Upper Tract Tumors

Does Xylinas' nomogram accurately predict intravesical recurrence risk after radical nephroureterectomy for primary upper urinary tract urothelial carcinoma when applied to Asian populations?

To validate a prognostic nomogram (Xylinas' nomogram) for intravesical recurrence after radical nephroureterectomy for primary upper urinary tract urothelial carcinoma patients of Asian descent.

Clinicopathological and survival data from 243 primary urinary tract urothelial carcinoma patients who underwent radical nephroureterectomy with bladder cuff excision between January 2004 and May 2017 were collated.

Management of the Distal Ureter in Radical Laparoscopic Nephroureterectomy for Upper Tract Urothelial Carcinoma.

Introduction: Management of the distal ureter during laparoscopic nephroureterectomy (LNU) for upper tract urothelial carcinoma (UTUC) is controversial.

Preintervention risk stratification of renal pelvic cancer and ureteral cancer should differ.

To identify different preintervention prognostic factors between renal pelvic cancer (RPc) and ureteral cancer (Uc) and to develop different preintervention risk stratifications for each cancer type.

Arsenic Exposure Is Associated with Significant Upper Tract Urothelial Carcinoma Health Care Needs and Elevated Mortality Rates - Beyond the Abstract

Arsenic exposure in Northern Chile: Antofagasta is located in the Atacama Desert, one of the aridest regions worldwide. Sources of water for consumption are scarce and originate from underground aquifers, leaching arsenic and other minerals as they flow downslope through the Andes Mountains. Until the 1950s, drinking water in the region met criteria considered acceptable for those times. However, in 1958, the waters of the Toconce river were captured using a 300 km piping system in order to satisfy the increasing demands of drinking water in this flourishing mining region. The latter caused an abrupt increase in mean arsenic concentrations in drinking water from around 90 to about 900 mg/L, exposing the population to levels up to 17 times higher than those recommended by the World Health Organization (WHO) at that time. Unfortunately, the need to support population and economic growth made the authorities to overlook potential risks related to arsenic exposure. Efforts to reduce arsenic started only over 10 years later. In 1970, a water treatment plant with adequate technology was installed, leading to significant drops in arsenic concentrations. Thereafter, a series of changes incorporating new cleaner sources up in the Andes and the modernization of the water supply network led to sustained reductions on arsenic levels, reaching WHO recommended levels by 1990.

Long-term ureteroscopic management of upper tract urothelial carcinoma: 28-year single-centre experience.

Long-term survival outcomes of patients who undergo endoscopic management of non-invasive upper tract urothelial carcinoma remain uncertain. The longest mean follow-up period in previous studies was 6.

Nephroureterectomy of Right-to-Left Crossed Fused Renal Ectopia with Urothelial Carcinoma.

Urothelial carcinoma in a crossed fused renal ectopia (CFRE) is an exceedingly rare clinical finding. We describe the surgical management used to treat upper tract urothelial carcinoma in a 64-year-old man with a right-to-left CFRE.

Diagnostic accuracy of ureteroscopic biopsy in predicting stage and grade at final pathology in upper tract urothelial carcinoma: Systematic review and meta-analysis.

To assess the accuracy of ureteroscopic (URS) biopsies in predicting stage and grade at final pathology in upper tract urothelial carcinoma (UTUC).

The meta-analysis was performed in accordance with the PRISMA statement.

Nomograms to predict overall and cancer-specific survival in patients with upper tract urothelial carcinoma: a large population-based study.

To develop and validate survival nomograms for predicting the overall survival (OS) and cancer-specific survival (CSS) in upper tract urothelial carcinoma (UTUC) patients.

Patients diagnosed with UTUC from 2010 to 2015 in the Surveillance, Epidemiology, and End Results (SEER) database were retrospectively enrolled.

Clinicopathological characteristics, prognosis, and chemosensitivity in patients with metastatic upper tract urothelial carcinoma.

To investigate the clinical characteristics, chemosensitivity, and outcome of metastatic upper tract urothelial carcinoma (UTUC).

Records of patients with metastatic UTUC since January 2005 were retrieved from a database that included clinical and survival data.

Intraoperative prophylactic intravesical chemotherapy to reduce bladder recurrence following radical nephroureterectomy.

Single, postoperative instillation of prophylactic intravesical chemotherapy (pIVC) is effective in reducing bladder cancer recurrences following radical nephroureterectomy (RNU). Despite high level evidence, pIVC is underutilized.