Urinary tract infection in patients with chronic kidney disease - Abstract

AIM: Chronic kidney disease (CKD) has become a burden of health care globally.

However, data on epidemiology, clinical features, and outcomes of urinary tract infection (UTI) in this population are scarce. This study aims to retrospectively review such data.

MATERIALS AND METHODS: A retrospective cohort study was conducted from 1 January 2005 to 31 December 2011 in patients with CKD requiring hospitalization. Patients who had upper and lower UTIs were compared for demography and clinical data. Logistic regressior was used to assess which variables were associated with upper UTI.

RESULTS: A total of 276 bacteriuria patients were admitted to our ward with upper and lower UTIs. The average ages of the upper and lower UTI patients were 59.21 +/- 16.54 and 71.18 +/- 14.77 years, respectively. The results of logistic regression analysis showed that age (OR 0.946, P < 0.001), female sex (OR 4.695, P < 0.001), and renal stones (OR 8.232, P < 0.001) were independently associated with upper UTI.

CONCLUSION: This study shows that patients with CKD and UTIs were elderly, and that females were prone to have more bacteriuria and upper UTIs than males. In addition, patients who had renal stones were more prone to have upper UTI than other bacteriuria patients Aggressive treatment of renal stones should be considered in these patients.

Written by:
Hsiao CY, Lin HL, Lin YK, Chen CW, Cheng YC, Lee WC, Wu TC.   Are you the author?
Department of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Taiwan.

Reference: Turk J Med Sci. 2014;44(1):145-9.

PubMed Abstract
PMID: 25558575

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