Clinical Trials
26 results for Kidney/Renal Cancer
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
- Condition: Bile Duct Cancer, Gall Bladder Cancer, Breast Cancer, Neuroendocrine Tumors, Ovarian Cancer, Pancreatic Adenocarcinoma, Soft Tissue Sarcoma, Vulvar Cancer, Prostate Cancer
- Study ID: NCT05000294
An Open-label Phase 1/2 Study to Evaluate the Safety, Biological Response and Efficacy of a Single Dose of Temferon (autologous CD34+-enriched Hematopoietic Stem and Progenitors Cells Genetically Modified with Human Interferon-α2) in Patients with Metasta
- Condition: Clear Cell RCC
- Study ID: NCT06716853
Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma
- Condition: Ivonescimab, Clear Cell Renal Carcinoma
- Study ID: NCT06940518
Phase II Trial of Neoadjuvant Immune-based Combinations in Patients Undergoing Nephrectomy for Locally Advanced ccRCC
- Condition: Neoplasms, Kidney Neoplasms, Urologic Neoplasms, Urogenital Neoplasms, Female Urogenital Diseases, Urogenital Diseases, Kidney Diseases, Urologic Diseases, Male Urogenital Diseases, Carcinoma, Carcinoma, Renal Cell, Antineoplastic Agents, Immu
- Study ID: NCT06114940
A Pilot Phase II Study of Neoadjuvant Cemiplimab + Fianlimab in Patients With Locally Advanced Clear Cell Renal Cell Carcinoma Undergoing Nephrectomy
- Condition: Renal Cell Carcinoma
- Study ID: NCT06699602
A Phase 1b/2 Study of Abemaciclib Plus Cabozantinib in Immune Checkpoint Blockade-pretreated Metastatic Clear Cell Renal Cell Carcinoma
- Condition: Metastatic Renal Cell Carcinoma, Translocation Renal Cell Carcinoma
- Study ID: NCT06835972
Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma: The CANIQOL Multicentre Study
- Condition: Renal Cell Carcinoma (Kidney Cancer), Metastatic Renal Cell Carcinoma, Locally Advanced
- Study ID: NCT07028125
A Phase II, Open-label, Single-arm Study of nEoadjuvant Zanzalintinib (XL092) Plus nivoLumab in Patients With lOcally Advanced and/or inopeRable clEar Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis (EXPLORE-RCC)
- Condition: Locally Advanced Renal Cell Carcinoma
- Study ID: NCT06794229
A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
- Condition: Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma
- Study ID: NCT07011719
Phase 2/3 Open-Label Multicenter Study to Assess the Diagnostic Performance of Piflufolastat F 18 PET/CT on Intended Clinical Management in Patients With Suspected, or at High Risk for Metastatic ccRCC
- Condition: Clear Cell Renal Cell Carcinoma
- Study ID: NCT07084909
A Phase 1b Study to Assess the Effects of Belzutifan on 89Zr-DFO-girentuximab Uptake as a Surrogate to Determine CAIX Tumor Expression in Patients With Clear Cell Renal Cell Carcinoma
- Condition: Metastatic Clear Cell Renal Cell Carcinoma
- Study ID: NCT07179770
Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE)
- Condition: Clear Cell Renal Cell Carcinoma
- Study ID: NCT07187778
A Phase 1/1b Open-label, Multi-center Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)
- Condition: Renal Cell Carcinoma
- Study ID: NCT07195682
An Open-Label, First-in-Human, Phase 1/2 Dose Escalation and Expansion Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma
- Condition: Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma, RCC, Clear Cell Renal Cell Carcinoma Metastatic, ccRCC, VHL-Associated Clear Cell Renal Cell Carcinoma, VHL-Associated Renal Cell Carcinoma, Kidney Cancer Metastatic, Kidney Cancers
- Study ID: NCT07300241
A Randomized Phase II Trial of Cemiplimab or Cemiplimab and Fianlimab After Stereotactic Body Radiotherapy in Oligo-Metastatic Clear Cell Renal Cell Carcinoma
- Condition: Clear Cell Renal Cell Carcinoma
- Study ID: NCT07223541
PRE-surgical NEOadjuvant Sandwich Immunotherapy With HIF inhibiTion in Renal Cell Carcinoma (PRENEOSHIFT-RCC)
- Condition: Renal Cell Carcinoma, Kidney Cancer, Kidney Neoplasm, Renal Carcinoma
- Study ID: NCT07397611
An Open-label, Randomized Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of the Combination Therapy of SLC-3010 and Axitinib Compared to Axitinib Monotherapy as a Second-line Treatment for Locally Advanced or Metastatic Clear Cell Renal Cell C
- Condition: Clear Cell Renal Cell Carcinoma, Neoplasms, Malignant Neoplasms, Malignant Neoplasm of Kidney, Except Renal Pelvis
- Study ID: NCT07469683
CAIX PET/ CT Guided Radiation Therapy in CcRCC.
- Condition: Radiation Therapy, Metastatic Renal Cancer, Recurrent Renal Cell Cancer
- Study ID: NCT07540260
An Open-Label, Multicenter, Phase 1/2 Study of Allogeneic Dual-target CD70/CAIX (CA9) Chimeric Antigen Receptor Natural Killer Cells in Adults With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
- Condition: Advanced or Metastatic Clear Cell Renal Cell Carcinoma
- Study ID: NCT07551349
Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)
- Condition: Active Surveillance, Clear Cell Renal Cell Carcinoma
- Study ID: NCT07023432
68Ga-NYM096 PET/ CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Complex Cystic Renal Leision
- Condition: ccRCC, Complex Renal Cyst
- Study ID: NCT06949215
Phase II Trial Evaluating the Efficacy of 177Lutetium-PSMA-617 Treatment in Patients With Metastatic Clear Cell Renal Carcinoma Cell With Progressive Disease on First-line or Second-line Systemic Treatment
- Condition: Metastatic Clear Cell Renal Cell Carcinoma
- Study ID: NCT06783348
A Phase II Study of Neoadjuvant Ivonescimab in Patients With High-Risk, Localized RCC
- Condition: Localized Clear Cell Renal Cell Carcinoma, Resectable Clear Cell Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
- Study ID: NCT07226544
Phase III Double Blinded Trial of Immune-Based Therapy With a Live Biotherapeutic MO-03 or Placebo for Frontline Therapy of Advanced Clear Cell Renal Cell Carcinoma [BioFront Trial]
- Condition: Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
- Study ID: NCT07383441
A Clinical Study to Evaluate the Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Patients With Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
- Condition: Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
- Study ID: NCT07645690
A Phase II Trial of CD70-Targeted Immuno-PET/CT-Directed Treatment Holiday for Metastatic Clear Cell Renal Cell Carcinoma With IMDC Favorable or Intermediate Risk
- Condition: Metastatic Clear Cell Renal Cell Carcinoma
- Study ID: NCT07615348