Androgen Deficiency
Adult Male Hypogonadism: A Review.
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Male hypogonadism is a clinical syndrome of signs and symptoms of testosterone deficiency and consistently low morning serum testosterone concentrations. The prevalence of hypogonadism due to hypothalamus, pituitary, or testes pathology is less than 1%, and the prevalence due to obesity (body mass index ≥30) is from 2% to 8%.
Worrying About Low Libido: A Mixed-Method Evaluation of Sexual Desire Across Gender, Sexual Orientation, and Relationship Status.
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Concerns about sexual desire are a frequent reason couples seek therapy. Consequently, researchers, clinicians, and educators have increasingly focused on understanding issues related to sexual desire.
Oncosexology: A Narrative Review on Sexual Health and Quality of Life in Cancer Patients.
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Cancer remains a major global public health problem. A key aspect of cancer care among survivors is sexual health. Cancer patients experience a range of sexual dysfunctions, including erectile dysfunction, vaginal dryness, dyspareunia, and reduced libido.
Congenital aromatase deficiency in an adult male: A case report of clinical course and symptom reversal with estrogen supplementation.
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Congenital aromatase deficiency is an autosomal recessive CYP19A1 loss-of-function disorder that blocks conversion of androgens to estrogens. A man with homozygous CYP19A1 c.628G > A (exon 5) presented with longstanding fatigue, low libido, and desire to maintain fertility.
A Single Centre Study to Describe the Changes in Serum Testosterone Concentration Following Application of Testosterone Gel in Post-Menopausal Women With Hypoactive Sexual Desire Disorder (HSSD) Already Receiving This as Part of Usual Care in Conjunction
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Hypoactive Sexual Desire Disorder (HSDD) is characterized by a long-term decrease in sexual desire (low-libido) causing personal distress. HSDD predominantly affects post-menopausal women or following oophorectomy.
The Mortality Gap Between Men and Women
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Functional testosterone deficiency in aging men: Clinical impact, diagnostic pathways, and treatment strategies.
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Testosterone constitutes an indispensable determinant of male corporeal integrity, psychological resilience, and overall vitality across the life course. Testosterone deficiency (male hypogonadism) represents an endocrine disorder capable of engendering a broad spectrum of somatic derangements and psychosocial sequelae.
What do older adults seeking sexual health information want to know about? Findings from the Australian SHAPE2 survey.
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Older adults are not traditionally a priority group for sexual health (SH) promotion, however recent years have seen increasing interest in this population. Effective SH promotion requires an understanding of older adults' interests, concerns and knowledge gaps.
"We Are Too Young to Worry": Late-Midlife Adults' Voices on Sexual Changes, Distress, and Help-Seeking Behaviors.
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Sexual health and well-being (SH&WB) in late midlife is an important yet underexplored aspect of healthy aging. Satisfying sexual activity contributes to psychological and relational well-being, yet midlife is marked by physiological changes, health issues, and social transitions that can affect sexual functioning.
Discovering a new paradigm: Gut microbiota as a central modulator of sexual health.
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The gut microbiota plays a pivotal role in human health, influencing diverse physiological processes, including those related to sexual health. Emerging evidence suggests a bidirectional relationship between the gut microbiota and sexual health, mediated by its impact on systemic inflammation, hormonal regulation, and immune function.