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AUA Highlights - May 23, 2006
AUA 2006 - The Impact of Sex-Hormones on Erectile Dysfunction. Results from the Massachusetts Male Aging Study (MMAS).
Tuesday, 23 May 2006
Abstract 1328 Dr. Varant Kupelian and associates reported at the recent American Urologic Association annual meeting the impact of sex hormones on erectile function as seen in the Massachusetts Male Aging Study.
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AUA 2006 - Recovery of Erectile Function After Nerve-Sparing
Tuesday, 23 May 2006
Abstract 1325 Dr. Andreas Bannowsky and colleagues from Kiel, Germany reported improved recovery of erectile function after nerve-sparing radical prostatectomy with nightly low-dose Sildenafil.
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AUA 2006 - LongTerm Survival of Inflatable Penile Prostheses: Single Surgical Group Experience with 2384 First Time Implants Spanning Two Decades
Tuesday, 23 May 2006
Abstract 1304 Dr. Steven Wilson and associates reported at the American Urologic Association annual meeting the long term results in the largest series of inflatable penile prosthesis [IPP].
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AUA 2006 - The Vattikuti Institute Prostatectomy; A Single Surgeon Experience of 1452 Cases
Tuesday, 23 May 2006
Abstract 1154 Dr Mani Menon reported his most current robotic prostatectomy data involving 1452 patients.
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AUA 2006 - Extraperitoneal Robotic Assisted Radical Prostatectomy
Tuesday, 23 May 2006
Abstract 1153 This report demonstrates that excellent surgical results are possible with rapid OR times in the hands of experienced robotic surgeons.
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AUA 2006 - Perioperative Quality of Care Indicators of Retropubic Laparoscopic and Robotic Prostatectomy: Results from a National, Multicenter, Prospective Cohort
Tuesday, 23 May 2006
Abstract 1151 This report attempted to address the important clinical question of which approach for the man with prostate cancer is best.
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AUA 2006 - Neuroanatomic Maps for Nerve Sparing Robotic Prostatectomy: A Study Describing the Importance of the Neurovascular Plate and its Relationship to the Steps of Surgery.
Tuesday, 23 May 2006
Abstract 1155 The landmark work of Walsh and Donker now more than two decades ago provided the anatomical framework for development of nerve sparing radical prostate surgery.
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AUA 2006 - Sural Nerve Grafting in Robotic laparoscopic Radical Prostatectomy
Tuesday, 23 May 2006
Abstract 1321 The authors report their early experience with robotic laparoscopic placement of sural nerve grafts.
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AUA 2006 Erectile Dysfunction Predicts Extension of Coronary Artery Disease by Angiography in Acute Coronary Syndromes. The Dead Goose Study.
Tuesday, 23 May 2006
Abstract 1340 The authors of this study point out that erectile dysfunction (ED) and coronary artery disease (CAD) frequently coexist.
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AUA 2006 Do Cigarette Smokers with Erectile Dysfunction Benefit from Stopping? A Prospective Study
Tuesday, 23 May 2006
Abstract 1331 Cigarette smoking has been identified as a strong risk factor for erectile dysfunction (ED.)
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AUA 2006 Phosphodiesterase-5 (PDE5) Inhibitor Use in Middle Aged and Older Men with Erectile Dysfunction: Results from the Massachusetts Male Aging Study
Tuesday, 23 May 2006
Abstract 1008 . In 1994, the first report from the Massachusetts Male Aging Study (MMAS) on the prevalence of erectile dysfunction (ED) identified that ED occurs in 52% of men between the ages of 40 and 70 (1).
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AUA 2006 Total Corporal Replacement for Erectile Dysfunction
Tuesday, 23 May 2006
Abstract 1323 Presentations such as extensive penile fibrosis arise in the management of erectile dysfunction in which the loss of erectile tissue function or structure is so severe that medical therapy will be ineffective.
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AUA 2006 Determinants of Success of Bilateral Cavernous Nerve Interposition Grafting During Radical Retropubic Prostatectomy
Tuesday, 23 May 2006
Abstract 1316 The concept of reconstituting the nerve supply to the penis with a structural graft has excited many surgeons in the field of radical prostate surgery as a feasible approach to regain erectile function in their patients after the surgery.
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AUA Podium Session on Stone Disease: Evaluation and Medical Management, May 23, 2006
Monday, 05 June 2006
Margaret Pearle and Dennis Venable moderated this very interesting session. (Abstract numbers follow the comments.)
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AUA 2006 - Prostate Cancer Localized II
Wednesday, 24 May 2006
This session discussed long term outcomes in several techniques for treatment of localized disease and intermediate outcomes in the application of newer techniques.
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AUA 2006 - Prostate Cancer, Robotic Surgery and BPH (Video Session)
Thursday, 25 May 2006
By James Borin, MDThe first prize winning video (V1397) by a multi-institutional collaboration primarily between Cornell and Innsbruck described the evolution of their technique of athermal nerve sparing during robot assisted radical prostatectomy.
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AUA 2006 - Bladder Cancer Detecting And Screening II
Tuesday, 23 May 2006
This session discussed long term outcomes in several techniques for treatment of localized disease and intermediate outcomes in the application of newer techniques.
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AUA 2006 - Adrenal/Kidney/Ureter: Laparoscopy, Ureteroscopy, Instruments and Technology (I).
Tuesday, 23 May 2006
By James Borin, MD This session was devoted primarily to laparoscopic partial nephrectomy (LPN). Inderbir Gill's group at the Cleveland Clinic demonstrated their experience with partial nephrectomies involving tumors that were either intraparenchymal (#872) or hilar (#880).
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AUA 2006 - Adrenal/Kidney/Ureter: Laparoscopy, Ureteroscopy, Instruments & Technology(III)
Tuesday, 23 May 2006
By James Borin, MDThere were several offerings of cryoablation and radiofrequency ablation of small renal lesions in both animal models and humans.
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AUA 2006 - High Expression Levels of Survivin Protein Are An Independent Predictor Of Poor Outcome Among Patients Treated Surgically For Clear Cell Renal Cell Carcinoma
Tuesday, 23 May 2006
Parker, AS et al., Rochester, MN. Abstract 710 Gene array data was utilized to demonstrate that survivin mRNA expression was associated with a worse outcome in conventional RCC.
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AUA 2006 - Are Small Renal Tumors Harmless? Analysis Of Histopathological Features According To Tumor Size In Tumors 4 CM or Less In Diameter
Tuesday, 23 May 2006
Remzi, M., et al, Vienna, Austria Abstract 711 In this study, the authors examined 287 nephrectomy specimens to correlate tumor size with biological potential.
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AUA 2006 - Renal Cell Carcinoma Sub-Typing By Real-Time PCR On Needle Biopsy.
Tuesday, 23 May 2006
Barocas, DA, et al, New York, NY Abstract 724 Ex vivo biopsies were performed on 77 renal masses in 72 patients and evaluated for carbonic anhydrase 9 (CA9), chloride channel (CLCNKB), and alpha-methylacyl coenzyme A racemase (AMACR) through real time PCR techniques.
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AUA 2006 - Cancer-Specific Mortality Is Increased By Erythrocyte Transfusion In Patients Undergoing Surgery For Renal Cell Carcinoma
Tuesday, 23 May 2006
Abstract 733 Routh and colleagues out of Mayo reviewed the records on 2442 renal surgeries for cancer to determine the relationship between perioperative transfusions and cancer specific survival (CSS).
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AUA 2006 - Microvascular Invasion Is Associated With Aggresive Clinicopatholigcal Features And Is An Independent Predictor Of Survival For Patients With Clear Cell Renal Cell Carcinoma
Tuesday, 23 May 2006
Lam, JS, et al., Los Angeles, CA Abstract 741 In this study of 973 patients, microvascular invasion (MVI) was identified in 12.4%.
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AUA 2006 - Resection Of Nodal Disease In Patients With Metastatic Conventional Renal Cell Carcinoma Improves Survival
Tuesday, 23 May 2006
Brassel, S, et al., Houston, TX Abstract 743 Aggressive surgical resection of nodal disease in the setting of cytoreductive surgery for metastatic RCC was evaluated in this study out of M. D. Anderson.
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AUA 2006 - Mononuclear Cell Infiltration In Clear Cell Renal Cell Carcinoma Independently Predicts Patients Survival
Tuesday, 23 May 2006
Webster, WS, et al., Rochester, MN Abstract 746 In this study of 306 patients, primary tumor specimens were characterized for the presence and extent of lymphocyte infiltration as a function of cancer specific survival (CSS).
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AUA 2006 - Fertility in Men with Spinal Cord Injury; New Insights
Tuesday, 23 May 2006
Society for the Study of Male Reproduction by Harris Nagler Saturday, May 20, 2006 Nancy l. Brackett, PhD., HCLD Research Associate Professor of Neurological Surgery and Urology University Of Miami In the United States, 80% of new injuries occur to males. 62% are 16-35 years old.
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AUA 2006 - Epididymitis and Other Inflammatory Conditions of the Male Excurrent Ductal System
Tuesday, 23 May 2006
Society for the Study of Male Reproduction by Harris Nagler Saturday, May 20, 2006 Dr. Peter Chan, Director of Male Reproductive Medicine, McGill University discussed epididymitis and other inflammatory conditions in the male excurrent ductal system.
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AUA 2006 - Ejaculatory Duct Obstruction: Which Are The Best Techniques To Diagnosis And Treat?
Tuesday, 23 May 2006
Society for the Study of Male Reproduction by Harris Nagler Saturday, May 20, 2006 Paul Turek, Associate Professor of Urology from the University of California, San Francisco, presented a review of the current state of our understanding of ejaculatory duct obstruction.
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AUA 2006 - Vasal and Epididymal Reconstructive Surgery in the era of IVF/ICSI
Tuesday, 23 May 2006
Society for the Study of Male Reproduction by Harris Nagler Saturday, May 20, 2006 Anthony J. Thomas, MD, Head, section of Male Infertility, Cleveland Clinic discussed Vasal and Epididymal Reconstructive Surgery in the era of IVF/ICSI
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AUA 2006 - The Issue Of Fertility And Fertility Preservation Must Be Discussed Prior To Any Individual Receiving Therapy For A Malignancy
Tuesday, 23 May 2006
Leslie R. Schover, PhD. Parenthood after Chemotherapy Dr Schover, Professor or Behavioral Sciences, MD Anderson Cancer Center presented highlighted the importance of discussing fertility options and the impact of cancer therapy on patients' fertility prior to initiating therapy.
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AUA 2006 - An Update On Superficial Bladder Cancer
Tuesday, 23 May 2006
The report by Herr and Donat [ABST829] affirmed the role of repeat transurethral resection of bladder tumors in the staging of bladder lesions and the information regarding progression of lesions based on the reTUR data.
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AUA 2006 - An Update On Bladder Cancer Basic Research
Tuesday, 23 May 2006
The discussed poster session on bladder cancer research included presentations regarding the role of individual genes in the initiation and progression of bladder cancer, new insights regarding the mechanism of BCG function and novel preclinical studies that may later lead to therapeutic applications.
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AUA 2006 - An Update On Bladder Cancer Detection and Screening
Tuesday, 23 May 2006
This session contained several papers providing a more robust sense of the role of screening and the strengths and limitations of some of the more popular detection methods.
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AUA 2006 - The Cell Of Origin Of Clear Cell Renal Carcinoma - Revisited
Tuesday, 23 May 2006
Tran, MGB et al. United Kingdom Abstract 368 Tran and colleagues use immunohistochemistry for CD 10, N-cadherin, M2PK, CK 19, E-cadherin, and Tamm-Horsefall protein to gain further insight as to the cell of origin for clear cell renal cell carcinoma (ccRCC), which has been proposed to originate from the proximal tubule cells of the nephron.
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AUA 2006 - Rare Expression Or Mutation Of C-Kit In Grade 4 Renal Cell Carcinoma With Or Without Sarcomatoid Differentiation
Tuesday, 23 May 2006
Sengupta S, et al., Rochester, MN Abstract 383 Previous studies have suggested that RCC with sarcomatoid differentiation express c-kit, and thus might be responsive to therapy with imatinib (Gleevec™).
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AUA 2006 - PD-1 Expressionby Tumor Infiltrating Lymphocytes Is Associated With Poor Prognosis In Renal Cell Carcinoma Patients
Tuesday, 23 May 2006
PD-1 Expressionby Tumor Infiltrating Lymphocytes Is Associated With Poor Prognosis In Renal Cell Carcinoma Patients Thompson, RH, et al., Rochester, MN
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AUA 2006 - Osteopontin Expressions In Metastatic Renal Cell Carcinoma
Tuesday, 23 May 2006
Carmack AJK, et al., Miami, FL Abstract 392 The expression of osteopontin, a secreted glycoprotein, was examined in both the primary tumor and metastases from RCC.
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AUA 2006 - Immune Mediated Survival Advantage And Primary Tumor Control Of Cryoablation Compared To Nephrectomy In A Murine Model Of Advanced Renal Cancer
Tuesday, 23 May 2006
Hedican, SP, et al., Madison, WI Abstract 404 An interesting study by Hedican and colleagues suggests that energy ablative therapies such as cryoablation may offer more than just local tumor control, by augmenting host immune function, to improve survival.
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AUA 2006 - Prostate Cancer; Advanced Session I
Tuesday, 23 May 2006
A Moderated Poster Session on Prostate Cancer Advanced Disease took place on Monday May 22, 2006 at the annual AUA meeting in Atlanta. Summaries from some of the posters are as follows.
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AUA 2006 - Prostate Cancer; Localized Session I
Tuesday, 23 May 2006
A Discussed Poster Session on Prostate Cancer: Localized Disease took place on Monday May 22, 2006 at the annual AUA meeting in Atlanta. Many interesting posters primarily on outcomes of therapy were presented.
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AUA 2006 - Prostate Cancer Basic Research Session III
Tuesday, 23 May 2006
A Discussed Poster Session on Prostate Cancer Basic Research took place on Monday May 22, 2006 at the annual AUA meeting in Atlanta. Three of the many interesting posters on basic and potential translation science are described herein.
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AUA 2006 - Prostate Cancer; Serum Markers
Tuesday, 23 May 2006
A Moderated Poster Session on Prostate Cancer Serum Markers took place on Monday May 22, 2006 at the annual AUA meeting in Atlanta. Summaries of four of the many interesting posters are described herein.
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AUA 2006 - Society of Urologic Oncology –Perspective
Tuesday, 23 May 2006
At this year's SUO meeting the topic of transitional cell carcinoma was addressed as a translational target and a real day problem. It remains the fourth most common malignancy among Western men with disease prevalence in the United States of approximately 500,000 cases, yet therapeutic approaches to this disease have remained rather static over the past several years.
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AUA 2006 - Epidemiology & Natural History Moderated Poster Session 4
Tuesday, 23 May 2006
A retrospective observational study by Wilson et al, [ABST. 127] described an evaluation of alpha 1-blocker use and the incidence of prostate cancer.
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AUA 2006 - Bladder and Urethra: Anatomy, Physiology and Pharmacology
Tuesday, 23 May 2006
This program of basic research of the bladder and urethra attests to the increasing sophistication of work in this area which may lead to greater insight of the subtle complexity of lower urinary tract function and the identification of novel therapeutic targets for disorders of these organs.
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AUA 2006 - Podium Session 11 – Female Urology (I)
Tuesday, 23 May 2006
This female urology podium session was moderated by Drs. Rodney Appell and Elizabeth Ann Gormley.
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AUA 2006 – Pediatric Update: Moderated Poster Session
Tuesday, 23 May 2006
Pediatrics II Moderated Poster Session May 22, 2006 Atlanta, Georgia, USA The session began with Abstract 566 showing 61 laparoscopic orchiopexies on 46 patients with excellent outcomes comparable if not better than a Fowler-Stephens staged approaches.
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AUA 2006 – Pediatric Poster Session Discussion
Tuesday, 23 May 2006
Pediatrics III Discussed Poster Session May 22, 2006 Atlanta, Georgia, USA The session was moderated by Michael Mitchell, MD and Terry Hensle, MD.
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AUA 2006 - Video Session 4: Stone Disease, Ureter
Tuesday, 23 May 2006
During ureteroscopic holmium laser lithotripsy, proximal migration of fragments and the inability to retrieve or release large stones entrapped within a stone basket can be problematic.
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