SUFU 2020: Which Urodynamic Parameters can Predict Outcomes of Intravesical Injections of Onabotulinum Toxin A for Overactive Bladder

Scottsdale, Arizona ( This team asks the question of whether pre procedure urodynamics can predict the outcome of patients undergoing Onabotulinum toxin A injection for refractory overactive bladder. A retrospective review was performed on 418 patients with a mean age of 61. 126 were men. The time period was between 2006-2018. Outcomes were measured using a 5 question PGII. 74% of the patients had urodynamics available for review, 214 women and 95 men. 69% of these cases had idiopathic detrusor activity (IDO).


They were able to correlate successful treatment outcomes with women who were diagnosed with IDO vs men and women without IDO. The only urodynamic parameter that influenced a successful outcome was in women with increased duration of detrusor contractions.

Presented by: Mehwash Nadeem, Clinical fellow in Female, Functional, Restorative Urology and Neuro-Urology, University College London Hospitals NHS Foundation Trust
Co-Authors: Kristina Aleksejeva, Gemma Scrimgeour, Richard Axell, Habiba Yasmin, Daniyal Motan, Stephen Unterberg, Mahreen Pakzad, Rizwan Hamid, Jeremy Ockrim, Tamsin Greenwell
FFR Urology, University College London Hospital

Written by: Lira Chowdhury, DO, Urology Specialist, Urology Partners of North Texas, PLLC, Fort Worth, Texas at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Winter Meeting, SUFU 2020, February 25 - February 29, 2020, Scottsdale, Arizona