Community-acquired urinary tract infection in hospitalized children: Etiology and antimicrobial resistance. A comparison between first episode and recurrent infection - Abstract

Urinary tract infection (UTI) is common in infants and children, and Escherichia coli is the leading pathogen.

The aims of this study were to compare first episode of UTI with recurrent infection, reveal organisms that cause UTI, uropathogen resistance, and presence of bacteria producing extended-spectrum β-lactamase (ESBL). The first-UTI group included 456 children. E coli was the leading pathogen (80.5%), and Pseudomonas aeruginosa was found in 1.5%. The uropathogens were resistant to gentamicin (3.41%) and cefuroxime (5.71%), and highly resistant to cefamezin (37.39%). The recurrent-infection group included 106 children. E coli was also the leading pathogen, but 7.5% of the isolates were P aeruginosa (P = .002 compared with first-episode group); 6.6% were ESBL-producing bacteria compared with 1.1% in the first-episode group (P = .002). E coli is the leading pathogen in both groups. P aeruginosa and ESBL-producing bacteria were more common in the recurrent infection group.

Written by:
Sakran W, Smolkin V, Odetalla A, Halevy R, Koren A.   Are you the author?
Emek Medical Center, Afula, Israel; The Ruth and Baruch Rappaport School of Medicine, Technion, Haifa, Israel; Pediatric Nephrology Unit, Emek Medical Center, Afula, Israel; Emek Medical Center, Afula, Israel.  

Reference: Clin Pediatr (Phila). 2014 Nov 10. pii: 0009922814555974.
doi: 10.1177/0009922814555974

PubMed Abstract
PMID: 25385933 Infections Section