Prostate Cancer Daily

January 27, 2026

Videos

Peer-to-Peer Clinical Conversations

AI Applications in Prostate Cancer Pathology and Prognostics - Tamara Lotan

Tamara Lotan

Tamara Lotan discusses artificial intelligence applications in prostate cancer pathology.

Targeting NSD2 to Reverse Treatment Resistance in Advanced Prostate Cancer - Jia Li

Jia Li

Zachary Klaassen is joined by Jia Li to discuss NSD2 targeting and lineage plasticity in advanced prostate cancer.

Beyond the Abstracts

First-Line [177Lu]Lu-PSMA-617 Therapy Without ADT, Chemotherapy, or Local Therapy for Metastatic Hormone-Sensitive Prostate Cancer - Beyond the Abstract

Using Patient-Reported Outcomes from the PROCLAIM Trial to Assess the Impact of Universal Germline Genetic Testing for Prostate Cancer Patients - Beyond the Abstract

Conference Coverage

SUO 2025: Stratifying Risk in Active Surveillance for Prostate Cancer Using Decipher Genomic Classifiers and Gleason Grade Group

SUO 2025: PSMAndARPI: Phase II Study of 177Lu-PSMA-617 Plus Androgen Receptor Pathway Inhibitor versus 177Lu-PSMA-617 as First-line Treatment of Prostate-specific Membrane Antigen-positive Progressive Metastatic Castration-resistant Prostate Cancer

SUO 2025: PROSTest, a Novel Blood-based mRNA Assay, Can Accurately Predict Outcomes to 177Lu-PSMA in Metastatic Castration Resistant Prostate Cancer

ESMO 2025: Retreatment with 177Lu-PSMA-617 in mCRPC Patients Treated Under the French Early Access Program

ESMO 2025: Discussant – Phase III Trial of [177Lu]Lu-PSMA-617 Combined with ADT + ARPI in Patients with PSMA-Positive Metastatic Hormone-Sensitive Prostate Cancer (PSMAddition)

Articles

Editor Selected Abstracts and Commentaries

Prostate Cancer

Prostate cancer cells converge to an inflammatory-like state upon metastatic dissemination.

The 'Comparison of diagnostic accuracy of Luminal Index and standard of care MRI for Accelerated deTEction of prostate cancer' (CLIMATE) trial protocol.

Risk of bone fractures in patients with prostate cancer treated with maximal androgen blockade therapy: a systematic literature review and meta-analysis.

Real-World Burden and Management of Late Genitourinary Toxicity After Prostate Radiotherapy: Insights from IRRADIaTE, the Italian Registry of Radiotherapy-Associated Disorders and Urological Treatment & Evaluation.

Triplet therapy versus androgen receptor pathway inhibitor-doublet therapy in metastatic castration-sensitive prostate cancer: a real-world multicenter retrospective comparison.

Lack of survival benefit of pelvic lymph node dissection for patients with radical prostatectomy and postprostatectomy radiotherapy.

Assessing the Detection Power of Genome-Wide Copy Number Variation Profiles in Prostate Cancer Using Simulated Shallow Whole-Genome Sequencing Data.

Comparison of Cancer Detection Between Transrectal and Transperineal Prostate Biopsy in an Active Surveillance Cohort.

Local prostate cancer recurrence after radiotherapy or brachytherapy. What now? Retrospective analysis of salvage prostatectomy and salvage cryoablation.

Radical prostatectomy without prior biopsy in patients with positive PSMA PET and/or mpMRI: A practiced but poorly documented approach. Retrospective multicenter cohort study.

Optimizing management of metastatic castration-sensitive prostate cancer: From therapeutic advances to personalized care.

Diagnostic accuracy and outcomes of lymph node staging in intermediate-risk prostate cancer.

Are Urologists and/or Radiation Oncologists Biased when Reporting of Advantages and Disadvantages of Surgery versus Radiation in Consultations for Early-Stage Prostate Cancer?

Association Between the PRIMARY Score at Staging Prostate-specific Membrane Antigen Positron Emission Tomography and Overall Survival Among Patients with Newly Diagnosed Prostate Cancer - Beyond the Abstract

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