Uroalerts Men's Health Weekly

July 14, 2026

Videos

Peer-to-Peer Clinical Conversations

PTEN Loss and the Future of Precision Treatment in mHSPC - Karim Fizazi & Noel Clarke

Karim Fizazi

Karim Fizazi and Noel Clarke discuss CAPItello-281 results with Neeraj Agrawal.

Bladder-Centric Focus in BPH: Early Triage and a Five-Stage Model - Wayne Kuang

Wayne Kuang discusses his ManVsProstate initiative with Alan Wein, emphasizing bladder health preservation in BPH.

Beyond the Abstracts

Low GATA3 Predicts Worse Survival in Penile Cancer - Beyond the Abstract

New Insights into Nectin-4 Expression in Testicular Choriocarcinoma and Its Potential Treatment with Enfortumab Vedotin: Analysis of a Multi-Institutional Series and Association with Clinical-Pathological Features - Beyond the Abstract

Articles

Editor Selected Abstracts and Commentaries

Male Infertility

Embryonic mosaicism in severe male factor infertility is unrelated to sperm retrieval technique.

Alterations in the protein lactylation landscape of sperm from patients with varicocele-associated asthenozoospermia.

Occupational Heat Exposure and Fertility Stress as Independent Factors of Low Semen Quality: A Multidimensional Analysis.

Erectile Dysfunction

Short-term safety and preliminary patient-reported outcomes of bipolar radiofrequency therapy for mild-to-moderate erectile dysfunction: a prospective single-arm pilot study.

The association between obstructive sleep apnoea and erectile dysfunction: a systematic review and meta-analysis.

Quantifying the risk of sexual dysfunction in men treated with pelvic radiation therapy for locally advanced rectal cancer.

BPH - Benign Prostatic Enlargement

Frailty burden and symptomatic BPH/LUTS in aging men: evidence from two nationally representative population-based studies.

High-frequency irreversible electroporation versus transurethral resection of the prostate for benign prostatic hyperplasia (GIANT): a single-centre, randomised, double-blind, phase 3, non-inferiority trial.

Real-World Long-Term Outcomes of Rezūm Therapy for Large-Volume Benign Prostatic Hyperplasia: A Multicenter Cohort Study.

Comparative performance of mFI-5 and mFI-11 thresholds in predicting outcomes after holmium laser enucleation of the prostate.

Immune dysregulation in the prostates of C57BL/6Aire-/- mice mirrors that seen in human benign prostatic hyperplasia.

Prostate morcellation devices: a systematic review and meta-analysis of clinical outcomes and efficiency.

Aquablation for LUTS due to BPH in men with localized prostate cancer.

Penile & Urethral Cancers

Unmet needs in penile cancer: Review and perspectives from the Global Society of Rare Genitourinary Tumors.

Prognostic Role of PD-L1 in Penile Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.

Testicular Cancer

Prognostic Reclassification and Survival Outcomes in Intermediate-Risk and Poor-Risk Nonseminomatous Germ Cell Tumors: Single-Institution Experience From Western India.

A novel classification of testicular sex cord-stromal tumours from the Testicular Sex Cord-Stromal Tumour (TESST) group: a collaboration of the Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP).

Testis-sparing surgery for small testicular masses: Functional and oncological outcomes.

Presentation, Management, and Outcomes of Testicular Germ Cell Tumors by Age - Beyond the Abstract

Post-prostatectomy incontinence

Pre- and postoperative membranous urethral length on multiparametric magnetic resonance imaging predict stage-specific 0-pad continence recovery after robot-assisted radical prostatectomy.

Prostate Cancer

Autophagy Stress Responses in Localized Prostate Cancer: A Flux-Aware Framework for Disease-Relevant Interpretation.

Magnetic Resonance Imaging as a Predictor of Early Discontinuation of Active Surveillance in Patients with Prostate Cancer.

Physical Activity During Radiotherapy in Prostate Cancer: Feasibility, Outcomes, and Clinical Integration.

Targeted proteomics for the detection of androgen receptor variants in preclinical models of castration-resistant prostate cancer.

Sex hormone balance and PSA-derived biomarkers in cancer-free African migrant men in Italy: Implications for prostate cancer early detection.

Radioligand therapy in combination with CAR T cells overcomes the heterogeneous immunosuppressive prostate tumor microenvironment.

The performance of prostate-specific antigen density in long-term prostate cancer-mortality risk prediction.

Impact of number of bone metastases on cancer control outcomes in mHSPC, independent of the axial-skeleton CHAARTED definition.

Dosimetric analysis of post-radiotherapy sexual dysfunction in patients receiving definitive stereotactic body radiotherapy (SBRT) for prostate cancer: a secondary analysis of MIRAGE.

68Ga-PSMA PET/CT in biochemically recurrent prostate cancer: association with genomic data.

Novel Risk Scoring System for Patients with Metastatic Castration Resistant Prostate Cancer Treated with Lutetium-177-PSMA-617.

No racial disparities in prostate cancer-specific mortality after biochemical recurrence following radical prostatectomy or radiation therapy.

Real-world clinical outcomes, genetic testing patterns, and treatment patterns of patients with metastatic castration-resistant prostate cancer treated with olaparib monotherapy in the United States.

Outcomes of Neoadjuvant Radiotherapy Followed by Robotic Radical Prostatectomy in High-Risk Locally Advanced Prostate Cancer: A Prospective Pilot Study.

Enzalutamide in biochemically recurrent prostate cancer: clinical implications from EMBARK for real-world practice.

ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy.

Diabetes Is an Independent Risk Factor for Radiation-Induced Hematuria After Robotic Stereotactic Body Radiotherapy for Prostate Cancer.

Effectiveness of Enhanced Recovery After Surgery Protocols for Robot Assisted Radical Prostatectomy Radical Prostatectomy: A Systematic Review and Meta-Analysis.

Same-day Hyaluronic Acid rectal spacer for TRUS-guided HDR Prostate Brachytherapy: Feasibility and dosimetric outcomes.

Intrafraction Motion Mitigation by Rectal Spacers in Prostate SBRT: Balloon, Hydrogel, and No-Spacer Comparison - Beyond the Abstract

Blue Earth Therapeutics Announces First Participant Dosed in Phase 1 Clinical Trial Investigating Actinium (²²⁵Ac) rhPSMA-10.1 Injection in Metastatic Castration-Resistant Prostate Cancer

Impact of prostate mpMRI quality on diagnostic accuracy in prostate cancer: a prospective study.

Clinical and racial predictors of adverse pathology at radical prostatectomy: implications for undertreatment among patients receiving radiation and hormonal therapy.

Telehealth Utilization for Prostate Cancer Management in the Veteran Affairs Healthcare System: A Study from 2016 to 2023.

A ligandable PNT domain establishes ERG as a directly targetable oncogenic driver in prostate cancer.

CorePlus Integrates AI-Powered Prostate Cancer Risk Stratification Tool into its Digital Pathology Diagnostic Pathway — a First in Puerto Rico

Newly diagnosed high-risk localized prostate cancer after multiple [177Lu]Lu-PSMA radioligand therapy in the context of metastatic parotid carcinoma: a case report.

Germline CDK12 variants in aggressive prostate cancer.

Overall Survival with [177Lu]Lu-PSMA-617 Versus [177Lu]Lu-PSMA I&T: A Propensity Score-Matched Real-World Analysis.

Toward a Biopsy-Free Diagnosis of Prostate Cancer: Potential of Combined 18F-Flotufolastat PSMA PET and mpMRI.

Comparison of DeepSeek-V3.2 and ChatGPT-5.2 in the outpatient diagnosis and treatment of prostate cancer: a multicenter evaluation of application value and multilingual adaptability.

Screening for prognostic indicators in patients with metastatic castration-resistant prostate cancer after androgen receptor signaling inhibitor treatment for metastatic castration-sensitive prostate cancer.

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