Asymptomatic bacteriuria (ASB) is a common finding in many populations, including healthy women and persons with underlying urologic abnormalities. The 2005 guideline from the Infectious Diseases Society of America recommended that ASB should be screened for and treated only in pregnant women or in an individual prior to undergoing invasive urologic procedures. Treatment was not recommended for healthy women; older women or men; or persons with diabetes, indwelling catheters, or spinal cord injury. The guideline did not address children and some adult populations, including patients with neutropenia, solid organ transplants, and nonurologic surgery. In the years since the publication of the guideline, further information relevant to ASB has become available. In addition, antimicrobial treatment of ASB has been recognized as an important contributor to inappropriate antimicrobial use, which promotes emergence of antimicrobial resistance. The current guideline updates the recommendations of the 2005 guideline, includes new recommendations for populations not previously addressed, and, where relevant, addresses the interpretation of nonlocalizing clinical symptoms in populations with a high prevalence of ASB.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2019 May 02 [Epub]
Lindsay E Nicolle, Kalpana Gupta, Suzanne F Bradley, Richard Colgan, Gregory P DeMuri, Dimitri Drekonja, Linda O Eckert, Suzanne E Geerlings, Béla Köves, Thomas M Hooton, Manisha Juthani-Mehta, Shandra L Knight, Sanjay Saint, Anthony J Schaeffer, Barbara Trautner, Bjorn Wullt, Reed Siemieniuk
Department of Internal Medicine, School of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada., Division of Infectious Diseases, Veterans Affairs Boston Healthcare System and Boston University School of Medicine, West Roxbury, Massachusetts., Division of Infectious Diseases, University of Michigan, Ann Arbor., Department of Family and Community Medicine, University of Maryland, Baltimore., Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison., Division of Infectious Diseases, University of Minnesota, Minneapolis., Department of Obstetrics and Gynecology and Department of Global Health, University of Washington, Seattle., Department of Internal Medicine, Amsterdam University Medical Center, The Netherlands., Department of Urology, South Pest Teaching Hospital, Budapest, Hungary., Division of Infectious Diseases, University of Miami, Florida., Division of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut., Library and Knowledge Services, National Jewish Health, Denver, Colorado., Department of Internal Medicine, Veterans Affairs Ann Arbor and University of Michigan, Ann Arbor., Department of Urology, Northwestern University, Chicago, Illinois., Section of Health Services Research, Department of Medicine, Baylor College of Medicine, Houston, Texas., Division of Microbiology, Immunology and Glycobiology, Lund University, Sweden., Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.