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PEER-TO-PEER CLINICAL CONVERSATIONS |
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A Novel Sublingual Vaccine for Prevention of Recurrent Urinary Tract Infections in Women
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J. Curtis Nickel, MD, FRCSC
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| Diane Newman is joined by J. Curtis Nickel as he highlights his 2021 American Urological Association (AUA) presentation of a novel sublingual vaccine for the prevention of urinary tract infections in women.
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| The OAB Clinical Care Pathway Mobile APP |
| Stephen R. Kraus, MD, MBA, FACS |
| In this informational video presentation, Stephen Kraus provides an update on the SUFU overactive bladder (OAB) Clinical Care Pathway as a dissemination effort to broadcast the advantages of the pathway for both physicians and patients. |
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| The Prevalence of Antimicrobial Resistant Pathogens Causing Recurrent Urinary Tract Infections Amongst Female Patients in an Outpatient Female Pelvic Medicine Practice in the NY/NJ Metropolitan Area |
| Marcus Cunningham, Barry N. Kreiswirth, Claudia Manca, Barun Mathema, Jared Benjamin |
| This was a retrospective cross-sectional study to examine the clinical and microbiological properties of all women with culture-confirmed singular or sporadic urinary tract infections (sUTI) compared to those with recurrent UTIs (rUTI) in an outpatient female urology practice. |
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| Social Media Analytics of Overactive Bladder Posts: What do Patients Know and Want to Know? - Beyond the Abstract |
| Gabriela Gonzalez, MD, MPH and Jennifer T. Anger, MD, MPH |
| To date, research has focused less on prevention of lower urinary tract symptoms (LUTS) and more on identifying causes and phenotypes of LUTS. The impact of behavioral, psychological, and socioeconomic contributors to LUTS is understudied. To identify strategies for promoting bladder health and reducing LUTS in women, the National Institute of Diabetes and Digestive and Kidney Diseases supported the development of the Prevention of Lower Urinary Tract Symptoms (PLUS) Consortium. |
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| Outcomes of a Single Trigone-Only vs. 20 Trigone-Sparing Injections of OnabotulinumtoxinA for Refractory Overactive Bladder (OAB) - Beyond the Abstract
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| Eboo Versi, MD, Ph.D.
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| To compare the safety and durability of a single intravesical trigonal-only versus 20 trigone-sparing injections of OnabotulinumtoxinA (BTA) for refractory OAB, a chart review of all idiopathic OAB patients treated with BTA from January 2016 to December 2018 was performed. Outcomes measures included: inter-injection interval, post-void residual (PVR), urinary tract infections (UTI), urinary retention requiring catheterization, and procedure time (min). Statistical analyses were performed using independent sample t-tests.
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| The Urinary Microbiome Impacts Urologic Disease |
| J. Curtis Nickel, MD, FRCSC |
| J. Curtis Nickel discusses the impact of the urinary microbiome on urologic disease. Dr. Nickel notes that the traditional dogma is that the urinary tract is normally sterile, a belief that has persisted until the last decade. Interestingly, when the Human Microbiome Project was undertaken (2007-2016), the urinary tract was not included. Dr. Nickel notes that since then, increased utilization of next-generation sequencing has improved and changed our understanding of microbes. |
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| Trends In Diagnostic Workup and Surgical Management For Recurrent Urinary Tract Infections
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| Victoria Edmonds, BS
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| There is variability in the evaluation, treatment, and referral patterns for recurrent urinary tract infections (rUTI). This group sought to analyze patterns in the workup and surgical management of rUTI at their institution. Data collected included demographics, provider specialty, and workup, including the performance of genitourinary exam, urodynamic evaluation, cystoscopy, and imaging and if the patient underwent a surgical procedure and type.
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| Toileting Behaviors in Adult Women with Recurrent Urinary Tract Infections in a Large Cross-Sectional Survey Study
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| Elisabeth Sebesta, MD, Elizabeth Rourke, MD, Casey Kowalik, MD, Melissa Kaufman, MD, Roger Dmochowski, MD, W. Stuart Reynolds MD
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| The aim of this secondary analysis was to assess whether women with recurrent urinary tract infections (rUTIs) report more unhealthy bladder and bowel habits. The sample was 6,074 non-institutionalized, adult U.S. women recruited through online ResearchMatch. Women completed validated questionnaires assessing demographic and clinical history, toileting behaviors (TB-WEB), urinary symptoms (ICIQ-FLUTS), and bowel habits (ICIQ-BS). Subjects were excluded if they were pregnant, used a urinary catheter, or had a history of cystectomy, neurogenic bladder, or neurological disorder.
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