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Today's News | Friday, 24th May 2013 CHAPEL HILL, NC USA (Press Release) - May 20, 2013 -
Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from UNC suggests that the therapy may not be more effective than older, less expensive forms of radiation therapy in ...
To assess the efficacy of meloxicam, a non-steroidal anti-inflammatory drug (NSAID), on three human urinary bladder-cancer cell lines (HT1376, T24 and 5637) and on mice urinary bladder cancer chemically induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN).
BACKGROUND: Complete duplication of the bladder and urethra is a rare congenital anomaly and usually occurs in association with other organ anomalies.
Purpose: To describe our initial experience with robot-assisted ureteroureterostomy (RUU) at the proximal, middle, and distal ureter.
OBJECTIVE: To assess the morbidity, mortality, and impact on quality of life and renal function after laparoscopic cystectomy and ileal conduit in patients with multiple sclerosis with lower urinary tract symptom refractory to conservative management.
This article interrogates the modes by which cultural constructions of male contraceptive use emerge in Costa Rica by analyzing men's narratives of vasectomy.
BACKGROUND: Optimum management to prevent recurrent kidney stones is uncertain.
PURPOSE: To evaluate the actual impact of testosterone replacement therapy (TRT) on patients with lower urinary tract symptom (LUTS), without benign prostate hyperplasia (BPH) medication.
OBJECTIVE: To study the effect of cigarette smoking on seminal fluid parameters, namely; volume, sperm concentration, and motility, as well as morphology, leukocyte infiltration, among males complaining of infertility.
Penile ossification is very rare, with only a handful of histologically confirmed reported cases.
INTRODUCTION: This review explores the treatment of male chronic pelvic pain syndrome (CPPS) (i.e., chronic prostatitis) through the use of neuromodulation, which is the electrical stimulation of the nervous system.
INTRODUCTION AND HYPOTHESIS: Bladder pain syndrome/interstitial cystitis (BPS/IC) is identified based on subjective symptoms which lead to heterogeneous patient populations.
OBJECTIVES: To evaluate the clinical efficacy of transurethral resection of the prostate on nocturia and sleep disorders in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
Many surgical options exist for women with stress urinary incontinence (SUI).
PURPOSE: To develop a patient-based educational video to address the information needs of women considering sacral nerve stimulation (SNS) for overactive bladder (OAB.)
BACKGROUND: Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition leading to deficient cortisol with an incidence of 1/16,000.
OBJECTIVES: To compare effects of tadalafil on ejaculatory and orgasmic function in patients presenting with erectile dysfunction (ED).
INTRODUCTION: Inflammation is postulated to link obesity and benign prostatic hyperplasia (BPH).
Herein, we report an unusual case of a 78-year-old woman with synchronous presentation of sigmoid cancer and a nonfunctioning primary adrenal cortex carcinoma, who developed superior vena cava syndrome due to metastatic lymphadenopathy from the latter malignancy.
This review highlights the significant advances made in the diagnosis and management of penile cancer.
Background: Testicular cancer patients have an increased risk for cardiovascular disease (CVD), which might be related to the increased prevalence of the metabolic syndrome (MetS) in this group of patients.
We retrospectively evaluated 23 patients who had been administered pirarubicin by intravesical instillation once weekly for 5 weeks, after undergoing surgery for upper urinary tract cancer between May 2003 and October 2008.
BERKELEY, CA (UroToday.com) - Histopathologically, bladder cancer may be divided into urothelial carcinoma (90%) and an assortment of other forms: squamous cell carcinoma (8%), adenocarcinoma (1-2%), and small cell carcinoma of the bladder (0.5–0.7%).
One third of patients with metastatic renal cell carcinoma (RCC) suffer from bone metastases.
BACKGROUND: Urinary tract infection (UTI) is one of the most common infectious diseases at the community level.
Introduction: Renal pseudotumors simulate malignancy but they are, in fact, comprised of normal renal tissue.
BERKELEY, CA USA (Press Release) (PRWEB) - April 24, 2013 -
UroToday inaugurates their second of three comprehensive collaborations on the use of urinary catheters. The latest area, launching this week, is about intermittent catheterization (IC)
Introduction: Metastatic castrate-resistant prostate cancer (mCRPC) is the second deadliest cancer in men.
SAN DIEGO, CA USA (UroToday.com) - Presented by E. David Crawford, MD,1 Adam S. Kibel, MD,2 and Neal D.Shore, MD, FAC 3 at the American Urological Association (AUA) Annual Meeting - May 4 - 8, 2013 - San Diego Convention Center - San Diego, California USA
This position statement has been formulated by nurses from the United Kingdom Oncology Nursing Society (UKONS) to provide guidance on the provision of nurse-led chemotherapy review clinics for adult patients.
BJUI Mini Reviews - Prostate angiosarcoma: Is there any association with previous radiation therapy?
BERKELEY, CA (UroToday.com) - For the current review a literature search was carried out using Pubmed, EmBase, and Cochrane databases.
BJUI Mini Reviews - Current role of diethylstilbestrol in the management of advanced prostate cancer
BERKELEY, CA (UroToday.com) - The aim of this review was to describe the most recent data from contemporary clinical trials of diethylstilbestrol ( DES) to better determine its current role in advanced prostate cancer treatment as new hormonal therapies emerge.
Capsaicin as an inducer of damage-associated molecular patterns (DAMPs) of immunogenic cell death (ICD) in human bladder cancer cells - Abstract
Few conventional cytotoxic anticancer therapeutics induce immunogenic cell death (ICD).
MTHFR C677T and A1298C polymorphisms were associated with bladder cancer risk and disease progression: A meta-analysis - Abstract
Epidemiological studies have investigated that functional polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene may play an essential role in bladder carcinogenesis, but the association between these single-nucleotide polymorphisms in the MTHFR gene and the susceptibility of bladder ...
Pubertal screening and treatment for varicocele do not improve chance of paternity as adult - Abstract
PURPOSE: We investigated the eventual positive effects of early screening and treatment for varicocele in pubertal boys without symptoms to determine their chance of paternity later in life.
Is there an outcome difference between posterior urethral valves diagnosed prenatally and postnatally at the time of antenatal screening? - Abstract
PURPOSE: Posterior urethral valves (PUV) diagnosed during childhood have classically been associated with a better outcome than antenatally diagnosed PUV.
BJUI Mini Reviews - Current status of robot-assisted partial nephrectomy
BERKELEY, CA (UroToday.com) - Partial nephrectomy has shown both improved overall patient survival and more effective preservation of renal function, when compared with radical nephrectomy.
Flexible ureterorenoscopy: Tips and tricks - Abstract
With advancement in technology, improvement in endoscope and ancillary equipment, more complex procedures can be performed using flexible ureterorenoscopy.
Downstream complications following urinary diversion - Abstract
INTRODUCTION: Surveillance following urinary diversion should be tailored to capture complications downstream from the initial reconstruction.
Postoperative outcomes after continent versus incontinent urinary diversion at the time of pelvic exenteration for gynecologic malignancies - Abstract
OBJECTIVE: To compare outcomes of patients undergoing continent or incontinent urinary diversion after pelvic exenteration for gynecologic malignancies.
Preoperative factors influencing postoperative results after vasovasostomy - Abstract
PURPOSE: The purpose of this study is to evaluate the preoperative factors that influenced postoperative sperm concentration after vasovasostomy.
Advances in surgical treatment of male infertility - Abstract
A male factor is the only cause of infertility in 30% to 40% of couples.
Outcomes and safety of retrograde intra-renal surgery for renal stones less than 2 cm in size - Abstract
BACKGROUND: Retrograde intra-renal surgery (RIRS) has been used to remove stones of less than 2 cm in the kidney.
Retrograde approach to a diverticular kidney stone through a vesicoureteral Cohen's reimplantation: A novel surgical technique - Abstract
Cohen's technique is the standard treatment of vesicoureteral reflux in children.
Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men - Abstract
INTRODUCTION: Obesity and inactivity are associated with erectile dysfunction and hypogonadism.
Managing endocrine dysfunction following blast injury to the male external genitalia - Abstract
Blast injury to the external genitalia is associated with considerable morbidity, including the risk of primary hypogonadism due to insufficient testosterone.
Seminal cytokines: Is quantification useful in urogenital disorders? - Abstract
Cytokines are cellular messengers which play a key role in many biological conditions such as immune defence and reproduction.
Occupational causes of male infertility - Abstract
PURPOSE OF REVIEW: To highlight and discuss the new evidence on occupational and environmental risk to male reproductive function.
Surgical management for Peyronie's disease - Abstract
Peyronie's disease is a common debilitating condition for both men and their partners that results in penile deformity and compromises sexual functioning.
AUA 2013 - Podcast: Intralesional therapy with collagenase clostridium histolyticum (CCH), a promising, non-surgical, minimally-invasive option for the treatment of Peyronie's disease
SAN DIEGO, CA USA (UroToday.com) - In this podcast, Dr. Wayne J. G. Hellstrom from Tulane University School of Medicine in New Orleans gives a summary of some of the key points and discusses results from the Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies (IMPRESS) I ...
Periurethral fibrosis secondary to prostatic inflammation causing lower urinary tract symptoms: A prospective cohort study - Abstract
OBJECTIVE: To investigate the role periurethral fibrosis secondary to chronic prostatic inflammation as a potential contributing factor to the etiology of lower urinary tract symptoms (LUTS) in male patients.
Semen quality and associated reproductive indicators in middle-aged males: The role of non-malignant prostate conditions and genital tract inflammation - Abstract
PURPOSE: To compare the associations between non-malignant prostate conditions, genital tract inflammation, and reproductive function in middle-aged men.
Estrogen and progesterone receptors in patients with bladder pain syndrome - Abstract
OBJECTIVE: Analyze if bladder mucosa of patients with bladder pain syndrome (BPS) have more estrogen receptor (ER) and progesterone receptor (PR) than the normal population.
Improvement by the phytotherapeutic agent Eviprostat® of detrusor overactivity, down-regulation of pharmacological receptors and urinary cytokines in rats with cyclophosphamide-induced cystitis, ...
BERKELEY, CA (UroToday.com) - Interstitial cystitis (IC) is a chronic, abacterial, inflammatory disease of the bladder characterized by urinary frequency, urgency, and suprapubic pain associated with bladder filling and relieved by voiding.
Correlation between overactive bladder symptoms and quality of life in Japanese male patients: Focus on nocturia - Abstract
OBJECTIVE: To elucidate the effects of nocturia, one of the most bothersome of symptoms, on health-related quality of life (QOL), we examined the correlation between nocturia-specific QOL and other lower urinary tract symptoms (LUTS).
Survey on lower urinary tract symptoms and sleep disorders in patients treated at urology departments - Abstract
OBJECTIVES: This study examined the association between sleep disorders and lower urinary tract symptoms in patients who had visited urology departments.
An extracorporeal biofeedback device, used in pelvic-floor muscle training, to treat female stress urinary incontinence, "Beyond the Abstract," by Ha Na Lee, MD
BERKELEY, CA (UroToday.com) - Several methods have been used to treat stress urinary incontinence (SUI) in women, from employing a vaginal sensor for pelvic floor muscle exercise to performing general anesthesia for any type of surgery.
Sonographic evaluation of the levator ani muscle in women with stress urinary incontinence - Abstract
Three-dimensional sonography has been used for about 15 years, not only to examine the female genital organs, but also the lower urinary tract and pelvic floor.
Impact of overactive bladder treatment on the quality of life of patients over 60 with associated pathologies - Abstract
OBJECTIVES: To study the impact of treatments prescribed in usual practice to control Overactive Bladder (OAB) on health-related quality of life (HRQoL) of patients with associated pathologies.
Association between gestational diabetes mellitus and subsequent overactive bladder among premenopausal female twins - Abstract
OBJECTIVE: To investigate the association between a history of gestational diabetes mellitus (GDM) and overactive bladder (OAB) in women of premenopausal age.
Pelvic floor muscle training for prevention and treatment of urinary and fecal incontinence in antenatal and postnatal women: A short version Cochrane Review - Abstract
BACKGROUND: Pelvic floor muscle training (PFMT) is commonly recommended during pregnancy and after birth both for prevention and the treatment of incontinence.
A quality of life survey of individuals with urinary incontinence who visit a self-help website: Implications for those seeking healthcare information - Abstract
Urinary Incontinence (UI) affects 200 million people worldwide with annual direct costs in the US alone estimated at $16.3 billion.
Initial and subsequent success with PDE5 inhibitor treatment for erectile dysfunction: Results of a pooled analysis of a large integrated clinical trial database, "Beyond the Abstract," by Angelina ...
BERKELEY, CA (UroToday.com) - Erectile dysfunction (ED) affects a majority of men by the time they reach their 60s.[1]
Avanafil for the treatment of erectile dysfunction: Initial data and clinical key properties - Abstract
Orally active, selective inhibitors of phosphodiesterase type 5 (PDE 5, cyclic GMP PDE), such as sildenafil, tadalafil and vardenafil, are currently the first-choice treatment options for the clinical management of erectile dysfunction (ED) of various etiologies and severities.
BJUI Mini Reviews - Chronic urinary retention in men: How we define it, and how does it affect treatment outcome
BERKELEY, CA (UroToday.com) - Urinary retention describes a bladder that does not empty completely or does not empty at all.
Treatment of lower urinary tract symptoms: Agents for intraprostatic injection - Abstract
When the currently available pharmacotherapeutic principles used for treatment of male lower urinary tract symptoms (LUTS) fail, transurethral resection of the prostate still remains the widely applied gold-standard therapy, since the majority of minimally invasive therapies have not achieved the ...
Treatment with docetaxel and cisplatin in advanced adrenocortical carcinoma, a phase II study - Abstract
Background: Adrenocortical carcinoma (ACC) is a rare disease with a poor response to chemotherapy.
Surgery for adrenocortical carcinoma in the Netherlands: Analysis of national cancer registry data - Abstract
OBJECTIVE: Adrenocortical carcinoma (ACC) is a rare disease with an estimated incidence of 1-2 cases per 1 million inhabitants.
A case report of primary lymphoma presenting as cancer of the glans penis, "Beyond the Abstract," by Konstantinos Stamatiou and Nikolaos Pierris
BERKELEY, CA (UroToday.com) - Malignant tumors of the penis are generally uncommon. The most common type, squamous cell carcinoma, accounts for less than 1% of all malignancies in men in the USA and for 0.1% of cancer deaths.
High CRP values predict poor survival in patients with penile cancer - Abstract
BACKGROUND: High levels of circulating C-reactive protein (CRP) have recently been linked to poor clinical outcome in various malignancies.
Disappearance of a major thrombus in the brachiocephalic vein without anticoagulant therapy in a patient with seminoma: A case report - Abstract
This is the first case report describing brachiocephalic vein thrombosis without compression by a metastatic tumour during chemotherapy for testicular cancer.
International geographic correlation study of the prevalence of disorders of male reproductive health - Abstract
STUDY QUESTION: Is there evidence at the population level of associations between different male genital disorders, outside Scandinavian countries?
A population-based study of tumours of the renal pelvis and ureter: Incidence, aetiology and histopathological findings - Abstract
Objective: Carcinoma of the renal pelvis and ureter are unusual tumours and our limited knowledge comes mainly from case reports and small series from large academic hospitals, as a rule without histopathological review.
The treatment of recurrent urothelial tumors of the upper urinary system and at urostomy site following radical cystectomy with intraureteral Bacillus Calmette-Guérin and cryotherapy - Abstract
Urinary bladder carcinoma is the second most common cancer of the urinary system.
Follow-up after radical cystectomy based on patterns of tumour recurrence and its risk factors - Abstract
CONTEXT: Following cystectomy, approximately 50% of patients will present tumour recurrence.
Bladder cancer in individuals with spinal cord injuries - Abstract
Study design: Prospective scoping review.
The role of surgery for metastatic renal cell carcinoma in the era of targeted therapies - Abstract
PURPOSE: With the emergence of targeted therapies, the indications of cytoreductive nephrectomy have to be redefined.
An evidence-based guide to the selection of sequential therapies in metastatic renal cell carcinoma - Abstract
Targeted therapies have introduced a paradigm shift in the management of metastatic renal cell carcinoma.
Increasing prevalence of ciprofloxacin resistance in extended-spectrum-β-lactamase-producing Escherichia coli urinary isolates - Abstract
PURPOSE: To describe the incidence and drug susceptibility profiles of uropathogenic extended-spectrum-β-lactamase-producing Escherichia coli (ESBL-EC) during a 10-year period and to identify differences in resistance patterns between urological and non-urological ESBL-EC isolates.
Analysis of the spectrum and antibiotic resistance of uropathogens in vitro: Results based on a retrospective study from a tertiary hospital - Abstract
BACKGROUND: Antibiotic resistance of uropathogens in urinary tract infections (UTIs) is increasing worldwide.
Comparison of symptom management strategies for pain, erectile dysfunction, and depression in patients receiving chronic hemodialysis: A cluster randomized effectiveness trial - Abstract
BACKGROUND AND OBJECTIVES: Pain, erectile dysfunction (ED), and depression are common yet frequently untreated in chronic hemodialysis patients.
Contrast-enhanced ultrasound assessment of complex cystic lesions in renal transplant recipients with acquired cystic kidney disease: Preliminary experience - Abstract
We prospectively studied the potential value of contrast-enhanced ultrasound (CEUS) to characterize complex acquired cystic kidney disease (ACKD) or suspected solid renal masses, avoiding the risk of inducing acute kidney injury in 138 renal transplant recipients by contrast-enhanced computed ...
Annapolis/Glen Burnie Maryland urology group of ten is recruiting additional urologists with fellowship training in pediatric urology and female urology/urodynamics
ANNAPOLIS, MD USA - April 19, 2013 - Well-established, physician-owned urology practice is recruiting urologists with fellowship training in pediatric urology and female urology/urodynamics.
Challenges facing academic urology training programs: An impending crisis - Abstract
Objective: To determine the most pressing issues facing academic urology training centers. The supply of urologists per capita in the United States continues to decrease. Stricter resident requirements, restriction of resident duty hours, and a Graduate Medical Education (GME) funding cap on ...
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History of Indwelling Catheters - Bard
For 106 years C. R. Bard, Inc. has maintained its dedication to creating innovative products and services for health-care providers and patients worldwide. Through its strong traditions of quality, integrity, service and innovation, Bard serves as a leading developer, manufacturer and ...
Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) - Abstract
BACKGROUND: Androgen receptor (AR) signalling remains critically important in metastatic castration-resistant prostate cancer (mCRPC) as confirmed by recent phase III trials, showing a survival advantage for abiraterone acetate and enzalutamide (MDV3100).
Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer - Abstract
PURPOSE: As part of the ENTHUSE (Endothelin A Use) program, the efficacy and safety of zibotentan (ZD4054), an oral specific endothelin A receptor antagonist, has been investigated in combination with docetaxel in patients with metastatic castration-resistant prostate cancer (CRPC).
AUA 2013 - Poster: Treatment practice patterns in metastatic castration-resistant prostate cancer (mCRPC) patients prior to receiving sipuleucel-T: Data from PROCEED
SAN DIEGO, CA USA (UroToday.com) - Presented by Matthew R. Cooperberg, MD,1 Oliver Sartor, MD,2 Christopher Pieczonka, MD,3 Raoul S. Concepcion, MD, FACS,4 Vahan Kassabian, MD,5 Ronald Tutrone, MD, FACS, CPI,6 James Bailen, MD,7 Neal Shore, MD, FACS,8 Lawrence Karsh, MD, FACS,9 Bernard Hertzman, MD, ...
AUA 2013 - Poster: Safety and changes in laboratory parameters associated with sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC): Phase 2 ProACT study
SAN DIEGO, CA USA (UroToday.com) - Presented by Thomas Gardner,1 Daniel Petrylak,2 John Corman,3 Simon Hail,4 Ralph Weinstein,5 Robert Sims,6 Todd DeVries,6 and Celestia Higano7 at the American Urological Association (AUA) Annual Meeting - May 4 - 8, 2013 - San Diego Convention Center - San Diego, ...
Evaluation of a nurse-led service for follow up of patients with prostate cancer - Abstract
The incidence of prostate cancer in Scotland continues to grow; men are now living with their disease which can be seen as an increased burden for the health service and in particular the Uro-Oncology team which delivers its treatment and manage its follow up.
Bone micro-environment in prostate cancer: impact, treatment and implications for nursing practice - Abstract
Prostate cancer is a substantial worldwide health care challenge. The disease is associated with detrimental effects on bone remodelling, mediated by the RANK/RANK ligand (RANKL) system.
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