PD-Inhibitor (Nivolumab) and Ipilimumab Followed by Nivolumab vs. VEGF TKI Cabozantinib With Nivolumab: A Phase III Trial in Metastatic Untreated Renal Cell Cancer [PDIGREE]


Condition: Clear Cell Renal Cell Carcinoma, Metastatic Malignant Neoplasm in Lymph Node, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Soft Tissues, Metastatic Malignant Neoplasm in the Viscera, Sarcomatoid Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8

Intervention:

  • Drug: Cabozantinib
  • Biological: Ipilimumab
  • Biological: Nivolumab
  • Other: Quality-of-Life Assessment
  • Other: Questionnaire Administration

Purpose: This phase III trial compares the usual treatment (treatment with ipilimumab and nivolumab followed by nivolumab alone) to treatment with ipilimumab and nivolumab, followed by nivolumab with cabozantinib in patients with untreated renal cell carcinoma that has spread to other parts of the body. The addition of cabozantinib to the usual treatment may make it work better. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as cabozantinib, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known how well the combination of cabozantinib and nivolumab after initial treatment with ipilimumab and nivolumab works in treating patients with renal cell cancer that has spread to other parts of the body.

Study Type: Interventional

Clinical Trials Identifier NCT 8-digits: NCT03793166

Sponsor: National Cancer Institute (NCI)

Primary Outcome Measures:

  • Measure: Overall survival (OS)
  • Time Frame: From registration to date of death from any cause for non-randomized patients, from time of randomization until death from any cause for randomized patients, assessed up to 5 years
  • Safety Issue:

Secondary Outcome Measures:

  • Measure: Progression-free survival (PFS)
  • Time Frame: From date of registration to date of progression or death from any cause, whichever occurs first, assessed up to 5 years
  • Safety Issue:
  • Measure: Complete response (CR) (randomized patients)
  • Time Frame: At 12 months from date of randomization
  • Safety Issue:
  • Measure: Objective response
  • Time Frame: Up to 5 years
  • Safety Issue:
  • Measure: Proportion of patients who discontinue protocol-directed treatment prior to 1 year from date of study registration
  • Time Frame: Up to 5 years
  • Safety Issue:
  • Measure: Incidence of adverse events
  • Time Frame: Up to 5 years
  • Safety Issue:

Estimated Enrollment: 1046

Study Start Date: May 9, 2019

Phase: Phase 3

Eligibility:

  • Age: minimum 18 Years maximum N/A
  • Gender: All

Inclusion Criteria:

  • STEP I REGISTRATION CRITERIA
  • Histologically documented renal cell carcinoma with clear cell component, including patients who have sarcomatoid features.
  • Any metastatic disease, including visceral, lymph node, other soft tissue and bone, measurable per RECIST 1.1.
  • Measurable disease as defined in the protocol.
  • Intermediate or poor risk patients per International Metastatic Renal Cell Carcinoma Database (IMDC) criteria will be eligible (1 or more of the following: Karnofsky performance status (KPS) < 80, < 1 year from diagnosis to systemic treatment, hemoglobin less than lower limit of normal (LLN), corrected calcium concentration greater than upper limit of normal [ULN], absolute neutrophil count greater than ULN, platelet count > ULN).
  • Central nervous system (CNS) disease permitted, if stable and not otherwise causing symptoms or needing active treatment.
  • Karnofsky performance status >= 70%.
  • No prior treatment with PD-1, PD-L1, or CTLA-4 targeting agents (including but not limited to nivolumab, pembrolizumab, pidilizumab, durvalumab, atezolizumab, tremelimumab, and ipilimumab), or any other drug or antibody specifically targeting T-cell co-stimulation or checkpoint pathways.
  • No prior previous systemic therapy for renal cell carcinoma (prior HD IL-2 [> 28 days] and prior adjuvant sunitinib > 180 days since completion are allowed).
  • No cancer therapy less than 28 days prior to registration; this includes radiation therapy, except for bone lesions less than 14 days prior to registration. There must be a complete recovery and no ongoing complications from radiotherapy.
  • Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects. Therefore, for women of childbearing potential only, a negative serum or urine pregnancy test done =< 14 days prior to registration is required.
  • Absolute neutrophil count (ANC) >= 1,500/mm^3.
  • Platelet Count >= 100,000/mm^3.
  • Hemoglobin >= 8 g/dL.
  • Calculated (Calc.) creatinine clearance >= 30 mL/min.
  • Urine protein =< 1+ or urine protein to creatinine (UPC) ratio < 1.
  • Total Bilirubin =< 1.5 x upper limit of normal (ULN).
  • Aspartate aminotransferase/alanine aminotransferase (AST/ALT) =< 2.5 x upper limit of normal (ULN) or < 5 x ULN if hepatic metastases present.
  • STEP 2 REGISTRATION

Eligibility Criteria:

  • Successful completion of at least 1 cycle of ipilimumab/nivolumab.
  • Resolution of any treatment-related adverse events to grade 1 or less per dose modification section.
  • No more than 56 days from last dose of ipilimumab/nivolumab.

Exclusion Criteria:

  • Active autoimmune disease requiring ongoing therapy.
  • Ongoing acute toxicity > grade 2 from previous treatment.
  • History of severe allergic, anaphylactic or other hypersensitivity reactions to chimeric or humanized antibodies.
  • History of human immunodeficiency virus (HIV) or active hepatitis B/C, or tuberculosis.
  • Concurrent use of immunosuppressive medication including prednisone above 10 mg daily.
  • Uncontrolled adrenal insufficiency.
  • Uncontrolled hypertension (systolic blood pressure [BP] >150 mmHg or diastolic BP > 90 mmHg).
  • Major surgery less than 28 days prior to registration.
  • Any serious non-healing wound, ulcer, or bone fracture within 28 days prior to registration.
  • Any arterial thrombotic events within 180 days prior to registration.
  • Clinically significant hematuria, hematemesis, or hemoptysis within 12 weeks prior to registration.
  • Cavitating pulmonary lesions or known endotracheal or endobronchial disease manifestations.
  • Lesions encasing or invading any major blood vessels.
  • Moderate of severe hepatic impairment (Child-Pugh B or C).
  • Any history of untreated pulmonary embolism or deep venous thrombosis (DVT) in the 180 days prior to registration. (Any asymptomatic, treated pulmonary embolism or asymptomatic, treated deep venous thrombosis > 30 days prior to registration allowed).
  • Corrected QT interval calculated by the Fridericia formula (QTcF) > 500 ms.
  • Unstable cardiac arrhythmia within 6 months prior to registration.
  • Any gastrointestinal (GI) bleeding =< 180 days, hemoptysis, or other signs of pulmonary hemorrhage =< 90 days prior to registration.
  • History of abdominal fistula, gastrointestinal perforation, intra-abdominal abscess, bowel obstruction, or gastric outlet obstruction within 180 days prior to registration.
  • Active peptic ulcer disease, inflammatory bowel disease, or malabsorption syndrome within 28 days prior to registration.
  • Untreated hypothyroidism, evidence of pancreatitis, history of organ transplant, or history of congenital QT syndrome.
  • Active treatment with warfarin or any oral factor Xa inhibitors (treatment with low molecular weight heparin [LMWH] is allowed).
  • Significant cardiac ischemia events (ST elevation myocardial infarction [STEMI] or non-ST elevation myocardial infarction [NSTEMI]) within 6 months or active NY Heart Association class 3-4 heart failure symptoms

Locations:

  • Anchorage Associates in Radiation Medicine
  • Anchorage Alaska 98508 United States
  • Anchorage Radiation Therapy Center
  • Anchorage Alaska 99504 United States
  • Alaska Breast Care and Surgery LLC
  • Anchorage Alaska 99508 United States
  • Alaska Oncology and Hematology LLC
  • Anchorage Alaska 99508 United States
  • Alaska Women's Cancer Care
  • Anchorage Alaska 99508 United States
  • Anchorage Oncology Centre
  • Anchorage Alaska 99508 United States
  • Katmai Oncology Group
  • Anchorage Alaska 99508 United States
  • Providence Alaska Medical Center
  • Anchorage Alaska 99508 United States
  • Fairbanks Memorial Hospital
  • Fairbanks Alaska 99701 United States
  • Kingman Regional Medical Center
  • Kingman Arizona 86401 United States
  • Mercy Hospital Fort Smith
  • Fort Smith Arkansas 72903 United States
  • CHI Saint Vincent Cancer Center Hot Springs
  • Hot Springs Arkansas 71913 United States
  • Kaiser Permanente-Anaheim
  • Anaheim California 92806 United States
  • PCR Oncology
  • Arroyo Grande California 93420 United States
  • Kaiser Permanente-Baldwin Park
  • Baldwin Park California 91706 United States
  • Kaiser Permanente-Bellflower
  • Bellflower California 90706 United States
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center
  • Burbank California 91505 United States
  • Community Cancer Institute
  • Clovis California 93611 United States
  • University Oncology Associates
  • Clovis California 93611 United States
  • Kaiser Permanente-Fontana
  • Fontana California 92335 United States
  • Kaiser Permanente - Harbor City
  • Harbor City California 90710 United States
  • Kaiser Permanente-Irvine
  • Irvine California 92618 United States
  • UC San Diego Moores Cancer Center
  • La Jolla California 92093 United States
  • Kaiser Permanente Los Angeles Medical Center
  • Los Angeles California 90027 United States
  • Kaiser Permanente-Cadillac
  • Los Angeles California 90034 United States
  • Kaiser Permanente - Panorama City
  • Panorama City California 91402 United States
  • Kaiser Permanente-Riverside
  • Riverside California 92505 United States
  • Kaiser Permanente-San Diego Mission
  • San Diego California 92108 United States
  • Kaiser Permanente-San Diego Zion
  • San Diego California 92120 United States
  • Naval Medical Center -San Diego
  • San Diego California 92134 United States
  • Kaiser Permanente-San Marcos
  • San Marcos California 92078 United States
  • Kaiser Permanente-Woodland Hills
  • Woodland Hills California 91367 United States
  • Rocky Mountain Cancer Centers-Aurora
  • Aurora Colorado 80012 United States
  • The Medical Center of Aurora
  • Aurora Colorado 80012 United States
  • University of Colorado Hospital
  • Aurora Colorado 80045 United States
  • Boulder Community Hospital
  • Boulder Colorado 80301 United States
  • Rocky Mountain Cancer Centers-Boulder
  • Boulder Colorado 80304 United States
  • Penrose-Saint Francis Healthcare
  • Colorado Springs Colorado 80907 United States
  • Rocky Mountain Cancer Centers-Penrose
  • Colorado Springs Colorado 80907 United States
  • UCHealth Memorial Hospital Central
  • Colorado Springs Colorado 80909 United States
  • Memorial Hospital North
  • Colorado Springs Colorado 80920 United States
  • Cancer Center of Colorado at Sloan's Lake
  • Denver Colorado 80204 United States
  • National Jewish Health-Main Campus
  • Denver Colorado 80206 United States
  • The Women's Imaging Center
  • Denver Colorado 80209 United States
  • Porter Adventist Hospital
  • Denver Colorado 80210 United States
  • Colorado Blood Cancer Institute
  • Denver Colorado 80218 United States
  • Presbyterian - Saint Lukes Medical Center - Health One
  • Denver Colorado 80218 United States
  • Rocky Mountain Cancer Centers-Midtown
  • Denver Colorado 80218 United States
  • SCL Health Saint Joseph Hospital
  • Denver Colorado 80218 United States
  • Rocky Mountain Cancer Centers-Rose
  • Denver Colorado 80220 United States
  • Rose Medical Center
  • Denver Colorado 80220 United States
  • Western Surgical Care
  • Denver Colorado 80220 United States
  • Mercy Medical Center
  • Durango Colorado 81301 United States
  • Southwest Oncology PC
  • Durango Colorado 81301 United States
  • Mountain Blue Cancer Care Center - Swedish
  • Englewood Colorado 80113 United States
  • Swedish Medical Center
  • Englewood Colorado 80113 United States
  • Poudre Valley Hospital
  • Fort Collins Colorado 80524 United States
  • Cancer Care and Hematology-Fort Collins
  • Fort Collins Colorado 80528 United States
  • National Jewish Health-Western Hematology Oncology
  • Golden Colorado 80401 United States
  • Saint Mary's Hospital and Regional Medical Center
  • Grand Junction Colorado 81501 United States
  • North Colorado Medical Center
  • Greeley Colorado 80631 United States
  • UCHealth Greeley Hospital
  • Greeley Colorado 80631 United States
  • UCHealth Highlands Ranch Hospital
  • Highlands Ranch Colorado 80129 United States
  • Good Samaritan Medical Center
  • Lafayette Colorado 80026 United States
  • Saint Anthony Hospital
  • Lakewood Colorado 80228 United States
  • Rocky Mountain Cancer Centers-Littleton
  • Littleton Colorado 80120 United States
  • Littleton Adventist Hospital
  • Littleton Colorado 80122 United States
  • Rocky Mountain Cancer Centers-Sky Ridge
  • Lone Tree Colorado 80124 United States
  • Sky Ridge Medical Center
  • Lone Tree Colorado 80124 United States
  • UCHealth Lone Tree Health Center
  • Lone Tree Colorado 80124 United States
  • Longmont United Hospital
  • Longmont Colorado 80501 United States
  • Rocky Mountain Cancer Centers-Longmont
  • Longmont Colorado 80501 United States
  • Medical Center of the Rockies
  • Loveland Colorado 80538 United States
  • McKee Medical Center
  • Loveland Colorado 80539 United States
  • Parker Adventist Hospital
  • Parker Colorado 80138 United States
  • Saint Mary Corwin Medical Center
  • Pueblo Colorado 81004 United States
  • National Jewish Health-Northern Hematology Oncology
  • Thornton Colorado 80260 United States
  • SCL Health Lutheran Medical Center
  • Wheat Ridge Colorado 80033 United States
  • Stamford Hospital/Bennett Cancer Center
  • Stamford Connecticut 06904 United States
  • Beebe Medical Center
  • Lewes Delaware 19958 United States
  • Delaware Clinical and Laboratory Physicians PA
  • Newark Delaware 19713 United States
  • Helen F Graham Cancer Center
  • Newark Delaware 19713 United States
  • Medical Oncology Hematology Consultants PA
  • Newark Delaware 19713 United States
  • Christiana Care Health System-Christiana Hospital
  • Newark Delaware 19718 United States
  • Beebe Health Campus
  • Rehoboth Beach Delaware 19971 United States
  • Nanticoke Memorial Hospital
  • Seaford Delaware 19973 United States
  • Christiana Care Health System-Wilmington Hospital
  • Wilmington Delaware 19801 United States
  • George Washington University Medical Center
  • Washington District of Columbia 20037 United States
  • Holy Cross Hospital
  • Fort Lauderdale Florida 33308 United States
  • UF Cancer Center at Orlando Health
  • Orlando Florida 32806 United States
  • Northside Hospital
  • Atlanta Georgia 30342 United States
  • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
  • Savannah Georgia 31405 United States
  • Hawaii Cancer Care - Savio
  • 'Aiea Hawaii 96701 United States
  • Hawaii Oncology Inc-Pali Momi
  • 'Aiea Hawaii 96701 United States
  • Pali Momi Medical Center
  • 'Aiea Hawaii 96701 United States
  • The Cancer Center of Hawaii-Pali Momi
  • 'Aiea Hawaii 96701 United States
  • Hawaii Cancer Care Inc-POB II
  • Honolulu Hawaii 96813 United States
  • Hawaii Oncology Inc-POB I
  • Honolulu Hawaii 96813 United States
  • Island Urology
  • Honolulu Hawaii 96813 United States
  • Queen's Medical Center
  • Honolulu Hawaii 96813 United States
  • Straub Clinic and Hospital
  • Honolulu Hawaii 96813 United States
  • University of Hawaii Cancer Center
  • Honolulu Hawaii 96813 United States
  • Hawaii Oncology Inc-Kuakini
  • Honolulu Hawaii 96817 United States
  • The Cancer Center of Hawaii-Liliha
  • Honolulu Hawaii 96817 United States
  • Kapiolani Medical Center for Women and Children
  • Honolulu Hawaii 96826 United States
  • Wilcox Memorial Hospital and Kauai Medical Clinic
  • Lihue Hawaii 96766 United States
  • Saint Alphonsus Cancer Care Center-Boise
  • Boise Idaho 83706 United States
  • Saint Luke's Mountain States Tumor Institute
  • Boise Idaho 83712 United States
  • Saint Alphonsus Cancer Care Center-Caldwell
  • Caldwell Idaho 83605 United States
  • Kootenai Medical Center
  • Coeur d'Alene Idaho 83814 United States
  • Walter Knox Memorial Hospital
  • Emmett Idaho 83617 United States
  • Saint Luke's Mountain States Tumor Institute - Fruitland
  • Fruitland Idaho 83619 United States
  • Idaho Urologic Institute-Meridian
  • Meridian Idaho 83642 United States
  • Saint Luke's Mountain States Tumor Institute - Meridian
  • Meridian Idaho 83642 United States
  • Saint Alphonsus Medical Center-Nampa
  • Nampa Idaho 83686 United States
  • Saint Luke's Mountain States Tumor Institute - Nampa
  • Nampa Idaho 83686 United States
  • Kootenai Cancer Center
  • Post Falls Idaho 83854 United States
  • Kootenai Cancer Clinic
  • Sandpoint Idaho 83864 United States
  • Saint Luke's Mountain States Tumor Institute-Twin Falls
  • Twin Falls Idaho 83301 United States
  • Rush - Copley Medical Center
  • Aurora Illinois 60504 United States
  • Illinois CancerCare-Bloomington
  • Bloomington Illinois 61704 United States
  • Illinois CancerCare-Canton
  • Canton Illinois 61520 United States
  • Memorial Hospital of Carbondale
  • Carbondale Illinois 62902 United States
  • SIH Cancer Institute
  • Carterville Illinois 62918 United States
  • Illinois CancerCare-Carthage
  • Carthage Illinois 62321 United States
  • Centralia Oncology Clinic
  • Centralia Illinois 62801 United States
  • Northwestern University
  • Chicago Illinois 60611 United States
  • University of Chicago Comprehensive Cancer Center
  • Chicago Illinois 60637 United States
  • Carle on Vermilion
  • Danville Illinois 61832 United States
  • Cancer Care Specialists of Illinois - Decatur
  • Decatur Illinois 62526 United States
  • Decatur Memorial Hospital
  • Decatur Illinois 62526 United States
  • Northwestern Medicine Cancer Center Kishwaukee
  • DeKalb Illinois 60115 United States
  • Illinois CancerCare-Dixon
  • Dixon Illinois 61021 United States
  • Carle Physician Group-Effingham
  • Effingham Illinois 62401 United States
  • Crossroads Cancer Center
  • Effingham Illinois 62401 United States
  • Illinois CancerCare-Eureka
  • Eureka Illinois 61530 United States
  • Illinois CancerCare-Galesburg
  • Galesburg Illinois 61401 United States
  • Western Illinois Cancer Treatment Center
  • Galesburg Illinois 61401 United States
  • Northwestern Medicine Cancer Center Delnor
  • Geneva Illinois 60134 United States
  • Joliet Oncology-Hematology Associates Limited
  • Joliet Illinois 60435 United States
  • Illinois CancerCare-Kewanee Clinic
  • Kewanee Illinois 61443 United States
  • Northwestern Medicine Lake Forest Hospital
  • Lake Forest Illinois 60045 United States
  • Illinois CancerCare-Macomb
  • Macomb Illinois 61455 United States
  • Carle Physician Group-Mattoon/Charleston
  • Mattoon Illinois 61938 United States
  • Loyola University Medical Center
  • Maywood Illinois 60153 United States
  • Marjorie Weinberg Cancer Center at Loyola-Gottlieb
  • Melrose Park Illinois 60160 United States
  • Good Samaritan Regional Health Center
  • Mount Vernon Illinois 62864 United States
  • UC Comprehensive Cancer Center at Silver Cross
  • New Lenox Illinois 60451 United States
  • University of Chicago Medicine-Orland Park
  • Orland Park Illinois 60462 United States
  • Illinois CancerCare-Ottawa Clinic
  • Ottawa Illinois 61350 United States
  • Illinois CancerCare-Pekin
  • Pekin Illinois 61554 United States
  • Illinois CancerCare-Peoria
  • Peoria Illinois 61615 United States
  • Methodist Medical Center of Illinois
  • Peoria Illinois 61636 United States
  • Illinois CancerCare-Peru
  • Peru Illinois 61354 United States
  • Valley Radiation Oncology
  • Peru Illinois 61354 United States
  • Illinois CancerCare-Princeton
  • Princeton Illinois 61356 United States
  • Southern Illinois University School of Medicine
  • Springfield Illinois 62702 United States
  • Springfield Clinic
  • Springfield Illinois 62702 United States
  • Memorial Medical Center
  • Springfield Illinois 62781 United States
  • Cancer Care Specialists of Illinois-Swansea
  • Swansea Illinois 62226 United States
  • Southwest Illinois Health Services LLP
  • Swansea Illinois 62226 United States
  • Carle Cancer Center
  • Urbana Illinois 61801 United States
  • The Carle Foundation Hospital
  • Urbana Illinois 61801 United States
  • Northwestern Medicine Cancer Center Warrenville
  • Warrenville Illinois 60555 United States
  • Rush-Copley Healthcare Center
  • Yorkville Illinois 60560 United States
  • Reid Health
  • Richmond Indiana 47374 United States
  • Mary Greeley Medical Center
  • Ames Iowa 50010 United States
  • McFarland Clinic PC - Ames
  • Ames Iowa 50010 United States
  • McFarland Clinic PC-Boone
  • Boone Iowa 50036 United States
  • Medical Oncology and Hematology Associates-West Des Moines
  • Clive Iowa 50325 United States
  • Mercy Cancer Center-West Lakes
  • Clive Iowa 50325 United States
  • Alegent Health Mercy Hospital
  • Council Bluffs Iowa 51503 United States
  • Greater Regional Medical Center
  • Creston Iowa 50801 United States
  • Iowa Methodist Medical Center
  • Des Moines Iowa 50309 United States
  • Medical Oncology and Hematology Associates-Des Moines
  • Des Moines Iowa 50309 United States
  • Broadlawns Medical Center
  • Des Moines Iowa 50314 United States
  • Medical Oncology and Hematology Associates-Laurel
  • Des Moines Iowa 50314 United States
  • Mercy Medical Center - Des Moines
  • Des Moines Iowa 50314 United States
  • Iowa Lutheran Hospital
  • Des Moines Iowa 50316 United States
  • McFarland Clinic PC-Trinity Cancer Center
  • Fort Dodge Iowa 50501 United States
  • Trinity Regional Medical Center
  • Fort Dodge Iowa 50501 United States
  • McFarland Clinic PC-Jefferson
  • Jefferson Iowa 50129 United States
  • McFarland Clinic PC-Marshalltown
  • Marshalltown Iowa 50158 United States
  • Siouxland Regional Cancer Center
  • Sioux City Iowa 51101 United States
  • Methodist West Hospital
  • West Des Moines Iowa 50266-7700 United States
  • Mercy Medical Center-West Lakes
  • West Des Moines Iowa 50266 United States
  • University of Kansas Clinical Research Center
  • Fairway Kansas 66205 United States
  • Central Care Cancer Center - Garden City
  • Garden City Kansas 67846 United States
  • Central Care Cancer Center - Great Bend
  • Great Bend Kansas 67530 United States
  • Hays Medical Center
  • Hays Kansas 67601 United States
  • Kansas Institute of Medicine Cancer and Blood Center
  • Lenexa Kansas 66219 United States
  • Minimally Invasive Surgery Hospital
  • Lenexa Kansas 66219 United States
  • Olathe Medical Center
  • Olathe Kansas 66061 United States
  • Menorah Medical Center
  • Overland Park Kansas 66209 United States
  • Via Christi Hospital-Pittsburg
  • Pittsburg Kansas 66762 United States
  • Salina Regional Health Center
  • Salina Kansas 67401 United States
  • Saint Francis Hospital and Medical Center - Topeka
  • Topeka Kansas 66606 United States
  • University of Kansas Hospital-Westwood Cancer Center
  • Westwood Kansas 66205 United States
  • Cancer Center of Kansas-Wichita Medical Arts Tower
  • Wichita Kansas 67208 United States
  • Ascension Via Christi Hospitals Wichita
  • Wichita Kansas 67214 United States
  • Cancer Center of Kansas - Wichita
  • Wichita Kansas 67214 United States
  • Flaget Memorial Hospital
  • Bardstown Kentucky 40004 United States
  • Commonwealth Cancer Center-Corbin
  • Corbin Kentucky 40701 United States
  • Saint Joseph Radiation Oncology Resource Center
  • Lexington Kentucky 40504 United States
  • Saint Joseph Hospital East
  • Lexington Kentucky 40509 United States
  • Saint Joseph London
  • London Kentucky 40741 United States
  • Jewish Hospital
  • Louisville Kentucky 40202 United States
  • Saints Mary and Elizabeth Hospital
  • Louisville Kentucky 40215 United States
  • Jewish Hospital Medical Center Northeast
  • Louisville Kentucky 40245 United States
  • Jewish Hospital Medical Center South
  • Shepherdsville Kentucky 40165 United States
  • LSU Health Baton Rouge-North Clinic
  • Baton Rouge Louisiana 70805 United States
  • Louisiana Hematology Oncology Associates LLC
  • Baton Rouge Louisiana 70809 United States
  • Mary Bird Perkins Cancer Center
  • Baton Rouge Louisiana 70809 United States
  • Our Lady of the Lake Physicians Group - Medical Oncology
  • Baton Rouge Louisiana 70809 United States
  • Ochsner High Grove
  • Baton Rouge Louisiana 70836 United States
  • Northshore Oncology Associates-Covington
  • Covington Louisiana 70433 United States
  • Oncology Center of The South Incorporated
  • Houma Louisiana 70360 United States
  • Terrebonne General Medical Center
  • Houma Louisiana 70360 United States
  • East Jefferson General Hospital
  • Metairie Louisiana 70006 United States
  • LSU Healthcare Network / Metairie Multi-Specialty Clinic
  • Metairie Louisiana 70006 United States
  • Louisiana State University Health Science Center
  • New Orleans Louisiana 70112 United States
  • University Medical Center New Orleans
  • New Orleans Louisiana 70112 United States
  • Ochsner Medical Center Jefferson
  • New Orleans Louisiana 70121 United States
  • Lafayette Family Cancer Center-EMMC
  • Brewer Maine 04412 United States
  • Mercy Medical Center
  • Springfield Massachusetts 01104 United States
  • Hickman Cancer Center
  • Adrian Michigan 49221 United States
  • Saint Joseph Mercy Hospital
  • Ann Arbor Michigan 48106 United States
  • IHA Hematology Oncology Consultants-Brighton
  • Brighton Michigan 48114 United States
  • Saint Joseph Mercy Brighton
  • Brighton Michigan 48114 United States
  • Henry Ford Cancer Institute-Downriver
  • Brownstown Michigan 48183 United States
  • IHA Hematology Oncology Consultants-Canton
  • Canton Michigan 48188 United States
  • Saint Joseph Mercy Canton
  • Canton Michigan 48188 United States
  • Caro Cancer Center
  • Caro Michigan 48723 United States
  • IHA Hematology Oncology Consultants-Chelsea
  • Chelsea Michigan 48118 United States
  • Saint Joseph Mercy Chelsea
  • Chelsea Michigan 48118 United States
  • Hematology Oncology Consultants-Clarkston
  • Clarkston Michigan 48346 United States
  • Newland Medical Associates-Clarkston
  • Clarkston Michigan 48346 United States
  • Henry Ford Macomb Hospital-Clinton Township
  • Clinton Township Michigan 48038 United States
  • Henry Ford Medical Center-Fairlane
  • Dearborn Michigan 48126 United States
  • Henry Ford Hospital
  • Detroit Michigan 48202 United States
  • Ascension Saint John Hospital
  • Detroit Michigan 48236 United States
  • Great Lakes Cancer Management Specialists-Doctors Park
  • East China Township Michigan 48054 United States
  • Green Bay Oncology - Escanaba
  • Escanaba Michigan 49829 United States
  • Genesee Cancer and Blood Disease Treatment Center
  • Flint Michigan 48503 United States
  • Genesee Hematology Oncology PC
  • Flint Michigan 48503 United States
  • Genesys Hurley Cancer Institute
  • Flint Michigan 48503 United States
  • Hurley Medical Center
  • Flint Michigan 48503 United States
  • Academic Hematology Oncology Specialists
  • Grosse Pointe Woods Michigan 48236 United States
  • Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
  • Grosse Pointe Woods Michigan 48236 United States
  • Michigan Breast Specialists-Grosse Pointe Woods
  • Grosse Pointe Woods Michigan 48236 United States
  • Allegiance Health
  • Jackson Michigan 49201 United States
  • Sparrow Hospital
  • Lansing Michigan 48912 United States
  • Hope Cancer Clinic
  • Livonia Michigan 48154 United States
  • Saint Mary Mercy Hospital
  • Livonia Michigan 48154 United States
  • Great Lakes Cancer Management Specialists-Macomb Medical Campus
  • Macomb Michigan 48044 United States
  • Michigan Breast Specialists-Macomb Township
  • Macomb Michigan 48044 United States
  • Saint Mary's Oncology/Hematology Associates of Marlette
  • Marlette Michigan 48453 United States
  • Toledo Clinic Cancer Centers-Monroe
  • Monroe Michigan 48162 United States
  • Ascension Providence Hospitals - Novi
  • Novi Michigan 48374 United States
  • Henry Ford Medical Center-Columbus
  • Novi Michigan 48377 United States
  • 21st Century Oncology-Pontiac
  • Pontiac Michigan 48341 United States
  • Hope Cancer Center
  • Pontiac Michigan 48341 United States
  • Newland Medical Associates-Pontiac
  • Pontiac Michigan 48341 United States
  • Saint Joseph Mercy Oakland
  • Pontiac Michigan 48341 United States
  • Huron Medical Center PC
  • Port Huron Michigan 48060 United States
  • Lake Huron Medical Center
  • Port Huron Michigan 48060 United States
  • Great Lakes Cancer Management Specialists-Rochester Hills
  • Rochester Hills Michigan 48309 United States
  • Ascension Saint Mary's Hospital
  • Saginaw Michigan 48601 United States
  • Oncology Hematology Associates of Saginaw Valley PC
  • Saginaw Michigan 48604 United States
  • Henry Ford Macomb Health Center - Shelby Township
  • Shelby Michigan 48315 United States
  • Ascension Providence Hospitals - Southfield
  • Southfield Michigan 48075 United States
  • Bhadresh Nayak MD PC-Sterling Heights
  • Sterling Heights Michigan 48312 United States
  • Ascension Saint Joseph Hospital
  • Tawas City Michigan 48764 United States
  • Advanced Breast Care Center PLLC
  • Warren Michigan 48088 United States
  • Great Lakes Cancer Management Specialists-Macomb Professional Building
  • Warren Michigan 48093 United States
  • Macomb Hematology Oncology PC
  • Warren Michigan 48093 United States
  • Michigan Breast Specialists-Warren
  • Warren Michigan 48093 United States
  • Saint John Macomb-Oakland Hospital
  • Warren Michigan 48093 United States
  • Henry Ford West Bloomfield Hospital
  • West Bloomfield Michigan 48322 United States
  • Saint Mary's Oncology/Hematology Associates of West Branch
  • West Branch Michigan 48661 United States
  • Huron Gastroenterology PC
  • Ypsilanti Michigan 48106 United States
  • IHA Hematology Oncology Consultants-Ann Arbor
  • Ypsilanti Michigan 48197 United States
  • Riverwood Healthcare Center
  • Aitkin Minnesota 56431 United States
  • Sanford Joe Lueken Cancer Center
  • Bemidji Minnesota 56601 United States
  • Essentia Health Saint Joseph's Medical Center
  • Brainerd Minnesota 56401 United States
  • Fairview Ridges Hospital
  • Burnsville Minnesota 55337 United States
  • Cambridge Medical Center
  • Cambridge Minnesota 55008 United States
  • Mercy Hospital
  • Coon Rapids Minnesota 55433 United States
  • Essentia Health - Deer River Clinic
  • Deer River Minnesota 56636 United States
  • Essentia Health Saint Mary's - Detroit Lakes Clinic
  • Detroit Lakes Minnesota 56501 United States
  • Essentia Health Cancer Center
  • Duluth Minnesota 55805 United States
  • Essentia Health Saint Mary's Medical Center
  • Duluth Minnesota 55805 United States
  • Miller-Dwan Hospital
  • Duluth Minnesota 55805 United States
  • Fairview-Southdale Hospital
  • Edina Minnesota 55435 United States
  • Lake Region Healthcare Corporation-Cancer Care
  • Fergus Falls Minnesota 56537 United States
  • Essentia Health - Fosston
  • Fosston Minnesota 56542 United States
  • Unity Hospital
  • Fridley Minnesota 55432 United States
  • Essentia Health Hibbing Clinic
  • Hibbing Minnesota 55746 United States
  • Fairview Maple Grove Medical Center
  • Maple Grove Minnesota 55369 United States
  • Minnesota Oncology Hematology PA-Maplewood
  • Maplewood Minnesota 55109 United States
  • Saint John's Hospital - Healtheast
  • Maplewood Minnesota 55109 United States
  • Abbott-Northwestern Hospital
  • Minneapolis Minnesota 55407 United States
  • Hennepin County Medical Center
  • Minneapolis Minnesota 55415 United States
  • Minneapolis VA Medical Center
  • Minneapolis Minnesota 55417 United States
  • Health Partners Inc
  • Minneapolis Minnesota 55454 United States
  • Monticello Cancer Center
  • Monticello Minnesota 55362 United States
  • New Ulm Medical Center
  • New Ulm Minnesota 56073 United States
  • Essentia Health - Park Rapids
  • Park Rapids Minnesota 56470 United States
  • Fairview Northland Medical Center
  • Princeton Minnesota 55371 United States
  • North Memorial Medical Health Center
  • Robbinsdale Minnesota 55422 United States
  • Coborn Cancer Center at Saint Cloud Hospital
  • Saint Cloud Minnesota 56303 United States
  • Park Nicollet Clinic - Saint Louis Park
  • Saint Louis Park Minnesota 55416 United States
  • Regions Hospital
  • Saint Paul Minnesota 55101 United States
  • United Hospital
  • Saint Paul Minnesota 55102 United States
  • Essentia Health Sandstone
  • Sandstone Minnesota 55072 United States
  • Saint Francis Regional Medical Center
  • Shakopee Minnesota 55379 United States
  • Lakeview Hospital
  • Stillwater Minnesota 55082 United States
  • Sanford Thief River Falls Medical Center
  • Thief River Falls Minnesota 56701 United States
  • Essentia Health Virginia Clinic
  • Virginia Minnesota 55792 United States
  • Ridgeview Medical Center
  • Waconia Minnesota 55387 United States
  • Rice Memorial Hospital
  • Willmar Minnesota 56201 United States
  • Minnesota Oncology Hematology PA-Woodbury
  • Woodbury Minnesota 55125 United States
  • Sanford Cancer Center Worthington
  • Worthington Minnesota 56187 United States
  • Fairview Lakes Medical Center
  • Wyoming Minnesota 55092 United States
  • Gulfport Memorial Hospital
  • Gulfport Mississippi 39502 United States
  • University of Mississippi Medical Center
  • Jackson Mississippi 39216 United States
  • Saint Louis Cancer and Breast Institute-Ballwin
  • Ballwin Missouri 63011 United States
  • Central Care Cancer Center - Bolivar
  • Bolivar Missouri 65613 United States
  • Parkland Health Center-Bonne Terre
  • Bonne Terre Missouri 63628 United States
  • Cox Cancer Center Branson
  • Branson Missouri 65616 United States
  • Saint Francis Medical Center
  • Cape Girardeau Missouri 63703 United States
  • Southeast Cancer Center
  • Cape Girardeau Missouri 63703 United States
  • University of Missouri - Ellis Fischel
  • Columbia Missouri 65212 United States
  • Parkland Health Center - Farmington
  • Farmington Missouri 63640 United States
  • Centerpoint Medical Center LLC
  • Independence Missouri 64057 United States
  • Capital Region Southwest Campus
  • Jefferson City Missouri 65109 United States
  • Freeman Health System
  • Joplin Missouri 64804 United States
  • Mercy Hospital Joplin
  • Joplin Missouri 64804 United States
  • Truman Medical Center
  • Kansas City Missouri 64108 United States
  • Research Medical Center
  • Kansas City Missouri 64132 United States
  • Delbert Day Cancer Institute at PCRMC
  • Rolla Missouri 65401 United States
  • Mercy Clinic-Rolla-Cancer and Hematology
  • Rolla Missouri 65401 United States
  • Heartland Regional Medical Center
  • Saint Joseph Missouri 64507 United States
  • Saint Louis Cancer and Breast Institute-South City
  • Saint Louis Missouri 63109 United States
  • Mercy Hospital South
  • Saint Louis Missouri 63128 United States
  • Missouri Baptist Medical Center
  • Saint Louis Missouri 63131 United States
  • Mercy Hospital Saint Louis
  • Saint Louis Missouri 63141 United States
  • Sainte Genevieve County Memorial Hospital
  • Sainte Genevieve Missouri 63670 United States
  • Mercy Hospital Springfield
  • Springfield Missouri 65804 United States
  • CoxHealth South Hospital
  • Springfield Missouri 65807 United States
  • Missouri Baptist Sullivan Hospital
  • Sullivan Missouri 63080 United States
  • Missouri Baptist Outpatient Center-Sunset Hills
  • Sunset Hills Missouri 63127 United States
  • Mercy Hospital Washington
  • Washington Missouri 63090 United States
  • Community Hospital of Anaconda
  • Anaconda Montana 59711 United States
  • Billings Clinic Cancer Center
  • Billings Montana 59101 United States
  • Saint Vincent Healthcare
  • Billings Montana 59101 United States
  • Saint Vincent Frontier Cancer Center
  • Billings Montana 59102 United States
  • Bozeman Deaconess Hospital
  • Bozeman Montana 59715 United States
  • Saint James Community Hospital and Cancer Treatment Center
  • Butte Montana 59701 United States
  • Benefis Healthcare- Sletten Cancer Institute
  • Great Falls Montana 59405 United States
  • Great Falls Clinic
  • Great Falls Montana 59405 United States
  • Saint Peter's Community Hospital
  • Helena Montana 59601 United States
  • Kalispell Regional Medical Center
  • Kalispell Montana 59901 United States
  • Saint Patrick Hospital - Community Hospital
  • Missoula Montana 59802 United States
  • Community Medical Hospital
  • Missoula Montana 59804 United States
  • CHI Health Saint Francis
  • Grand Island Nebraska 68803 United States
  • CHI Health Good Samaritan
  • Kearney Nebraska 68847 United States
  • Saint Elizabeth Regional Medical Center
  • Lincoln Nebraska 68510 United States
  • Nebraska Methodist Hospital
  • Omaha Nebraska 68114 United States
  • Alegent Health Immanuel Medical Center
  • Omaha Nebraska 68122 United States
  • Alegent Health Bergan Mercy Medical Center
  • Omaha Nebraska 68124 United States
  • Alegent Health Lakeside Hospital
  • Omaha Nebraska 68130 United States
  • Creighton University Medical Center
  • Omaha Nebraska 68131 United States
  • Midlands Community Hospital
  • Papillion Nebraska 68046 United States
  • Carson Tahoe Regional Medical Center
  • Carson City Nevada 89703 United States
  • Cancer and Blood Specialists-Henderson
  • Henderson Nevada 89052 United States
  • Comprehensive Cancer Centers of Nevada - Henderson
  • Henderson Nevada 89052 United States
  • Comprehensive Cancer Centers of Nevada-Horizon Ridge
  • Henderson Nevada 89052 United States
  • Las Vegas Cancer Center-Henderson
  • Henderson Nevada 89052 United States
  • OptumCare Cancer Care at Seven Hills
  • Henderson Nevada 89052 United States
  • 21st Century Oncology-Henderson
  • Henderson Nevada 89074 United States
  • Comprehensive Cancer Centers of Nevada-Southeast Henderson
  • Henderson Nevada 89074 United States
  • Las Vegas Urology - Green Valley
  • Henderson Nevada 89074 United States
  • Las Vegas Urology - Pebble
  • Henderson Nevada 89074 United States
  • Urology Specialists of Nevada - Green Valley
  • Henderson Nevada 89074 United States
  • Las Vegas Urology - Pecos
  • Las Vegas Nevada 89074 United States
  • Desert West Surgery
  • Las Vegas Nevada 89102 United States
  • OptumCare Cancer Care at Oakey
  • Las Vegas Nevada 89102 United States
  • University Medical Center of Southern Nevada
  • Las Vegas Nevada 89102 United States
  • Hope Cancer Care of Nevada
  • Las Vegas Nevada 89103 United States
  • Cancer and Blood Specialists-Shadow
  • Las Vegas Nevada 89106 United States
  • Radiation Oncology Centers of Nevada Central
  • Las Vegas Nevada 89106 United States
  • Urology Specialists of Nevada - Central
  • Las Vegas Nevada 89106 United States
  • 21st Century Oncology
  • Las Vegas Nevada 89109 United States
  • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
  • Las Vegas Nevada 89109 United States
  • Sunrise Hospital and Medical Center
  • Las Vegas Nevada 89109 United States
  • HealthCare Partners Medical Group Oncology/Hematology-San Martin
  • Las Vegas Nevada 89113 United States
  • Las Vegas Prostate Cancer Center
  • Las Vegas Nevada 89113 United States
  • Las Vegas Urology - Sunset
  • Las Vegas Nevada 89113 United States
  • Radiation Oncology Centers of Nevada Southeast
  • Las Vegas Nevada 89119 United States
  • 21st Century Oncology-Vegas Tenaya
  • Las Vegas Nevada 89128 United States
  • Ann M Wierman MD LTD
  • Las Vegas Nevada 89128 United States
  • Cancer and Blood Specialists-Tenaya
  • Las Vegas Nevada 89128 United States
  • Comprehensive Cancer Centers of Nevada - Northwest
  • Las Vegas Nevada 89128 United States
  • HealthCare Partners Medical Group Oncology/Hematology-Tenaya
  • Las Vegas Nevada 89128 United States
  • Las Vegas Urology - Cathedral Rock
  • Las Vegas Nevada 89128 United States
  • Las Vegas Urology - Smoke Ranch
  • Las Vegas Nevada 89128 United States
  • OptumCare Cancer Care at MountainView
  • Las Vegas Nevada 89128 United States
  • Urology Specialists of Nevada - Northwest
  • Las Vegas Nevada 89128 United States
  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation
  • Las Vegas Nevada 89135 United States
  • Comprehensive Cancer Centers of Nevada - Town Center
  • Las Vegas Nevada 89144 United States
  • Comprehensive Cancer Centers of Nevada-Summerlin
  • Las Vegas Nevada 89144 United States
  • Summerlin Hospital Medical Center
  • Las Vegas Nevada 89144 United States
  • Las Vegas Cancer Center-Medical Center
  • Las Vegas Nevada 89148-2405 United States
  • 21st Century Oncology-Fort Apache
  • Las Vegas Nevada 89148 United States
  • Comprehensive Cancer Centers of Nevada
  • Las Vegas Nevada 89148 United States
  • OptumCare Cancer Care at Fort Apache
  • Las Vegas Nevada 89148 United States
  • Urology Specialists of Nevada - Southwest
  • Las Vegas Nevada 89148 United States
  • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
  • Las Vegas Nevada 89149 United States
  • Comprehensive Cancer Centers of Nevada - Central Valley
  • Las Vegas Nevada 89169 United States
  • University Cancer Center
  • Las Vegas Nevada 89169 United States
  • Hope Cancer Care of Nevada-Pahrump
  • Pahrump Nevada 89048 United States
  • Renown Regional Medical Center
  • Reno Nevada 89502 United States
  • Saint Mary's Regional Medical Center
  • Reno Nevada 89503 United States
  • Radiation Oncology Associates
  • Reno Nevada 89509 United States
  • New Hampshire Oncology Hematology PA-Concord
  • Concord New Hampshire 03301 United States
  • New Hampshire Oncology Hematology PA-Hooksett
  • Hooksett New Hampshire 03106 United States
  • AtlantiCare Health Park-Cape May Court House
  • Cape May Court House New Jersey 08210 United States
  • AtlantiCare Surgery Center
  • Egg Harbor Township New Jersey 08234 United States
  • Rutgers Cancer Institute of New Jersey
  • New Brunswick New Jersey 08903 United States
  • University of New Mexico Cancer Center
  • Albuquerque New Mexico 87102 United States
  • Hematology Oncology Associates of Central New York-Auburn
  • Auburn New York 13021 United States
  • Mary Imogene Bassett Hospital
  • Cooperstown New York 13326 United States
  • Hematology Oncology Associates of Central New York-East Syracuse
  • East Syracuse New York 13057 United States
  • Glens Falls Hospital
  • Glens Falls New York 12801 United States
  • Stony Brook University Medical Center
  • Stony Brook New York 11794 United States
  • Hematology Oncology Associates of Central New York-Onondaga Hill
  • Syracuse New York 13215 United States
  • AdventHealth Infusion Center Asheville
  • Asheville North Carolina 28803 United States
  • UNC Lineberger Comprehensive Cancer Center
  • Chapel Hill North Carolina 27599 United States
  • Southeastern Medical Oncology Center-Clinton
  • Clinton North Carolina 28328 United States
  • AdventHealth Infusion Center Haywood
  • Clyde North Carolina 28721 United States
  • Duke University Medical Center
  • Durham North Carolina 27710 United States
  • Southeastern Medical Oncology Center-Goldsboro
  • Goldsboro North Carolina 27534 United States
  • Margaret R Pardee Memorial Hospital
  • Hendersonville North Carolina 28791 United States
  • AdventHealth Hendersonville
  • Hendersonville North Carolina 28792 United States
  • Southeastern Medical Oncology Center-Jacksonville
  • Jacksonville North Carolina 28546 United States
  • Novant Health Oncology Specialists-Kernersville
  • Kernersville North Carolina 27284 United States
  • Novant Health Oncology Specialists-Mount Airy
  • Mount Airy North Carolina 27030 United States
  • Novant Health Oncology Specialists-Statesville
  • Statesville North Carolina 28625 United States
  • Novant Health Oncology Specialists-Davidson County
  • Thomasville North Carolina 27360 United States
  • Novant Health Oncology Specialists-Wilkesboro
  • Wilkesboro North Carolina 28659 United States
  • Novant Health Forsyth Medical Center
  • Winston-Salem North Carolina 27103 United States
  • Wake Forest University Health Sciences
  • Winston-Salem North Carolina 27157 United States
  • Sanford Bismarck Medical Center
  • Bismarck North Dakota 58501 United States
  • Essentia Health Cancer Center-South University Clinic
  • Fargo North Dakota 58103 United States
  • Sanford South University Medical Center
  • Fargo North Dakota 58103 United States
  • Southpointe-Sanford Medical Center Fargo
  • Fargo North Dakota 58103 United States
  • Sanford Medical Center Fargo
  • Fargo North Dakota 58104 United States
  • Sanford Broadway Medical Center
  • Fargo North Dakota 58122 United States
  • Sanford Roger Maris Cancer Center
  • Fargo North Dakota 58122 United States
  • Essentia Health - Jamestown Clinic
  • Jamestown North Dakota 58401 United States
  • Indu and Raj Soin Medical Center
  • Beavercreek Ohio 45431 United States
  • Strecker Cancer Center-Belpre
  • Belpre Ohio 45714 United States
  • Saint Elizabeth Boardman Hospital
  • Boardman Ohio 44512 United States
  • Dayton Physicians LLC-Miami Valley South
  • Centerville Ohio 45459 United States
  • Miami Valley Hospital South
  • Centerville Ohio 45459 United States
  • Adena Regional Medical Center
  • Chillicothe Ohio 45601 United States
  • University of Cincinnati/Barrett Cancer Center
  • Cincinnati Ohio 45219 United States
  • Good Samaritan Hospital - Cincinnati
  • Cincinnati Ohio 45220 United States
  • Oncology Hematology Care Inc-Kenwood
  • Cincinnati Ohio 45236 United States
  • Bethesda North Hospital
  • Cincinnati Ohio 45242 United States
  • TriHealth Cancer Institute-Westside
  • Cincinnati Ohio 45247 United States
  • TriHealth Cancer Institute-Anderson
  • Cincinnati Ohio 45255 United States
  • Mount Carmel East Hospital
  • Columbus Ohio 43213 United States
  • Columbus Oncology and Hematology Associates Inc
  • Columbus Ohio 43214 United States
  • Riverside Methodist Hospital
  • Columbus Ohio 43214 United States
  • Grant Medical Center
  • Columbus Ohio 43215 United States
  • The Mark H Zangmeister Center
  • Columbus Ohio 43219 United States
  • Mount Carmel Health Center West
  • Columbus Ohio 43222 United States
  • Doctors Hospital
  • Columbus Ohio 43228 United States
  • Good Samaritan Hospital - Dayton
  • Dayton Ohio 45406 United States
  • Miami Valley Hospital
  • Dayton Ohio 45409 United States
  • Dayton Physician LLC-Miami Valley Hospital North
  • Dayton Ohio 45415 United States
  • Miami Valley Hospital North
  • Dayton Ohio 45415 United States
  • Delaware Health Center-Grady Cancer Center
  • Delaware Ohio 43015 United States
  • Grady Memorial Hospital
  • Delaware Ohio 43015 United States
  • Dublin Methodist Hospital
  • Dublin Ohio 43016 United States
  • Armes Family Cancer Center
  • Findlay Ohio 45840 United States
  • Blanchard Valley Hospital
  • Findlay Ohio 45840 United States
  • Orion Cancer Care
  • Findlay Ohio 45840 United States
  • Atrium Medical Center-Middletown Regional Hospital
  • Franklin Ohio 45005-1066 United States
  • Dayton Physicians LLC-Atrium
  • Franklin Ohio 45005 United States
  • Central Ohio Breast and Endocrine Surgery
  • Gahanna Ohio 43230 United States
  • Dayton Physicians LLC-Wayne
  • Greenville Ohio 45331 United States
  • Wayne Hospital
  • Greenville Ohio 45331 United States
  • Mount Carmel Grove City Hospital
  • Grove City Ohio 43123 United States
  • Greater Dayton Cancer Center
  • Kettering Ohio 45409 United States
  • First Dayton Cancer Care
  • Kettering Ohio 45420 United States
  • Kettering Medical Center
  • Kettering Ohio 45429 United States
  • Fairfield Medical Center
  • Lancaster Ohio 43130 United States
  • OhioHealth Mansfield Hospital
  • Mansfield Ohio 44903 United States
  • Marietta Memorial Hospital
  • Marietta Ohio 45750 United States
  • OhioHealth Marion General Hospital
  • Marion Ohio 43302 United States
  • Knox Community Hospital
  • Mount Vernon Ohio 43050 United States
  • Licking Memorial Hospital
  • Newark Ohio 43055 United States
  • Newark Radiation Oncology
  • Newark Ohio 43055 United States
  • Mercy Health Perrysburg Cancer Center
  • Perrysburg Ohio 43551 United States
  • Southern Ohio Medical Center
  • Portsmouth Ohio 45662 United States
  • Springfield Regional Cancer Center
  • Springfield Ohio 45504 United States
  • Springfield Regional Medical Center
  • Springfield Ohio 45505 United States
  • Mercy Saint Anne Hospital
  • Toledo Ohio 43623 United States
  • Toledo Clinic Cancer Centers-Toledo
  • Toledo Ohio 43623 United States
  • Dayton Physicians LLC-Upper Valley
  • Troy Ohio 45373 United States
  • Upper Valley Medical Center
  • Troy Ohio 45373 United States
  • Saint Joseph Warren Hospital
  • Warren Ohio 44484 United States
  • Saint Ann's Hospital
  • Westerville Ohio 43081 United States
  • Saint Elizabeth Youngstown Hospital
  • Youngstown Ohio 44501 United States
  • Genesis Healthcare System Cancer Care Center
  • Zanesville Ohio 43701 United States
  • Cancer Centers of Southwest Oklahoma Research
  • Lawton Oklahoma 73505 United States
  • University of Oklahoma Health Sciences Center
  • Oklahoma City Oklahoma 73104 United States
  • Mercy Hospital Oklahoma City
  • Oklahoma City Oklahoma 73120 United States
  • Oklahoma Cancer Specialists and Research Institute-Tulsa
  • Tulsa Oklahoma 74146 United States
  • Saint Alphonsus Medical Center-Baker City
  • Baker City Oregon 97814 United States
  • Saint Charles Health System
  • Bend Oregon 97701 United States
  • Clackamas Radiation Oncology Center
  • Clackamas Oregon 97015 United States
  • Providence Cancer Institute Clackamas Clinic
  • Clackamas Oregon 97015 United States
  • Bay Area Hospital
  • Coos Bay Oregon 97420 United States
  • Legacy Mount Hood Medical Center
  • Gresham Oregon 97030 United States
  • Providence Newberg Medical Center
  • Newberg Oregon 97132 United States
  • Saint Alphonsus Medical Center-Ontario
  • Ontario Oregon 97914 United States
  • Legacy Good Samaritan Hospital and Medical Center
  • Portland Oregon 97210 United States
  • Providence Portland Medical Center
  • Portland Oregon 97213 United States
  • Providence Saint Vincent Medical Center
  • Portland Oregon 97225 United States
  • Oregon Health and Science University
  • Portland Oregon 97239 United States
  • Saint Charles Health System-Redmond
  • Redmond Oregon 97756 United States
  • Legacy Meridian Park Hospital
  • Tualatin Oregon 97062 United States
  • Lehigh Valley Hospital-Cedar Crest
  • Allentown Pennsylvania 18103 United States
  • Lehigh Valley Hospital - Muhlenberg
  • Bethlehem Pennsylvania 18017 United States
  • Bryn Mawr Hospital
  • Bryn Mawr Pennsylvania 19010 United States
  • Christiana Care Health System-Concord Health Center
  • Chadds Ford Pennsylvania 19317 United States
  • Main Line Health Center-Collegeville
  • Collegeville Pennsylvania 19426 United States
  • Geisinger Medical Center
  • Danville Pennsylvania 17822 United States
  • Pocono Medical Center
  • East Stroudsburg Pennsylvania 18301 United States
  • Main Line Health Center-Exton
  • Exton Pennsylvania 19341 United States
  • Geisinger Medical Center-Cancer Center Hazleton
  • Hazleton Pennsylvania 18201 United States
  • Lehigh Valley Hospital-Hazleton
  • Hazleton Pennsylvania 18201 United States
  • Geisinger Medical Oncology-Lewisburg
  • Lewisburg Pennsylvania 17837 United States
  • Lewistown Hospital
  • Lewistown Pennsylvania 17044 United States
  • Riddle Memorial Hospital
  • Media Pennsylvania 19063 United States
  • Bryn Mawr Health Center
  • Newtown Square Pennsylvania 19073 United States
  • Paoli Memorial Hospital
  • Paoli Pennsylvania 19301 United States
  • Geisinger Cancer Services-Pottsville
  • Pottsville Pennsylvania 17901 United States
  • Guthrie Medical Group PC-Robert Packer Hospital
  • Sayre Pennsylvania 18840 United States
  • Community Medical Center
  • Scranton Pennsylvania 18510 United States
  • Geisinger Medical Oncology-Selinsgrove
  • Selinsgrove Pennsylvania 17870 United States
  • Geisinger Medical Group
  • State College Pennsylvania 16801 United States
  • Geisinger Wyoming Valley/Henry Cancer Center
  • Wilkes-Barre Pennsylvania 18711 United States
  • Lankenau Medical Center
  • Wynnewood Pennsylvania 19096 United States
  • Prisma Health Cancer Institute - Easley
  • Easley South Carolina 29640 United States
  • Gibbs Cancer Center-Gaffney
  • Gaffney South Carolina 29341 United States
  • Saint Francis Hospital
  • Greenville South Carolina 29601 United States
  • Prisma Health Cancer Institute - Butternut
  • Greenville South Carolina 29605 United States
  • Prisma Health Cancer Institute - Faris
  • Greenville South Carolina 29605 United States
  • Prisma Health Greenville Memorial Hospital
  • Greenville South Carolina 29605 United States
  • Saint Francis Cancer Center
  • Greenville South Carolina 29607 United States
  • Prisma Health Cancer Institute - Eastside
  • Greenville South Carolina 29615 United States
  • Prisma Health Cancer Institute - Greer
  • Greer South Carolina 29650 United States
  • Gibbs Cancer Center-Pelham
  • Greer South Carolina 29651 United States
  • Prisma Health Cancer Institute - Seneca
  • Seneca South Carolina 29672 United States
  • Spartanburg Medical Center
  • Spartanburg South Carolina 29303 United States
  • Prisma Health Cancer Institute - Spartanburg
  • Spartanburg South Carolina 29307 United States
  • MGC Hematology Oncology-Union
  • Union South Carolina 29379 United States
  • Rapid City Regional Hospital
  • Rapid City South Dakota 57701 United States
  • Sanford Cancer Center Oncology Clinic
  • Sioux Falls South Dakota 57104 United States
  • Sanford USD Medical Center - Sioux Falls
  • Sioux Falls South Dakota 57117-5134 United States
  • Wellmont Bristol Regional Medical Center
  • Bristol Tennessee 37620 United States
  • Cookeville Regional Medical Center
  • Cookeville Tennessee 38501 United States
  • Regional Cancer Center at Indian Path Community Hospital
  • Kingsport Tennessee 37660 United States
  • Wellmont Holston Valley Hospital and Medical Center
  • Kingsport Tennessee 37660 United States
  • Saint Joseph Regional Cancer Center
  • Bryan Texas 77802 United States
  • American Fork Hospital / Huntsman Intermountain Cancer Center
  • American Fork Utah 84003 United States
  • Sandra L Maxwell Cancer Center
  • Cedar City Utah 84720 United States
  • Logan Regional Hospital
  • Logan Utah 84321 United States
  • Intermountain Medical Center
  • Murray Utah 84107 United States
  • McKay-Dee Hospital Center
  • Ogden Utah 84403 United States
  • Utah Valley Regional Medical Center
  • Provo Utah 84604 United States
  • Riverton Hospital
  • Riverton Utah 84065 United States
  • Dixie Medical Center Regional Cancer Center
  • Saint George Utah 84770 United States
  • Utah Cancer Specialists-Salt Lake City
  • Salt Lake City Utah 84106 United States
  • LDS Hospital
  • Salt Lake City Utah 84143 United States
  • University of Vermont Medical Center
  • Burlington Vermont 05401 United States
  • University of Vermont and State Agricultural College
  • Burlington Vermont 05405 United States
  • Wellmont Medical Associates-Bristol
  • Bristol Virginia 24201 United States
  • Bon Secours Memorial Regional Medical Center
  • Mechanicsville Virginia 23116 United States
  • Bon Secours Saint Francis Medical Center
  • Midlothian Virginia 23114 United States
  • Bon Secours DePaul Medical Center
  • Norfolk Virginia 23505 United States
  • Southwest VA Regional Cancer Center
  • Norton Virginia 24273 United States
  • Bon Secours Maryview Medical Center
  • Portsmouth Virginia 23707 United States
  • Bon Secours Saint Mary's Hospital
  • Richmond Virginia 23226 United States
  • Bon Secours Cancer Institute at Reynolds Crossing
  • Richmond Virginia 23230 United States
  • Bon Secours Health Center at Harbour View
  • Suffolk Virginia 23435 United States
  • Providence Regional Cancer System-Aberdeen
  • Aberdeen Washington 98520 United States
  • MultiCare Auburn Medical Center
  • Auburn Washington 98001 United States
  • Overlake Hospital Medical Center
  • Bellevue Washington 98004 United States
  • PeaceHealth Saint Joseph Medical Center
  • Bellingham Washington 98225 United States
  • Harrison HealthPartners Hematology and Oncology-Bremerton
  • Bremerton Washington 98310 United States
  • Harrison Medical Center
  • Bremerton Washington 98310 United States
  • Highline Medical Center-Main Campus
  • Burien Washington 98166 United States
  • Providence Regional Cancer System-Centralia
  • Centralia Washington 98531 United States
  • Swedish Cancer Institute-Edmonds
  • Edmonds Washington 98026 United States
  • Saint Elizabeth Hospital
  • Enumclaw Washington 98022 United States
  • Providence Regional Cancer Partnership
  • Everett Washington 98201 United States
  • Saint Francis Hospital
  • Federal Way Washington 98003 United States
  • MultiCare Gig Harbor Medical Park
  • Gig Harbor Washington 98335 United States
  • Swedish Cancer Institute-Issaquah
  • Issaquah Washington 98029 United States
  • Kadlec Clinic Hematology and Oncology
  • Kennewick Washington 99336 United States
  • Providence Regional Cancer System-Lacey
  • Lacey Washington 98503 United States
  • Saint Clare Hospital
  • Lakewood Washington 98499 United States
  • PeaceHealth Saint John Medical Center
  • Longview Washington 98632 United States
  • Jefferson Healthcare
  • Port Townsend Washington 98368 United States
  • Harrison HealthPartners Hematology and Oncology-Poulsbo
  • Poulsbo Washington 98370 United States
  • MultiCare Good Samaritan Hospital
  • Puyallup Washington 98372 United States
  • Valley Medical Center
  • Renton Washington 98055 United States
  • Pacific Gynecology Specialists
  • Seattle Washington 98104 United States
  • Swedish Medical Center-Ballard Campus
  • Seattle Washington 98107 United States
  • Swedish Medical Center-First Hill
  • Seattle Washington 98122-4307 United States
  • Swedish Medical Center-Cherry Hill
  • Seattle Washington 98122-5711 United States
  • PeaceHealth United General Medical Center
  • Sedro-Woolley Washington 98284 United States
  • Providence Regional Cancer System-Shelton
  • Shelton Washington 98584 United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - Valley
  • Spokane Valley Washington 99216 United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
  • Spokane Washington 99204 United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - North
  • Spokane Washington 99218 United States
  • Franciscan Research Center-Northwest Medical Plaza
  • Tacoma Washington 98405 United States
  • Mary Bridge Children's Hospital and Health Center
  • Tacoma Washington 98405 United States
  • MultiCare Tacoma General Hospital
  • Tacoma Washington 98405 United States
  • PeaceHealth Southwest Medical Center
  • Vancouver Washington 98664 United States
  • Legacy Salmon Creek Hospital
  • Vancouver Washington 98686 United States
  • Providence Saint Mary Regional Cancer Center
  • Walla Walla Washington 99362 United States
  • Providence Regional Cancer System-Yelm
  • Yelm Washington 98597 United States
  • West Virginia University Charleston Division
  • Charleston West Virginia 25304 United States
  • Duluth Clinic Ashland
  • Ashland Wisconsin 54806 United States
  • Northwest Wisconsin Cancer Center
  • Ashland Wisconsin 54806 United States
  • Marshfield Medical Center-EC Cancer Center
  • Eau Claire Wisconsin 54701 United States
  • Saint Vincent Hospital Cancer Center Green Bay
  • Green Bay Wisconsin 54301 United States
  • Saint Vincent Hospital Cancer Center at Saint Mary's
  • Green Bay Wisconsin 54303 United States
  • University of Wisconsin Hospital and Clinics
  • Madison Wisconsin 53792 United States
  • Holy Family Memorial Hospital
  • Manitowoc Wisconsin 54221 United States
  • Saint Vincent Hospital Cancer Center at Marinette
  • Marinette Wisconsin 54143 United States
  • Marshfield Medical Center-Marshfield
  • Marshfield Wisconsin 54449 United States
  • Community Memorial Hospital
  • Menomonee Falls Wisconsin 53051 United States
  • Medical College of Wisconsin
  • Milwaukee Wisconsin 53226 United States
  • Marshfield Clinic-Minocqua Center
  • Minocqua Wisconsin 54548 United States
  • ProHealth D N Greenwald Center
  • Mukwonago Wisconsin 53149 United States
  • Cancer Center of Western Wisconsin
  • New Richmond Wisconsin 54017 United States
  • ProHealth Oconomowoc Memorial Hospital
  • Oconomowoc Wisconsin 53066 United States
  • Saint Vincent Hospital Cancer Center at Oconto Falls
  • Oconto Falls Wisconsin 54154 United States
  • Marshfield Medical Center-Rice Lake
  • Rice Lake Wisconsin 54868 United States
  • HSHS Saint Nicholas Hospital
  • Sheboygan Wisconsin 53081 United States
  • Marshfield Clinic Stevens Point Center
  • Stevens Point Wisconsin 54482 United States
  • Saint Vincent Hospital Cancer Center at Sturgeon Bay
  • Sturgeon Bay Wisconsin 54235-1495 United States
  • ProHealth Waukesha Memorial Hospital
  • Waukesha Wisconsin 53188 United States
  • UW Cancer Center at ProHealth Care
  • Waukesha Wisconsin 53188 United States
  • The Alyce and Elmore Kraemer Cancer Care Center
  • West Bend Wisconsin 53095 United States
  • Marshfield Clinic - Weston Center
  • Weston Wisconsin 54476 United States
  • Cheyenne Regional Medical Center-West
  • Cheyenne Wyoming 82001 United States
  • Billings Clinic-Cody
  • Cody Wyoming 82414 United States
  • Welch Cancer Center
  • Sheridan Wyoming 82801 United States

View trial on ClinicalTrials.gov