Dr. Ahmadi et al. investigated BLC in detecting invasive tumors, defined as ≥pT1 lesions, in a prospective, multi-institutional database. In their series of 47 patients, 11% of all invasive lesions were white light (-) and blue light (+). Notably, in 82% of patients who underwent radical cystectomy, the high-risk features on trans urethral resection of bladder tumor (TURBT) leading to definitive surgical management were found only on BLC. These investigators provide a rationale for use of BLC to increase the detection of high-risk lesions along the spectrum of NMIBC and muscle-invasive bladder cancer (MIBC).

Presented by: Hamed Ahmadi, MD, SUO Fellow at the University of Southern California, Los Angeles, California, USA