PSMA-Guided Ablation of the Prostate: A Multicenter Randomized Controlled Trial


Condition: Prostate Cancer, Localized Prostate Carcinoma

Study Type: Interventional

Clinical Trials Identifier NCT 8-digits: NCT06003556

Sponsor: University of Alberta

Phase: Phase 2

Eligibility:

  • Age: minimum 50 Years maximum N/A
  • Gender: Male

Inclusion Criteria:

  1. Age > 50
  2. Clinical stage < T2b
  3. PSA < 15
  4. Combined targeted and systematic MRI-guided biopsy shows unilateral Gleason Grade Group 2 or 3 prostate cancer

Exclusion Criteria:

  1. Unable to obtain consent
  2. Weight >250 kg (weight limitation of scanners)
  3. Unable to lie flat for 30 minutes to complete the PET imaging
  4. Lack of intravenous access
  5. eGFR < 40 mL/min/1.73 m2 and/or a history of a severe reaction to CT contrast
  6. Prior androgen deprivation therapy or radiation therapy to prostate gland

View trial on ClinicalTrials.gov