AUA 2019: Treatment Related Outcomes for Patients with Atypical Peyronie’s Disease

Chicago, IL (UroToday.com) Dr. El-Khatib wanted to follow and track the outcomes of patients presenting with atypical Peyronie’s Disease (PD). He outlines atypical PD as patients presenting with indentation, multiplanar curvature, ventral curvature, and an hourglass deformity.

Of the patients that were considered in the stable phase of PD, 42 patients presented with atypical PD. These 42 patients were then divided into the 4 different categories: 32 with indentation, 14 with multiplanar curvature, 10 with ventral curvature, and 10 with an hourglass deformity; patients were counted multiple times if they fell into more than one category. Of the 42 patients, only 31 pursued treatment with XIAFLEX® being the most popular treatment of choice.

Dr. El-Khatib continued by outlining the treatment options presented to the patients: XIAFLEX®, PEG, Plication, and IPP. All of these treatments were successful except for 1 penile fracture that required surgical repair. For both indentation and hourglass deformities, patients preferred to be treated with XIAFLEX®.

In this cohort of patients, Dr. El-Khatib emphasizes the fact that atypical patients with PD, make up the majority of patients (56.8%) and the results of this study had outcomes similar to the IMPRESS trials, which looked at typical PD patients.


Presented by: Farouk M. El-Khatib, MD, University of California-Irvine

Co-authored by: Linda M. Huynh, Mohomad M. Osman, Maxwell Towe, Faysal A. Yafi, University of California-Irvine

Written by: Joshua Tran, Department of Urology, University of California-Irvine at the American Urological Association's 2019 Annual Meeting (AUA 2019), May 3 – 6, 2019 in Chicago, Illinois

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