Clinical Trials
45 results for Kidney/Renal Cancer
A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma
- Condition: Renal Cell Carcinoma
- Intervention: Device: CyberKnife
- Study ID: NCT01890590
Kidney Cancer DNA Registry
- Condition: Renal Cancer
- Intervention: Other: salvia for germline DNA, Behavioral: the Kidney Cancer Questionnaire, Behavioral: Family History Questionnaire (when applicable)
- Study ID: NCT02087852
Phase II Study: Stereotactic Ablative Radiotherapy for Renal Tumors
- Condition: Renal Tumor
- Intervention: Radiation: Stereotactic Ablative Radiotherapy
- Study ID: NCT03747133
Phase II Trial of AZD6738 Alone and in Combination With Olaparib in Patients With Selected Solid Tumor Malignancies
- Condition: Clear Cell Renal Cell Carcinoma, Locally Advance Pancreatic Ductal Adenocarcinoma, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Metastatic Renal Cell Carcinoma, Metastatic Urothelial Carcinoma, Pancreatic Ductal Ad
- Study ID: NCT03682289
An International Investigator-led Phase III Multi Arm Multi Stage Multi-centre Randomised Controlled Platform Trial of Adjuvant Therapy in Patients With Resected Primary Renal Cell Carcinoma (RCC) at High or Intermediate Risk of Relapse
- Condition: Renal Cell Carcinoma
- Intervention: Drug: Durvalumab, Drug: Tremelimumab
- Study ID: NCT03288532
Genetic Evaluation of Renal Cell Carcinoma; Predicting Biomarkers for Renal Cell Carcinoma
- Condition: Kidney Cancer
- Study ID: NCT03414827
Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma
- Condition: Renal Cell Carcinoma
- Study ID: NCT06053658
Phase 2, Open-label, Two Cohort, Multicenter Trial for Sequential Treatment of High Dose Cabozantinib or Cabozantinib Plus Nivolumab on/After Progression on Cabozantinib Monotherapy in Advanced Renal Cell Carcinoma (Seq-Cabo)
- Condition: RCC, Renal Cell Carcinoma
- Study ID: NCT05931393
Comparison of Outcomes of Multiple Platforms for Assisted Robotic-Kidney
- Condition: Renal Carcinoma
- Study ID: NCT06290427
A Prospective, Open-label, Single-center Study of CD70-Specific PET/CT Imaging for Non-invasive Diagnosis of Renal Cell Carcinoma
- Condition: RCC, Renal Cell Cancer
- Study ID: NCT06769893
A Study on the Safety and Efficacy of Super-selective Tumour Arterial Embolisation in Combination With Toripalimab and Axitinib as a Preoperative Treatment for Advanced Renal Cell Carcinoma
- Condition: Renal Cell Carcinoma (RCC)
- Study ID: NCT07172386
"Embolization Before Ablation of Renal Cell Carcinoma (EMBARC)"
- Condition: Renal Cell Carcinoma (RCC)
- Study ID: NCT05410509
Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT
- Condition: Carcinoma, Renal Cell, Diagnostic Imaging, Pathology, Deep Learning
- Study ID: NCT07166445
An Open-label, Multicenter, Dose Escalation and Expansion Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics, and Anti-tumor Activity of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as a Single Agent in Patients Wit
- Condition: Advanced Solid Tumor, Metastatic Solid Tumor, Non-small Cell Lung Cancer (NSCLC), Head and Neck (HNSCC), Pancreatic Cancer, Renal Cell Carcinoma (RCC)
- Study ID: NCT07172802
Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial, From 2025 to 2027
- Condition: RCC, Renal Cell Cancer
- Study ID: NCT07190638
Characterizing the Tumor-draining Lymph Nodes and Other Immune Sites in Renal Cell Carcinoma
- Condition: Renal Cell Carcinoma (RCC)
- Study ID: NCT07038733
Cabozantinib and Nivolumab Among Older Patients With Renal-cell Carcinoma, a Prospective Cohort With Geriatric, Pharmacologic and Patient-reported-outcome Evaluation
- Condition: Kidney Cancer, Renal Cell Cancer
- Study ID: NCT06934057
Indocyanine Green (ICG) Guided Tumor Resection
- Condition: Neoplastic Disease, Solid Tumor
- Study ID: NCT04084067
Clinical Study of CD70-Targeted Chimeric Antigen Receptor T Lymphocytes (CAR-T) in Advanced CD70-Positive Malignant Solid Tumors
- Condition: Renal Cell Carcinoma (RCC), Lung Cancer, Anaplastic Thyroid Carcinomas, Ovarian Cancer, Cervical Cancer, Thymic Carcinoma
- Study ID: NCT07181720
Efficacy of Ropivacaine Epinephrine Clonidine Ketorolac (R.E.C.K) vs Exparel in Robotic Nephrectomy: a Randomized, Prospective Trial
- Condition: Renal Carcinoma, Nephrectomy / Methods, Pain Management
- Study ID: NCT07092566
Standard Flank Approach vs Supine Approach for Robot-assisted Partial Nephrectomy: a Randomized Clinical Trial
- Condition: Kidney Neoplasm
- Study ID: NCT07234409
A Multicenter, Randomized, Double-Blind, Parallel-Controlled Phase I Clinical Study to Evaluate the Pharmacokinetic Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® (US-sourced Keytruda®) in Multiple Resected Solid Tumors
- Condition: Non-small Cell Lung Cancer, Melanoma, Renal Cell Carcinoma
- Study ID: NCT07160335
Patient-partnered Research: a Key to Investigating Fear of Cancer Recurrence in Patients With Surgically Treated Kidney Cancer (PP-RECURK)
- Condition: Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
- Study ID: NCT07234656
Effectiveness of a Personalized 6-month Programme on Frailty in Older Patients Treated for Bladder or Kidney Cancer - FRAGECO - Multicenter, Controlled, Randomized Study
- Condition: Bladder (Urothelial, Transitional Cell) Cancer, Kidney (Renal Cell) Cancer
- Study ID: NCT07073703
Observational Study on the Abscopal Efect by Ultra-hypofractionated Radiation Therapyin Combination With Immune Checkpoint Inhibiters for Metastatic Renal Cell Carcinoma
- Condition: Renal Cell Cancer Metastatic
- Study ID: NCT07240610
Study on the Diagnostic Value of Novel PET Molecular Imaging for Renal Cell Carcinoma
- Condition: Renal Cell Carcinoma
- Study ID: NCT07301827
A Prospective Clinical Study on the Predictive Value of CEUS and Super-resolution Imaging Technology for Renal Function Outcome in Patients After Partial or Radical Nephrectomy
- Condition: Nephrectomy, Renal Cell Cancer, AKI - Acute Kidney Injury
- Study ID: NCT07294859
A Phase 1b/2 Study Evaluating the Safety and Preliminary Efficacy of OM-RCA-01, an Anti-FGFR1 Monoclonal Antibody, in Patients With Metastatic Cancers Expressing FGFR1.
- Condition: Renal Cell Carcinoma Metastatic, Prostate Cancer Metastatic, Non-small Cell Lung Cancer Metastatic, Breast Cancer Metastatic, Head & Neck Cancer
- Study ID: NCT07292168
The Impact of Cold Ischemia on Recovery From Ischemia After Robot-assisted Partial Nephrectomy: A Randomized Controlled Clinical Study
- Condition: Renal Cell Carcinoma, Renal Function Abnormal
- Study ID: NCT07326280
A Randomized Study of Nivolumab and Ipilimumab With and Without EXL01 in First-Line Treatment of Metastatic Renal Cell Carcinoma (mRCC)
- Condition: Advanced Clear Cell Renal Cell Carcinoma, Advanced Sarcomatoid Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Sarcomatoid Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
- Study ID: NCT07128680
AN INTERVENTIONAL PHASE 1B/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF PF-08634404 MONOTHERAPY AND IN COMBINATION WITH OTHER ANTICANCER AGENTS IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC RENAL CELL CARCINOMA
- Condition: Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma, Renal Cancer, Renal Neoplasm, Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Clear-cell Metastatic Renal Cell Carcinoma, Carcinoma, Renal Cell Metastasis, Advanced or Metasta
- Study ID: NCT07227415
A Randomized Phase 2 Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)
- Condition: Advanced Renal Cell Carcinoma (aRCC), Metastatic Renal Cell Carcinoma ( mRCC), Clear Cell Renal Cell Carcinoma (ccRCC)
- Study ID: NCT07188896
Phase II Single-arm Clinical Study of the Efficacy and Safety of Pucotenlimab in Combination With Vorolanib Neoadjuvant Therapy for Patients With High-risk Renal Carcinoma Indicating Partial Nephrectomy
- Condition: Vorolanib, Clear Cell Renal Cell Carcinoma (ccRCC), Neoadjuvant Therapy
- Study ID: NCT07386158
The Efficacy and Safety of Iparomlimab and Tuvonralimab (QL1706) Combined With Lenvatinib as Neoadjuvant Therapy in Renal Cancer With Partial Nephrectomy Indications But High Surgical Risk：A Single Arm, Phase II Clinical Study
- Condition: Iparomlimab and Tuvonralimab, Clear Cell Renal Cell Carcinoma, Neoadjuvant Therapy
- Study ID: NCT07389629
Targeted Decision Making In Renal Cell Carcinoma Relying on a Radiogenomics Translational Platform
- Condition: Renal Tumors
- Study ID: NCT06868927
A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)
- Condition: Phase 1b, HC-7366, SHARK, Kidney Cancer
- Study ID: NCT07401875
Organ Sparing Marker-less CBCT-guided Stereotactic Adaptive Radiotherapy for Primary Non-metastasized Renal Tumors
- Condition: Renal Cell Carcinoma (RCC)
- Study ID: NCT07402109
Emulated-target Trial for Guiding Stratified Treatment for Renal Cell Carcinoma With Venous Tumor Thrombus
- Condition: Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC), Tumor Thrombus, Prognosis, Prognostic Cancer Model, Real World Study, Observational Study
- Study ID: NCT07117227
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
- Condition: Type 2 Diabetes
- Study ID: NCT07546929
Pilot Study Assessment of Bone Mineral Density Changes During Treatment With Anti-PD-1 Immunotherapy Agents
- Condition: Breast Cancer (Triple Negative Breast Cancer (TNBC)), Renal Cell Carcinoma (Kidney Cancer), Melanoma (Skin Cancer), Non-Small Cell Lung Cancer, MSI-H/dMMR Rectal Cancer, Squamous Cell Carcinoma Mouth, Invasive Mammary Carcinoma, Classic Hodgkin Lym
- Study ID: NCT07555210
Impact of Microbiome Modulation With CBM588 in Combination With Pembrolizumab for Adjuvant Therapy of High-Risk, Resected Renal Cell Carcinoma (RCC)
- Condition: Clear Cell Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Stage II Renal Cell Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
- Study ID: NCT07037004
Assessment of Quality of Life and Outcomes in Patients Treated With Stereotactic Body Radiotherapy (SBRT) for Inoperable Renal Cell Carcinoma (RCC): A Multicenter Phase II Study
- Condition: Renal Cell Carcinoma
- Study ID: NCT05023265
A Prospective, Open-label, Phase II Clinical Trial of Perioperative Toripalimab Plus Lenvatinib for Multi-stage Clear Cell Renal Cell Carcinoma (ccRCC)
- Condition: Clear Cell RCC
- Study ID: NCT07571551
Evaluation of Diagnostic Value of 18F-T2 PET/ CT Imaging for Tumors Likely to Express High Levels of CAIX
- Condition: Clear Cell Renal Cell Cancer (ccRCC), Urothelial Carcinoma (UC), Colorectal Cancer, Cervical Cancer, Ovarian Cancer, Head and Neck Cancer, Hepatocellular Carcinoma (HCC), Cholangiocarcinoma, Non Small Cell Lung Cancer, Small Cell Lung Cancer, Br
- Study ID: NCT07557225
Clinical Application of CAIX-Targeted PET Imaging in Tumors
- Condition: Kidney Cancers
- Study ID: NCT07590310