Condition: Oncology

Study Type: Interventional

Clinical Trials Identifier NCT 8-digits: NCT07680556

Sponsor: Radboud University Medical Center

Eligibility:

• Age: minimum 18 Years maximum N/A
• Gender: All

Inclusion Criteria:

• Age ≥18 years.
• Diagnosed with advanced RCC with indication for standard-of-care dual ICI treatment.
• Able and willing to give written informed consent.

Exclusion Criteria:

• Life expectancy <6 months.
• Unable to perform basic activities of daily living such as walking.
• Presence of cognitive impairment or severe emotional instability (e.g. schizophrenia, Alzheimer's disease, alcohol addiction), at the discretion of the investigator.
• Presence of other disabling comorbidities that may interfere with the ability to perform physical exercise (e.g., heart failure, chronic obstructive pulmonary disease (COPD, GOLD stage 3 or 4), orthopaedic conditions, or neurological disorders such as hernia, paresis, amputation or active rheumatoid arthritis), at the discretion of the investigator.
• Current participation in structured vigorous aerobic and/or resistance exercise ≥ 2 times per week at a level comparable to the intervention

View trial on ClinicalTrials.gov