UroAlert - GU Oncology Daily

July 20, 2026

Videos

Peer-to-Peer Clinical Conversations

ENLIGHTED Trial Update with VTP for Low-Grade Upper Tract Urothelial Cancer - Vitaly Margulis

Vitaly Margulis

Vitaly Margulis presents updated ENLIGHTED trial data, covering padeliporfin vascular-targeted photodynamic therapy for low-grade upper tract urothelial carcinoma.

Radiopharmaceuticals in Prostate Cancer Part 3A: Patient Selection and Treatment Sequencing - Tanya Dorff, Neal Shore & Dustin Boothe

Tanya Dorff

Tanya Dorff, Neal Shore, and Dustin Boothe discuss patient selection and treatment sequencing for lutetium-177 PSMA across the pre- and post-chemotherapy mCRPC settings.

Beyond the Abstracts

Avelumab First-Line Maintenance for Advanced Urothelial Carcinoma: Long-Term Outcomes from the JAVELIN Bladder 100 Trial in Patients with High Body Mass Index or Diabetes Mellitus - Beyond the Abstract

Pathologic Complete Response after Enfortumab Vedotin Plus Pembrolizumab in Node-positive Upper Tract Urothelial Carcinoma - Beyond the Abstract

Conference Coverage

ASCO 2026: TROPION-Urothelial03: A Phase 2/3 Study of Datopotamab Deruxtecan + Platinum Based Chemotherapy versus Gemcitabine + Platinum Based Chemotherapy

ASCO 2026: AI-Augmented Analysis of Quantitative ctDNA Burden and Longitudinal Kinetics to Identify Prognostic Risk Stratification in Metastatic Clear Cell RCC

ASCO 2026: Magnitude and Timing of Clinical Benefit Associated with Pathological Complete Response in Perioperative MIBC: A Reconstructed IPD Analysis of NIAGARA Trial

AUA 2026: Final Results of a Phase II Trial of BCG And Intravesical Gemcitabine for Patients With BCG-Exposed High-Grade Non-Muscle Invasive Bladder Cancer

AUA 2026: AMPLIFY: A Phase 3 Study of 64Cu-SAR-bisPSMA Positron Emission Tomography in Participants with Biochemical Recurrence of Prostate Cancer

Articles

Editor Selected Abstracts and Commentaries

Bladder Cancer

A ferroptosis-suppressive state drives resistance to bladder-preserving chemoradiotherapy in muscle-invasive bladder cancer.

Comprehensive clinical and genomic analysis of early onset cancer of the bladder and upper urinary tract.

Long-Term Outcomes of Neoadjuvant Chemotherapy (NAC) Prior to Bladder-Sparing Trimodality Therapy (TMT) for Patients With Muscle-Invasive Bladder Cancer (MIBC).

Pathological Assessment of Morcellated Tissue after ERBT: Insights from a Two-Round Delphi Survey - Beyond the Abstract

Renal Cancer

Fumarate hydratase-deficient renal cell carcinoma - results of the exploratory analysis in the SUNNIFORECAST trial comparing Ipilimumab plus Nivolumab vs standard of care as first line treatment.

Neoadjuvant therapies for clear cell renal cell carcinoma: review of current evidence and future applications.

Prostate Cancer

Prognostic Significance of the Modified Glasgow Prognostic Score and Systemic Immune-Inflammation Index in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Cabazitaxel.

Lutetium-177-PSMA radioligand therapy in metastatic hormone-sensitive prostate cancer: A systematic review of efficacy, safety, and combination strategies.

Long-term oncologic outcomes of patients with grade group 1 prostate cancer and pT3a disease on final pathology.

PI-RADS-stratified MRI-based PSA Density for Predicting Adverse Pathology after Robotic-assisted Laparoscopic Radical Prostatectomy.

Emerging antibody-drug conjugates in metastatic castration-resistant prostate cancer.

The Evolving PI-RADS Paradigm - Beyond the Abstract

The Predictive Role of [177Lu]Lu-PSMA-617 SPECT/CT Semiquantitative Parameters from the 1st RLT Cycle in Advanced mCRPC: A Preliminary Bicentric Lesion-Based Analysis - Beyond the Abstract

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