ASCO GU 2017: Can focal therapy impact perioperative, oncological, and functional outcomes in men who underwent focal therapy salvage robotic-assisted radical prostatectomy? A retrospective matched-pair comparative study. - Poster Session Highlights
Orlando, Florida USA (UroToday.com) This multinational study sought to identify the differences in outcomes subsequent to salvage robotic assisted radical prostatectomy (RARP) vs. RARP in treatment naïve patients. Of 2775 undergoing RARP, 25 were performed in the salvage setting after failed focal therapy. In a 1:2 matched analysis, rates of continence at 1 and 2 years postoperatively were not significantly different. However, potency rates were found to be lower in the salvage RARP patients.
Expectedly, salvage RARP was associated with higher biochemical recurrence, with hazard ratio of 14.65 (0.022). It is unclear to what extent androgen deprivation therapy was used in either group and whether this influenced the results.