviews Karen Sfanos and Jason Ridlon about a Nature Microbiology paper on bacterial androgen production.

Androgen Receptor Inhibition and MHC Class 1 Expression in Prostate Cancer - Lisa Chesner

Lisa Chesner

Andrea Miyahira speaks with Lisa Chesner about the relationship between androgen receptor inhibition and MHC class I expression in prostate cancer.

Beyond the Abstracts

Minimal Approach to Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia: Is Less More? - Beyond the Abstract

Xipag® for LUTS Management in BPH Patients: Evaluating a Novel Nutraceutical Approach - Beyond the Abstract

Conference Coverage

ASCO GU 2025: Landscape of New Trials and Targets in Refractory Germ Cell Tumors

ASCO GU 2025: Primary Retroperitoneal Lymph Node Dissection in Stage II Seminoma: Management Strategies and Current Controversies

ASCO GU 2025: High-Dose Chemotherapy in Testicular Cancer: Current Evidence and Clinical Indications

SUO 2024: Top Papers in Testicular Cancer 2024

SUO 2024: Spotting Metastatic Masqueraders: How to Avoid Inappropriate Chemotherapy Administration for Testicular Cancer

Articles

Editor Selected Abstracts and Commentaries

Androgen Deficiency

A cross-sectional survey of experiences and outcomes of using testosterone replacement therapy in UK men.

Male Infertility

The Utility of Sperm DNA Fragmentation as a Diagnostic Tool for Male Infertility and Its Predictive Value for Assisted Reproductive Technology Outcomes.

Transcriptome sequencing reveals significant RNA variation in human sperm samples.

Comparing remote smartphone-based semen assessments with laboratory evaluations in men unselected for fertility concerns.

The effects of kidney transplantation on sex hormones, sperm parameters, and fertility rate in males: A systematic review.

Peyronie's Disease

Review of Current Non-Invasive Peyronie's Disease Management: A Changing Reality.

Prostatitis

Three-Glass Test to Culture Prostate Secretion and Semen of Chronic Prostatitis Patients.

Erectile Dysfunction

Low-intensity shockwave therapy for erectile dysfunction.

Efficacy of Chinese herbal medicine in the treatment of anxiety and depression in male sexual dysfunction: a systematic review and meta-analysis.

Surgeon-led vs. nurse-led postoperative follow-up after dilep: impact on erectile function recovery and patient-reported outcomes.

BPH - Benign Prostatic Enlargement

Efficacy of Holmium Laser Enucleation of the Prostate in Patients With Detrusor Underactivity or Acontractile Bladder.

Prostate artery embolization for benign prostatic hyperplasia: a retrospective single-center study of clinical outcome.

Bladder neck contracture post-treatment for benign prostatic hyperplasia: a systematic review and meta-analysis of randomized clinical studies.

Niche No More? Mapping US Trends and Regional Disparities in Holmium Laser Enucleation of the Prostate from 2018 to 2022.

Thulium fiber laser versus holmium MOSESTM laser enucleation of the prostate for the treatment of benign prostatic hyperplasia: a randomized prospective clinical study.

Penile & Urethral Cancers

Penile Cancer Profile in a Central European Context: Clinical Characteristics, Prognosis, and Outcomes-Insights from a Polish Tertiary Medical Center.

RNA-seq of penile squamous cell carcinoma shows ODC1 overexpression is associated with worse overall survival.

Testicular Cancer

A study of subjective memory impairment in long-term testicular cancer survivors.

Near-complete resolution of tumour thrombus in a patient with advanced non-seminomatous germ cell tumour: a multidisciplinary approach without surgical intervention.

Mapping regional disparities in testicular cancer mortality across Spain (2004-2023).

Usefulness of apparent diffusion coefficient values and magnetic resonance imaging histogram analysis for identifying histological types of preoperative testicular tumors.

Robotic Retroperitoneal Lymph-Node Dissection for Testicular Cancer: Initial Experience - Beyond the Abstract

Prostate Cancer

Is [177Lu]Lu-PSMA-617 Redefining Value in mCRPC Care? A Meta-Analysis of Clinical and Economic Endpoints.

Efficacy of Anti-PD-(L)1 Immunotherapy in Patients with DNA Mismatch Repair-deficient Metastatic Castration-resistant Prostate Cancer.

Clinical and Transcriptomic Characterization of Metastatic Hormone-Sensitive Prostate Cancer Patients with Low PTEN Expression.

Stereotactic Salvage Radiotherapy for Macroscopic Prostate Bed Recurrence After Prostatectomy: STARR (NCT05455736): An Early Analysis from the STARR Trial.

Randomized Phase 2 Trial of Presurgical Androgen Deprivation Therapy With or Without Axitinib in Prostate Cancer Presenting With Lymph Node Metastasis.

Treatment of biochemical recurrence after primary therapy with curative intent.

XTANDI® Plus Leuprolide Significantly Improves Survival Outcomes in Men with Non-Metastatic Hormone-Sensitive Prostate Cancer with High-Risk Biochemical Recurrence

Acute toxicity of SBRT in localized prostate cancer: A Spanish multicenter study.

Survival outcomes for men with metastatic castration-resistant prostate cancer (mCRPC) with and without homologous recombination deficiencies (HRD) treated with radium 223: Princess Margaret Cancer Centre (PMCC) experience.

Plasma epigenomic profiling reveals treatment-emergent squamous transformation in prostate cancer.

Evaluating PI-RADS lesions and clinically significant prostate cancer in Black and Asian men: a PREVENT randomized clinical trial secondary analysis.

U.S. FDA Grants Artera Breakthrough Device Designation for AI-Powered Software Transforming Prostate Cancer Care

Human kallikrein 2: A novel lineage-specific surface target in prostate cancer.

AI lesion tracking in PET/CT imaging: a proposal for a Siamese-based CNN pipeline applied to PSMA PET/CT scans.

What's in a name? Why differentiation between biochemical recurrence and metastatic prostate cancer matters.

Cell-free DNA whole-genomes reveal chromosomal rearrangements associated with heterogeneity and stem cell-like castration-resistant prostate cancer.

Polygenic Risk Scores for Prostate Cancer: Comparative Evaluations in UK and Australian Cohorts.

Usefulness of free PSA ratio to enhance detection of clinically significant prostate cancer in patients with PI-RADS

Guideline of guidelines: a critical appraisal of the evidence for PSA retesting intervals.

Utilization, Acute Complications, and Delays in Treatment Associated with Rectal Spacers for Prostate Cancer Radiotherapy.

Patient-Reported Quality of Life in PROFIT, a Phase 3 Randomized Clinical Trial Evaluating Moderately Hypofractionated Radiotherapy for Intermediate-risk Prostate Cancer - Beyond the Abstract

Rectal spacer use and bowel, urinary, and sexual dysfunction diagnosis and related procedures among men receiving prostate radiotherapy: US county-level analysis.

Development and retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies: study protocol.

Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer.

External Validation on a Japanese Cohort of a Computer-Aided Diagnosis System Aimed at Characterizing ISUP ≥ 2 Prostate Cancers at Multiparametric MRI.

Should we redefine the Phoenix criteria for biochemical recurrence after primary radiotherapy?

Biopsy-free radical prostatectomy: a narrative review considering rationale, limitations, and current data.

Immunotherapy in metastatic prostate cancer.

The Natural History of Confirmed Grade Group 1 Prostate Cancer Managed with Active Surveillance in the Modern Era.

Generative Artificial Intelligence in Prostate Cancer Imaging.

Optimizing Biopsy Decisions in PI-RADS 3 Lesions: Cross-Institutional Validation of a Local Clinical Risk Model - Beyond the Abstract

GLP-1 Agonist Use Among Men with Localized Prostate Cancer: A Narrative Review and Rationale for Prospective Clinical Trials - Beyond the Abstract

PSMA MRI Guided Prostate SABR ARGOS-CLIMBER Phase I/II Trial: A Primary Endpoint Analysis - Beyond the Abstract

Comparative Adverse Event Profiles of Triplet Therapy Versus Docetaxel-Based Therapy in Patients with Metastatic Prostate Cancer: A Multicenter Retrospective Study - Beyond the Abstract

Updated Prostate Cancer Risk Groups by Prostate-specific Membrane Antigen Positron Emission Tomography Prostate Cancer Molecular Imaging Standardized Evaluation (PPP2): Results from an International Multicentre Registry Study - Beyond the Abstract

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