This group from Iran provide their small single-institution experience with repeat TURBT. They examined 107 patients with either T1 or any high-grade urothelial carcinoma on TURBT – there is no comment on whether this was retrospective/prospective, initial diagnosis, etc. Repeat TURBT was completed within 6 weeks.
They identified upstaging – not defined in the abstract – in 11 patients (10.3%) and residual tumor of the same grade/stage in 18 patients (16.8%). Tumor size, multifocality, and presence of muscle at resection were all associated with upstaging/upgrading – however, they don’t document whether the were associated with more or less upstaging/upgrading.
Among 48 patients with single, small (<3 cm) tumors who underwent adequate resection initially (muscle in specimen), neither upstaging or upgrading was noted. They suggest that this subset, there may be a role to avoid repeat TURBT.
However, this single institution small series makes it quite difficult to make any significant conclusions. There are trials that approaching this question prospectively.
Presented by: Mohsen Ayati
Written by: Thenappan Chandrasekar, MD, Clinical Fellow, University of Toronto, twitter: @tchandra_uromd, at the 37th Congress of Société Internationale d’Urologie - October 19-22, 2017- Lisbon, Portugal