UroAlert - GU Oncology Daily

June 26, 2026

Videos

Peer-to-Peer Clinical Conversations

Composite B Cell and CD8 T Cell Signature Combined with ctDNA in Adjuvant Bladder Cancer Immunotherapy - Burles Johnson & Roy Elias

Burles Johnson and Roy Elias discuss a composite B cell/CD8 T cell biomarker analysis, examining whether the B8T gene signature improves prognostic and predictive value beyond ctDNA status in post-cystectomy high-risk urothelial carcinoma from IMvigor010.

Real-World Trends in ADT Intensification for mHSPC from the Swedish Prostate Cancer Register - Paolo Zaurito

Paolo Zaurito

Paolo Zaurito presents nationwide Swedish registry data covering treatment trends in approximately 9,000 metastatic hormone-sensitive prostate cancer patients from 2016 to 2024.

Beyond the Abstracts

Targeting HER2 in Urothelial Carcinoma: Why Histologic Subtypes and Divergent Histologies Matter - Beyond the Abstract

Agreement of Axial T2-MRI Versus Contrast-Enhanced CT for Solid Renal Mass Active Surveillance - Beyond the Abstract

Conference Coverage

ASCO 2026: Phase II Study of Frontline Gemcitabine, 5-Flurouracil/leucovorin, and Cisplatin in Advanced Urachal and Non-Urachal Urinary Tract Adenocarcinoma

ASCO 2026: Subgroup Analyses by Disease Volume and De Novo/recurrent mHSPC in the PSMAddition Study of [177Lu]Lu-PSMA-617

ASCO 2026: Feasibility and Safety Results from RAD-IO: A Multi-Stage Trial of Durvalumab with Chemoradiotherapy with 5-FU and Mitomycin C in Pts with MIBC

AUA 2026: Patient Preferences, Treatment Received, and Quality of Life in the CISTO Study Comparing Radical Cystectomy or Bladder Sparing Therapy for Recurrent High-Grade NMIBC

AUA 2026: Detection of Bladder Cancer in Patients with Microscopic Hematuria using Oncuria-Detect, Interim Analysis of an International Prospective Study

Articles

Editor Selected Abstracts and Commentaries

Bladder Cancer

Evaluating the Surrogacy of Pathological Complete Response at Radical Cystectomy in Neoadjuvant-based Muscle-invasive Bladder Cancer Trials.

Predicting the Development of BCG-unresponsive Disease Among Patients with High-grade Non-muscle-invasive Bladder Cancer: An International Multicenter Analysis.

Oncological Outcomes of Non-Muscle Invasive Bladder Cancer in Patients Aged ≤45: A Retrospective Matched Cohort Study.

Penile & Urethral Cancers

Penile squamous cell carcinomas with the usual-type morphology can be HPV-associated - Routine p16/HPV testing should be performed in all penile squamous cell carcinomas regardless of morphology.

Renal Cancer

Impact of Elevated C-Reactive Protein on Survival Outcomes of Patients with Small Renal Masses: A Retrospective Multicenter Analysis.

Real-World Analysis of Metastatic Renal Cell Carcinoma Patients Treated with Pembrolizumab Plus Axitinib: Evidence from the Campania Oncology Network.

Metastatic Tumour Burden as Prognostic Factor in Nivolumab-Treated Metastatic Renal Cell Carcinoma: An Exploratory Study.

Prostate Cancer

Post-diagnosis physical activity in relation to mortality among prostate cancer survivors: a systematic review and meta-analysis.

Incidence and Short- to Intermediate-Term Oncological Outcomes of Pathological T0 Prostate Cancer After Robot-Assisted Radical Prostatectomy: A Multicenter, Retrospective Cohort Study in Japan (MSUG94 Group).

Development and validation of a multimodal artificial intelligence-based model for predicting post-prostatectomy treatment outcomes from baseline biparametric prostate magnetic resonance imaging.

Integrative genomic profiling of newly diagnosed prostate cancers progressing on surveillance.

The Effect of Prostate Volume and 5-Alpha Reductase Inhibitor Use on Grade Progression and Treatment Decisions in Patients with Prostate Cancer on Active Surveillance.

Optimal MRI sequence for predicting extraprostatic extension in prostate cancer: comparison of LCC and MaxRADD measurements.

PANDA-PLUS: Improved Dataset of Prostate Whole Slide Images from PANDA Challenge with Pixel-Level Expert Annotations - Beyond the Abstract

Quantifying the Renal Impact of [177Lu]Lu-PSMA-617: A Longitudinal Analysis of Real-World Data from the LUMEN Registry - Beyond the Abstract

Testicular Cancer

Persistent Suicide Risk in Survivors of Testicular Cancer: A Population-Based Cohort Study - Beyond the Abstract

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