SUFU 2019: Can We Avoid Time-Consuming Frequency-Volume Chart to Diagnose Underlying Pathophysiological Mechanisms of Nocturia in Some Patient Populations?

Miami, FL ( The primary purpose of this study was to assess possible causes and the overall prevalence of three primary categories of nocturia: nocturnal polyuria (NP), reduced bladder capacity, and global polyuria. Researchers state that current prevalence data is underestimated. They hypothesized that frequency volume chart (FVC) can be a potential tool to differentiate pathophysiological mechanisms behind nocturia for the tailored therapy algorithm.

A retrospective data abstraction was conducted for the new patients who encountered a provider between May 2010 and September 2016 and received a diagnosis of nocturia. Former diagnosis of genitourinary malignancy, primary OAB complaints, recurrent urinary tract infections, and incomplete FVC were the exclusion criteria. One hundred and nineteen charts were considered eligible for analysis.

The study showed that nocturnal polyuria was the most common categories with a prevalence of 79.9%. Reduced bladder capacity defined as a maximum voided volume of <250 ml, was identified in 40.1% of patients. Global polyuria was diagnosed in 3.3% of individuals and 35.3% were mixed (2 or more mechanisms) (Figure 1).

Figure 1
UroToday SUFU2019 Frequency Volume Chart

According to the univariate data analysis, age of 85 years and older and 4 or more nocturic episodes per night were linked to the risk behind nocturnal polyuria. However, when adjusted for age ≥ 85, subject’s BMI and gender, only high number of nocturia episodes (4 or more) was associated with NP (OR=6.6; p=0.001).

Presented by: Benoit Peyronnet, MD, University of Rennes, France

Written by: Hanna Stambakio, BS, Clinical Research Coordinator, Division of Urology, University of Pennsylvania, Twitter: @AStambakio at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Winter Meeting, SUFU 2019, February 26 - March 2, 2019, Miami, Florida