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Categories Erectile Dysfunction

Newly diagnosed erectile dysfunction and risk of depression: A population-based 5-year follow-up study in Taiwan - Abstract

INTRODUCTION: Depression might increase the risk of erectile dysfunction (ED), and ED might further exacerbate depression.

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Effect of levitra on sustenance of erection (EROS): - Abstract

Complete Title: Effect of levitra on sustenance of erection (EROS): An open-label, prospective, multicenter, single-arm study to investigate erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction

Context To investigate the change of erection duration measured by stopwatch with flexible dose vardenafil administered for 8 weeks in subjects with erectile dysfunction (ED). Effect of levitra on sustenance of erection was an open-label, prospective, multicenter and single-arm study designed to measure the duration of erection in men with ED receiving a flexible dose of vardenafil over an 8-week treatment period. Patients were instructed to take vardenafil 10 mg 60 min before attempting the intercourse. Vardenfil could be increased to 20 mg or decreased to 5 mg concerning patients' efficacy and safety. Following the initial screening, patients entered a 4-week treatment-free run-in phase and 8-week treatment period, during which they were instructed to attempt intercourse at least four times on four separate days. A total of 95 men were enrolled in 10 centers. After the 8 weeks treatment, the mean duration of erection leading to successful intercourse was statistically superior when patients were treated with vardenafil. After an 8-week treatment, the duration of erection leading to successful intercourse was 9.39 min. There were significant benefits with vardenafil in all domains of International Index of Erectile Function. Secondary efficacy end points included success rate of penetration, maintaining erection, ejaculation and satisfaction were superior when patients were treated with vardenafil. There was a significant correlation between duration of erection with other sexual factors. Also partner's sexual satisfaction was increased with vardenafil. Most adverse events were mild or moderate in severity. Vardenafil was safe and well tolerated. Vardenafil therapy provided a statistically superior duration of erection leading to successful intercourse in men with ED with female partner.

Written by:
Shin YS, Lee SW, Park K, Chung WS, Kim SW, Hyun JS, Moon DG, Yang SK, Ryu JK, Yang DY, Moon KH, Min KS, Park JK.   Are you the author?
Department of Urology, Chonbuk National University Medical School and Institute for Medical Sciences, Chonbuk National University and Biomedical Research Institute and Clinical Trial Center of Medical Device of Chonbuk National University Hospital, Jeonju, South Korea; Department of Urology, Sungkyunkwan University School of Medicine, Seoul, Korea; Department of Urology, Chonnam National University Medical School, Gwangju, Korea; Department of Urology, Ewha Womans University School of Medicine, Seoul, Korea; Department of Urology, The Catholic University of Korea College of Medicine, Seoul, Korea; Department of Urology, Gyeongsang National University School of Medicine, Jinju, Korea; Department of Urology, Korea University College of Medicine, Seoul, Korea; Department of Urology, Konkuk University School of Medicine, Chungju, Korea; Department of Urology, Inha University School of Medicine, Incheon, Korea; Department of Urology, Hallym University College of Medicine, Chuncheon, Korea; Department of Urology, Yeungnam University College of Medicine, Daegu, Korea; Department of Urology, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Reference: Int J Impot Res. 2014 Dec 4. Epub ahead of print.
doi: 10.1038/ijir.2014.39


PubMed Abstract
PMID: 25471318

UroToday.com Erectile Dysfunction Section

Initial experience with linear focused shockwave treatment for erectile dysfunction: A 6-month follow-up pilot study - Abstract

Low-intensity shockwaves (LISW) are known to produce revascularization and have been in evaluation and in use to treat erectile dysfunction (ED).

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Can low-intensity extracorporeal shockwave therapy improve erectile dysfunction? A prospective, randomized, double-blind, placebo-controlled study - Abstract

Objective: The aim of this study was to investigate whether low-intensity extracorporeal shockwave therapy (LI-ESWT) can be used as a treatment for men with erectile dysfunction of organic origin.

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Does the etiology affect the outcome and satisfaction rates of penile prosthesis implantation surgery? - Abstract

Our aim was to compare the outcomes and satisfaction rates of men undergoing penile prostheses implantation (PPI) secondary to radical prostatectomy (RP) and other causes of vasculogenic erectile dysfunction (ED).

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Tubing erosion of an inflatable penile prosthesis long after implantation - Abstract

INTRODUCTION: Erosion through skin of connecting tubing of an inflatable penile prosthesis (IPP) has not been previously reported.

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National practice patterns for treatment of erectile dysfunction with penile prosthesis implantation - Abstract

PURPOSE: The increase in medical treatment options for the management of erectile dysfunction (ED) has changed how urologists approach ED.

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The discovery of avanafil for the treatment of erectile dysfunction: A novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor - Abstract

Novel pyrimidine-5-carboxamide derivatives bearing a 3-chloro-4-methoxybenzylamino group at the 4-position were identified as potent and highly selective phosphodiesterase 5 inhibitors.

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Switching from nitrate therapy to ranolazine in patients with coronary artery disease receiving phosphodiesterase type-5 inhibitors for erectile dysfunction - Abstract

Coronary artery disease (CAD) and erectile dysfunction (ED) frequently coexist.

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Male sexual dysfunction and ankylosing spondylitis: A systematic review and meta-analysis - Abstract

OBJECTIVE: No consensus has been reached on sexual dysfunction in men with ankylosing spondylitis (AS).

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