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Today's News | Monday, 20th May 2013 BERKELEY, CA (UroToday.com) -
Commentary on the USPTF Conclusions regarding Prostate Cancer Screening and Treatment: Evidence Based or Biased?
It is clear that many men treated for prostate cancer are not benefitted. It is also clear that “active surveillance” is a viable option for many men with ...
Loss of E-cadherin is one of the key steps in tumor progression.
OBJECTIVE: To compare the clinical outcomes of transumbilical multiport laparoscopic orchiopexy (TMLO) vs standard laparoscopic orchiopexy (SLO) for 1-stage management of impalpable testes in children.
PARK RIDGE, NJ USA (Press Release) - May 1, 2013 -
New Products Will Be Showcased at 2013 American Urological Association Annual Meeting
OBJECTIVE: To assess the morbidity, mortality, and impact on quality of life and renal function after laparoscopic cystectomy and ileal conduit in patients with multiple sclerosis with lower urinary tract symptom refractory to conservative management.
PURPOSE: The purpose of this study is to evaluate the preoperative factors that influenced postoperative sperm concentration after vasovasostomy.
OBJECTIVE: To, first, propose a novel scoring system to standardize reporting for percutaneous nephrolithotomy because the instruments currently available to predict the percutaneous nephrolithotomy outcomes are cumbersome, not validated, and of limited clinical utility; and, second, assess and ...
OBJECTIVE: To evaluate the efficacy and safety of long-acting i.m. testosterone undecanoate (TU) in Malaysian men with testosterone deficiency (TD).
Although millions of men have taken or are taking finasteride, there are no documented cases of successful pregnancy in the literature after discontinuation of the drug.
Peyronie's disease is a common debilitating condition for both men and their partners that results in penile deformity and compromises sexual functioning.
INTRODUCTION: This review explores the treatment of male chronic pelvic pain syndrome (CPPS) (i.e., chronic prostatitis) through the use of neuromodulation, which is the electrical stimulation of the nervous system.
OBJECTIVE: Analyze if bladder mucosa of patients with bladder pain syndrome (BPS) have more estrogen receptor (ER) and progesterone receptor (PR) than the normal population.
OBJECTIVE: To elucidate the effects of nocturia, one of the most bothersome of symptoms, on health-related quality of life (QOL), we examined the correlation between nocturia-specific QOL and other lower urinary tract symptoms (LUTS).
INTRODUCTION AND HYPOTHESIS: The transobturator suburethral sling is a common surgical treatment for stress urinary incontinence (SUI).
SAN DIEGO, CA USA (UroToday.com) - The focus of the meeting was “Utility of Urodynamics (UDS) in Clinical Practice,” with 10 minute presentations on multiple topics related to UDS.
BACKGROUND: Data describing urinary health in elderly, community-dwelling prostate cancer (PCa) survivors are limited.
BERKELEY, CA (UroToday.com) - In our recent article, we studied the differences between a group of patients with erectile dysfunction, compared to a control group.
A strong and independent association between lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) and erectile dysfunction (ED) has been widely evidenced in several clinical epidemiologic studies.
Background: Adrenocortical carcinoma (ACC) is a rare disease with a poor response to chemotherapy.
BACKGROUND: High levels of circulating C-reactive protein (CRP) have recently been linked to poor clinical outcome in various malignancies.
ALEXANDRIA, VA USA (PRESS RELEASE) -
Important Advances in Treatment for Aggressive Cancers, Surveillance Strategies and Cancer Prevention
We retrospectively evaluated 23 patients who had been administered pirarubicin by intravesical instillation once weekly for 5 weeks, after undergoing surgery for upper urinary tract cancer between May 2003 and October 2008.
SAN DIEGO, CA USA (UroToday.com) - These authors conducted a multi-institutional retrospective study to identify predictors of intravesical recurrence, and they also sought to develop a conditional-probability, competing-risk nomogram for prediction of intravesical recurrence after radical ...
BERKELEY, CA (UroToday.com) -
Drug Tolerability in the Choice of Second-Line Therapy for Metastatic Renal Cell Carcinoma
PURPOSE: The purpose of this study was to evaluate the applicability of the National Institute for Health and Clinical Excellence (NICE) guidelines for imaging studies in children under the age of three with first urinary tract infection (UTI).
Introduction: Renal pseudotumors simulate malignancy but they are, in fact, comprised of normal renal tissue.
BERKELEY, CA USA (Press Release) (PRWEB) - April 24, 2013 -
UroToday inaugurates their second of three comprehensive collaborations on the use of urinary catheters. The latest area, launching this week, is about intermittent catheterization (IC)
{slider AACN's National Teaching Institute & Critical Care Exposition20 May 2013 - 23 May 2013Boston, MA USA
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Join us in Boston for NTI 2013 — AACN’s National Teaching Institute & Critical Care Exposition and the Advanced Practice Institute — where you can ...
BERKELEY, CA USA (Press Release) - May 15, 2013 -
Xofigo approved three months ahead of schedule under priority review program
SAN DIEGO, CA USA (UroToday.com) - Presented by E. David Crawford, MD,1 Adam S. Kibel, MD,2 and Neal D.Shore, MD, FAC 3 at the American Urological Association (AUA) Annual Meeting - May 4 - 8, 2013 - San Diego Convention Center - San Diego, California USA
This position statement has been formulated by nurses from the United Kingdom Oncology Nursing Society (UKONS) to provide guidance on the provision of nurse-led chemotherapy review clinics for adult patients.
"Beyond the Abstract," Genitourinary malignancy presenting as an ocular metastasis: A case report and review of the literature, by Shilo Lefresne, MD and Alysa Fairchild MD, FRCPC
BERKELEY, CA (UroToday.com) - A small proportion (2-5%) of patients with cancer will develop metastases to the ocular or orbital region. Prostate cancer is the third most common primary site for these metastases, behind only breast and lung cancer.[1]
AUA 2013 - Session Highlights: The impact of seminal vesicle invasion in patients with positive lymph node involvement at the time of radical prostatectomy
SAN DIEGO, CA USA (UroToday.com) - Seminal vesicle invasion (SVI) and positive lymph node involvement (LNI) are well-described adverse pathologic features that portend poor outcomes following radical prostatectomy (RP).
Expression of lysophosphatidic acid receptor 1 and relation with cell proliferation, apoptosis, and angiogenesis on preneoplastic changes induced by cadmium chloride in the rat ventral prostate - ...
BACKGROUND: Lysophosphatidic acid (LPA) is a phospholipid growth factor involved in cell proliferation, differentiation, migration, inflammation, angiogenesis, wound healing, cancer invasion, and survival.
Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-γ mice - Abstract
Reconstitution of tumor development in immunodeficient mice from disaggregated primary human tumor cells is always challenging.
Computed tomography findings in patients with pediatric blunt renal trauma in whom expectant (nonoperative) management failed - Abstract
OBJECTIVE: To determine whether the features on a computed tomography (CT) scan can predict the need for urologic intervention in a pediatric blunt renal trauma population initially treated with expectant management.
Assisted reproductive techniques and risk of exstrophy-epispadias complex: A German case-control study - Abstract
PURPOSE: We assessed the risk of exstrophy-epispadias complex in children conceived by in vitro fertilization or intracytoplasmic sperm injection.
A +20% adjustment in the CT measured ureteral length is an accurate predictor of true ureteral length prior to ureteral stent placement - Abstract
Purpose: Correct length of ureteral stent is important in minimizing post-placement discomfort and stent migration.
Outcomes of distal ureteral reconstruction through reimplantation with psoas hitch, Boari flap, or ureteroneocystostomy for benign or malignant ureteral obstruction or injury - Abstract
OBJECTIVE: To assess functional outcomes and complications of ureteroneocystotomies (UNCs) with or without psoas hitch or Boari flap in the reconstruction and repair of the ureter.
Downstream complications following urinary diversion - Abstract
INTRODUCTION: Surveillance following urinary diversion should be tailored to capture complications downstream from the initial reconstruction.
Postoperative outcomes after continent versus incontinent urinary diversion at the time of pelvic exenteration for gynecologic malignancies - Abstract
OBJECTIVE: To compare outcomes of patients undergoing continent or incontinent urinary diversion after pelvic exenteration for gynecologic malignancies.
Advances in surgical treatment of male infertility - Abstract
A male factor is the only cause of infertility in 30% to 40% of couples.
Vasectomy demographics and postvasectomy desire for future children: Results from a contemporary national survey - Abstract
OBJECTIVE: To describe the longitudinal demographics and family planning attitudes of vasectomized men with the use of the National Survey for Family Growth (NSFG).
Percutaneous nephrostomy, nephrolithotomy and combined ureteroscopic lithotripsy using the supine approach - Abstract
OBJECTIVES: (1) To evaluate the safety and efficacy of supine percutaneous nephrostomy, nephrolithotomy, and combined percutaneous nephrolithotomy and ureteroscopic lithotripsy.
The feasibility of regional anesthesia in the percutaneous nephrolithotomy with supracostal approach and its comparison with general anesthesia - Abstract
There are various approaches for the percutaneous nephrolithotomy (PCNL).
Prevalence of andropausal symptoms among Kuwaiti males - Abstract
Andropause is a syndrome that usually occurs during men's midlife.
Negative association between testosterone concentration and inflammatory markers in young men: A nested cross-sectional study - Abstract
OBJECTIVE: Low grade systemic inflammation (LGSI) as well as androgen deficiency has in older men been associated with several pathologies, including cardiovascular disease (CVD).
Study of sperm protein profile in men with and without varicocele using two-dimensional gel electrophoresis - Abstract
OBJECTIVE: To compare the sperm protein profile between men with and without varicocele.
Overview of current approaches to the evaluation and management of male infertility - Abstract
Infertility, the inability to conceive after one year of regular, unprotected intercourse, is secondary to male-only factors in 20% and a combination of male and female factors in 30% to 40% of cases.
AUA 2013 - Podcast: Intralesional therapy with collagenase clostridium histolyticum (CCH), a promising, non-surgical, minimally-invasive option for the treatment of Peyronie's disease
SAN DIEGO, CA USA (UroToday.com) - In this podcast, Dr. Wayne J. G. Hellstrom from Tulane University School of Medicine in New Orleans gives a summary of some of the key points and discusses results from the Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies (IMPRESS) I ...
Evidence supports efficacy of enzyme in treatment of Peyronie's disease
SAN DIEGO, CA USA (Press Release) - May 6, 2013 - According to data from the Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies (IMPRESS) I and II phase three trials, men who received injectable treatments of collagenase clostridium histolyticum (CCH), an enzyme that breaks ...
Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: A prospective cohort study - Abstract
OBJECTIVE: To investigate the role periurethral fibrosis secondary to chronic prostatic inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms (LUTS) in male patients.
Semen quality and associated reproductive indicators in middle-aged males: The role of non-malignant prostate conditions and genital tract inflammation - Abstract
PURPOSE: To compare the associations between non-malignant prostate conditions, genital tract inflammation, and reproductive function in middle-aged men.
Improvement by the phytotherapeutic agent Eviprostat® of detrusor overactivity, down-regulation of pharmacological receptors and urinary cytokines in rats with cyclophosphamide-induced cystitis, ...
BERKELEY, CA (UroToday.com) - Interstitial cystitis (IC) is a chronic, abacterial, inflammatory disease of the bladder characterized by urinary frequency, urgency, and suprapubic pain associated with bladder filling and relieved by voiding.
Quality of information on the internet related to bladder pain syndrome: A systematic review of the evidence - Abstract
INTRODUCTION AND HYPOTHESIS: Bladder pain syndrome (BPS) has an impact on quality of life and available treatments often only provide temporary symptomatic relief.
Survey on lower urinary tract symptoms and sleep disorders in patients treated at urology departments - Abstract
OBJECTIVES: This study examined the association between sleep disorders and lower urinary tract symptoms in patients who had visited urology departments.
Survey on the perception of urogenital complications in diabetic patients - Abstract
PURPOSE: Retinopathy, neuropathy, and nephropathy are well-known complications of diabetes; they are often expected to occur and, therefore, are usually tested for.
Post-reduction stress urinary incontinence rates in posterior versus anterior pelvic organ prolapse: A secondary analysis - Abstract
INTRODUCTION/HYPOTHESIS: Stress incontinence with vaginal prolapse reduction is less common in women with posterior-predominant prolapse (rectocele) compared with those with anterior-predominant prolapse (cystocele).
Randomized controlled trial of pelvic floor muscle training with or without biofeedback for urinary incontinence - Abstract
INTRODUCTION AND HYPOTHESIS: To compare the effects of pelvic floor muscle training (PFMT), with or without biofeedback (BF), for stress urinary incontinence (SUI), focusing on condition-specific quality of life (QOL) outcomes.
Urethral dilatation: Is there any benefit over cystoscopy and distension? A randomized trial in women with overactive bladder symptoms - Abstract
AIM: To evaluate the effect of urethral dilatation (UD) on urgency symptoms in women with overactive bladder (OAB) and voiding dysfunction.
Botulinum toxin treatment for bladder dysfunction - Abstract
Botulinum toxin A is available under three different protein complexes that are not interchangeable until appropriate comparative studies are undertaken.
Psychometric properties and practicability of the self-report urinary incontinence questionnaire in patients with pelvic-floor dysfunction seeking outpatient rehabilitation - Abstract
BACKGROUND: Pelvic floor dysfunction (PFD) affects a substantial proportion of individuals, mostly women.
Skill acquisition, credentialing, and maintenance of skills in surgical treatment of pelvic organ prolapse and urinary incontinence - Abstract
Female pelvic medicine and reconstructive surgery, or urogynecology, has undergone a unique evolution with recent recognition as a subspecialty of Obstetrics and Gynecology and Urology.
A systematic review assessing the economic impact of sildenafil citrate (Viagra(®) ) in the treatment of erectile dysfunction - Abstract
INTRODUCTION: Sildenafil was the first oral phosphodiesterase type 5 (PDE5) inhibitor introduced as primary therapy for erectile dysfunction (ED).
Adjunctive treatment with lodenafil carbonate for erectile dysfunction in outpatients with schizophrenia and spectrum: A randomized, double-blind, crossover, placebo-controlled trial - Abstract
INTRODUCTION: Evidence is accumulating to support the presence of erectile dysfunction in patients with schizophrenia.
Prostatic artery embolization in the treatment of benign prostatic hyperplasia: Short and medium follow-up - Abstract
To evaluate the short and mid-term results of prostatic artery embolization in patients with benign prostatic embolization.
Prostatic arterial embolization: Post-procedural follow-up - Abstract
Prostatic arterial embolization (PAE) gained special attention in the past years as a potential minimally invasive technique for benign prostatic hyperplasia.
Surgery for adrenocortical carcinoma in the Netherlands: Analysis of national cancer registry data - Abstract
OBJECTIVE: Adrenocortical carcinoma (ACC) is a rare disease with an estimated incidence of 1-2 cases per 1 million inhabitants.
AUA 2013 - Session Highlights: The metastatic potential of retroperitoneal tumors: Analysis and comparison of renal cell carcinoma (RCC), adrenocortical carcinoma (ACC), and retroperitoneal sarcoma ...
SAN DIEGO, CA USA (UroToday.com) - There is a paucity of literature that compares various retroperitoneal tumors and their behavior.
Penile cancer: Diagnosis, clinical features and management - Abstract
This article aims to provide the reader with an overview of penile cancer.
AUA 2013 - Session Highlights: Prognostic factors and outcomes after definitive treatment for primary urethral cancer: Results from the international collaboration on primary urethral carcinoma
SAN DIEGO, CA USA (UroToday.com) - The aim of this multi-institutional (9 tertiary academic centers) study was to evaluate risk factors for survival in a large international cohort of patients with primary urethral cancer.
Testicular tumor arising in intra-abdominal testis which was not detected at prior orchidopexy : A case report - Abstract
A 35-year-old man with an intra-abdominal testicular tumor arising from the right unresolved intraabdominal testis is reported.
Laparoscopic lumbar-aortic lymphadenectomy in residual post-chemotherapy tumours in testicular cancer - Abstract
INTRODUCTION: Open lumbar-aortic lymphadenectomy (OLAL) is the gold standard for treating post-chemotherapy retroperitoneal masses.
A population-based study of tumours of the renal pelvis and ureter: Incidence, aetiology and histopathological findings - Abstract
Objective: Carcinoma of the renal pelvis and ureter are unusual tumours and our limited knowledge comes mainly from case reports and small series from large academic hospitals, as a rule without histopathological review.
The treatment of recurrent urothelial tumors of the upper urinary system and at urostomy site following radical cystectomy with intraureteral Bacillus Calmette-Guérin and cryotherapy - Abstract
Urinary bladder carcinoma is the second most common cancer of the urinary system.
AUA 2013 - Session Highlights: Access to care predicts adequate pelvic lymph node dissection in patients undergoing radical cystectomy for muscle-invasive bladder cancer
SAN DIEGO, CA USA (UroToday.com) - Authors from Vanderbilt University analyzed patients with clinical T2 or T3 bladder cancer, from the National Cancer Data Base (NCDB) cancer registry and diagnosed between 1998 and 2010, to identify the likelihood of these patients receiving an adequate pelvic ...
AUA 2013 - Session Highlights: Comparative performance of comorbidity indices for estimating perioperative and 5-year all-cause mortality following radical cystectomy
SAN DIEGO, CA USA (UroToday.com) - Dr. Stephen Boorjian and colleagues from Mayo Clinic investigated the comparative ability of various comorbidity indices to predict perioperative and 5-year all-cause mortality (ACM) following radical cystectomy.
Diagnostic radiation exposure during surveillance in patients with pT1a renal cell carcinoma - Abstract
OBJECTIVE: To determine the pattern of postoperative radiographic surveillance in patients with pT1a renal cell carcinoma (RCC) at a tertiary care hospital.
Metachronous occurrence of triple malignancies of kidneys, prostate, and breast. A case report and review of the literature - Abstract
Multiple consecutive cancers involving different organs in a male individual are presented.
Pediatric urinary tract infection: Does the evidence support aggressively pursuing the diagnosis? - Abstract
The epidemiology of pediatric fever has changed considerably during the past 2 decades with the development of vaccines against the most common bacterial pathogens causing bacteremia and meningitis.
Challenges in assessing nursing home residents with advanced dementia for suspected urinary tract infections - Abstract
OBJECTIVES: To describe the presentation of suspected urinary tract infections (UTIs) in nursing home (NH) residents with advanced dementia and how they align with minimum criteria to justify antimicrobial initiation.
Comparison of symptom management strategies for pain, erectile dysfunction, and depression in patients receiving chronic hemodialysis: A cluster randomized effectiveness trial - Abstract
BACKGROUND AND OBJECTIVES: Pain, erectile dysfunction (ED), and depression are common yet frequently untreated in chronic hemodialysis patients.
Contrast-enhanced ultrasound assessment of complex cystic lesions in renal transplant recipients with acquired cystic kidney disease: Preliminary experience - Abstract
We prospectively studied the potential value of contrast-enhanced ultrasound (CEUS) to characterize complex acquired cystic kidney disease (ACKD) or suspected solid renal masses, avoiding the risk of inducing acute kidney injury in 138 renal transplant recipients by contrast-enhanced computed ...
Annapolis/Glen Burnie Maryland urology group of ten is recruiting additional urologists with fellowship training in pediatric urology and female urology/urodynamics
ANNAPOLIS, MD USA - April 19, 2013 - Well-established, physician-owned urology practice is recruiting urologists with fellowship training in pediatric urology and female urology/urodynamics.
Challenges facing academic urology training programs: An impending crisis - Abstract
Objective: To determine the most pressing issues facing academic urology training centers. The supply of urologists per capita in the United States continues to decrease. Stricter resident requirements, restriction of resident duty hours, and a Graduate Medical Education (GME) funding cap on ...
Conferences
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Conferences Page - Content Coming Soon!
History of Indwelling Catheters - Bard
For 106 years C. R. Bard, Inc. has maintained its dedication to creating innovative products and services for health-care providers and patients worldwide. Through its strong traditions of quality, integrity, service and innovation, Bard serves as a leading developer, manufacturer and ...
A dose-ranging study of cabozantinib in men with castration-resistant prostate cancer and bone metastases - Abstract
Background: Cabozantinib is an oral MET/VEGFR2 inhibitor.
Management of castrate resistant prostate cancer-recent advances and optimal sequence of treatments - Abstract
Until 2010, chemotherapy with docetaxel was the only approved agent for treatment of metastatic castrate resistant prostate cancer (mCRPC).
AUA 2013 - Poster: Treatment practice patterns in metastatic castration-resistant prostate cancer (mCRPC) patients prior to receiving sipuleucel-T: Data from PROCEED
SAN DIEGO, CA USA (UroToday.com) - Presented by Matthew R. Cooperberg, MD,1 Oliver Sartor, MD,2 Christopher Pieczonka, MD,3 Raoul S. Concepcion, MD, FACS,4 Vahan Kassabian, MD,5 Ronald Tutrone, MD, FACS, CPI,6 James Bailen, MD,7 Neal Shore, MD, FACS,8 Lawrence Karsh, MD, FACS,9 Bernard Hertzman, MD, ...
AUA 2013 - Poster: Safety and changes in laboratory parameters associated with sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC): Phase 2 ProACT study
SAN DIEGO, CA USA (UroToday.com) - Presented by Thomas Gardner,1 Daniel Petrylak,2 John Corman,3 Simon Hail,4 Ralph Weinstein,5 Robert Sims,6 Todd DeVries,6 and Celestia Higano7 at the American Urological Association (AUA) Annual Meeting - May 4 - 8, 2013 - San Diego Convention Center - San Diego, ...
Evaluation of a nurse-led service for follow up of patients with prostate cancer - Abstract
The incidence of prostate cancer in Scotland continues to grow; men are now living with their disease which can be seen as an increased burden for the health service and in particular the Uro-Oncology team which delivers its treatment and manage its follow up.
Bone micro-environment in prostate cancer: impact, treatment and implications for nursing practice - Abstract
Prostate cancer is a substantial worldwide health care challenge. The disease is associated with detrimental effects on bone remodelling, mediated by the RANK/RANK ligand (RANKL) system.
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