WCE 2019: Does Previous History with Urosepsis Predict the Likelihood of Urosepsis Post-Ureteroscopy

Abu Dhabi, United Arab Emirates (UroToday.com) Currently, there is a scarcity of information that can be used to predict the likelihood of recurrent urosepsis for patients who have recently undergone ureteroscopy for initial urosepsis in addition to having obstructing calculi. It is even difficult to predict the recurrence of urosepsis in these patients even if they were found to have a positive urine culture postoperatively and were treated successfully with antibiotics prior to ureteroscopy.  For Dr. Omar Ramadan and his team, this was an issue worth investigating. In his study, he aimed to predict the likelihood of a cohort of his patients developing urosepsis following definitive ureteroscopy.

For his patient cohort, he recruited patients who fit the following inclusion criteria: (1) patients who had a previous history of urosepsis due to obstructing stones, (2) patients with documented positive urine cultures and (3) patients who had been treated successfully with antibiotics before electing to undergo ureteroscopy. He found that out of his 100-patient cohort, patients with a previous history of urosepsis had similar patient characteristics and stone-free rates compared to patients without a previous history of sepsis. These patients who previously had urosepsis also were found to have higher rates of post-URS urosepsis compared to those did not.

Dr. Ramadan concluded his presentation by explaining that a previous history of urosepsis can often predict the likelihood of further urosepsis for patients who elect to undergo ureteroscopy. Patients who initially presented with urosepsis were found to be at a higher risk of contracting further episodes of urosepsis as a result of definitive ureteroscopy. He recommended that these patients should be closely managed by a primary care provider or urologist following ureteroscopy for the treatment of urosepsis.

Presented by: Omar Ramadan, MBChB, MSc. Urol, MRCS- Eng, Stone Fellow & Urology Registrar/Resident, Department of Urology, Kent & Canterbury Hospital, East Kent Hospitals NHS Foundation Trust., Canterbury, United Kingdom

Written by: Andrew Shea Afyouni, BS, Junior Research Specialist and Medical Student, University of California, Irvine Department of Urology at the 37th World Congress of Endourology (WCE) – October 29th-November 2nd, Abu Dhabi, United Arab Emirates