UroAlert - GU Oncology Daily

June 18, 2026

Videos

Peer-to-Peer Clinical Conversations

Interim Phase 2 LEGEND Trial Results for Detalimogene in BCG-Unresponsive NMIBC - Ashish Kamat

Ashish M. Kamat

Ashish Kamat presents interim phase 2 LEGEND trial results for detalimogene voraplasmid, a non-viral plasmid gene therapy delivering IL-12 and RIG-I genes intravesically in BCG-unresponsive non-muscle invasive bladder cancer.

Safety and Dosing of Lutetium-PSMA in the Pre-Chemotherapy PSMAfore Trial - Oliver Sartor

Oliver Sartor

Zachary Klaassen speaks with Oliver Sartor about safety and dosing in the PSMAfore trial examining lutetium PSMA-617 in metastatic castration-resistant prostate cancer.

Beyond the Abstracts

CT-Based Renal Artery Caliber Change as a Potential Imaging Marker of Treatment Response in Renal Cell Carcinoma; an Exploratory Imaging Study - Beyond the Abstract

Digital PCR-Based Uromonitor for Molecular Detection of Bladder Cancer: A Multicenter Validation Study Comparing Quantitative PCR and Urine Cytology - Beyond the Abstract

Conference Coverage

ASCO 2026: TROPION-Urothelial03: A Phase 2/3 Study of Datopotamab Deruxtecan + Platinum Based Chemotherapy versus Gemcitabine + Platinum Based Chemotherapy

ASCO 2026: Avelumab + Sacituzumab Govitecan versus Avelumab Monotherapy as First Line Maintenance Treatment for Advanced Urothelial Carcinoma: Updated Subgroup Analyses of JAVELIN Bladder Medley Based on Metastatic Sites

ASCO 2026: ctDNA Analysis in Participants with RCC Treated with Adjuvant Pembrolizumab in the KEYNOTE-564 Trial

AUA 2026: Cohesion-Interfacial Enhanced Adhesive Hydrogel Patch for Hemostasis and Tissue Injury Repair After Partial Nephrectomy

AUA 2026: Detection of Bladder Cancer in Patients with Microscopic Hematuria using Oncuria-Detect, Interim Analysis of an International Prospective Study

Articles

Editor Selected Abstracts and Commentaries

Bladder Cancer

Surrogacy of Intermediate Clinical Endpoints for Overall Survival in Patients With Localized Muscle-Invasive Bladder Cancer.

Analysis of real-world re-induction outcomes with nadofaragene firadenovec in patients with Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer.

Targeting HER2 in Urothelial Carcinoma: Why Histologic Subtypes and Divergent Histologies Matter - Beyond the Abstract

Penile & Urethral Cancers

Immunohistochemistry for p16 and p53 Provides Substantial Agreement With Molecular Tests in Penile Cancer.

Renal Cancer

Assessment of Multiple Prognostic Scores in Patients With Metastatic Renal Cell Carcinoma Receiving First-Line, Immune-Based Combinations.

A preoperative Artificial Intelligence model to estimate cancer-specific mortality in nonmetastatic kidney cancer patients.

Outcomes of Immune-Checkpoint Inhibitor Rechallenge in Metastatic Clear-Cell Renal Cell Carcinoma: Results from a Global Real-World Evidence Study - Beyond the Abstract

Prostate Cancer

Single-port robotic radical prostatectomy: early results from a UK centre.

Integrative Oncology for Prostate Cancer: A Narrative Review.

3D Genome Architecture and Epigenetic Regulation of Lineage Identity in Advanced Prostate Cancer.

Targeted Prostate Health Checks for prostate cancer in men at high risk: a feasibility pilot in primary and secondary care in North East London.

Concomitant MRI-detected and MRI-undetected Prostate Cancer with Implications for Biopsy Strategies and Focal Therapy Planning: An Analysis of the PROMIS and PICTURE Trials.

New Swedish Biopsy Needle Receives FDA Approval – Secures SEK 17 Million in Capital

Testicular Cancer

Hyperaccuracy Three-Dimensional Model and Augmented Reality/Mixed Reality for Robot-Assisted Retroperitoneal Lymph Node Dissection in Testicular Cancer.

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