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- Andrea Alimonti discusses the challenges and advancements in the understanding and treatment of castration-resistant prostate cancer (CRPC). Dr. Alimonti highlights his team's efforts to comprehend the mechanisms of CRPC initiation and progression and explores potential therapies that could reverse or treat CRPC using anti-tumor immune responses. He emphasizes his team's contributions to the field...
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- Giorgio Brembilla presents an extensive overview of AI's integration and potential applications in radiology. He explains how AI and radiomics transform qualitative image evaluations into high-dimensional, mineable data, laying the foundation for AI-driven medical imaging. Detailing various AI techniques such as machine learning and deep learning, he emphasizes their potential to enhance imaging p...
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- Ashish Kamat provides a detailed description of the International Bladder Cancer Network (IBCN) and the International Bladder Cancer Group (IBCG). Despite their common focus on bladder cancer, he outlines their different missions and operational structures. The IBCN, established with a grant from the National Cancer Institute, aims to advance the diagnosis, prevention, and treatment of bladder can...
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- In this talk, Yohann Loriot discusses the work of the Groupe d'Etude des Tumeurs Uro-Génitales (GETUG), a French clinical research network focused on GU oncology. He explains GETUG's structure, a multidisciplinary group composed of medical oncologists, radiation oncologists, urologists, pathologists, statisticians, and radiologists. Loriot emphasizes the organization's commitment to conducting cli...
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- In his talk, Anders Bjartell highlights the key role of collaboration in advancing urological research and its importance for the European Association of Urology (EAU) Research Foundation. He outlines the Foundation's role in promoting and stimulating clinical and basic research through the establishment of registries and fostering a European network within urological research. Bjartell discusses...
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- Alberto Briganti presents significant advances in prostate cancer research over the last ten years. In summary, there has been a revolution in imaging for prostate cancer diagnosis and staging during the previous ten years. MRI use has increased significantly and is now recommended in guidelines as a triage test for patients with elevated PSA and suspected prostate cancer. PSMA PET scans have also...
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- Silke Gillessen provides a comprehensive presentation on Switzerland's oncological research group, SAKK, detailing its history, operations, challenges, and triumphs. Despite Switzerland's relatively small size and homogenous population, the group has made significant strides in conducting clinical trials, thanks in part to easy access to new drugs and robust funding from insurance companies. Dr. G...
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- Alessandro Larchel introduces a multidisciplinary program devoted to Von Hippel-Lindau (VHL) disease, a genetically defined renal cell carcinoma. VHL protein has a key role in renal cancer; if dysfunctional, it can promote cell proliferation and cancer. The program aids patients in three steps: indication for genetic referral, confirmation of diagnosis, and treatment or surveillance. This is essen...
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- Giorgio Gandaglia explores the ongoing clinical trials in the field of prostate cancer, from diagnosis to advanced stages of the disease. He begins by discussing the implementation of PET/CT and MRI in diagnosing prostate cancer and the potential benefits of these tools, including the reduction in clinically insignificant detections and biopsies. Gandaglia highlights the role of novel biomarkers i...
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- Daniele Raggi provides an extensive overview of ongoing clinical trials in bladder cancer. He starts by discussing the recent advancements in BCG-unresponsive disease, highlighting the evolution of treatments since the early 90s. He notes significant developments such as the FDA approval of pembrolizumab in 2020 and the consequent increase in research interest in this area. He then delves into the...
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