Role of MRI in Men on Active Surveillance - Laurence Klotz

November 14, 2017

(Length of Discussion: 33 min)

Tom Keane hosts a discussion with Laurence Klotz on the use of MRI in the detection of significant cancer and the possibility of MRI replacing biopsies in men on active surveillance. Dr. Klotz poses the question, can MRI replace biopsies in men on active surveillance?

Through an overview of clinical trial data on 12 different published studies around this hot topic including the Active Surveillance Magnetic Resonance Imaging Study (ASIST) trial, which hypothesizes that by using only targeted biopsies, significant cancer can be found using fewer cores compared to using systematic biopsies. Dr. Klotz notes that new data continues to come in monthly on this topic, which will help determine the implications of using MRI going forward.

Watch: More From Laurence Klotz on: Active Surveillance: Protecting Patients From Harm

Related Content on the Role of MRI in Men on AS

CUA 2017: Role of MRI in Diagnosing Prostate Cancer

Results of a comparative analysis of magnetic resonance imaging-targeted versus three-dimensional transrectal ultrasound prostate biopsies: Size does matter.

AUA 2017: Best of Tertiary Care Center and Collaborative Research

Role of MRI in low-risk prostate cancer: finding the wolf in sheep's clothing or the sheep in wolf's clothing?


Laurence Klotz, MD is the past Chief of Urology at Sunnybrook Health Sciences Centre and Professor of Surgery at the University of Toronto. He is also Chairman of the World Uro-Oncology Federation and a past president of the Urological Research Society and the Canadian Urological Association. Dr. Klotz was the Founding Editor-in-Chief of  both the Canadian Journal of Urology and the Canadian Urology Association Journal, and is now Editor Emeritus of the CUAJ. He was the founder and is chairman of the Canadian Urology Research Consortium. 

Dr. Klotz obtained his medical degree from the University of Toronto and completed his residency at the University of Toronto Gallie Program in Surgery. Dr. Klotz continued his postgraduate studies with a special fellowship at Memorial Sloan Kettering Cancer Centre in New York in uro-oncology and tumour biology.

Thomas E. Keane, MBBCh, FRCSI, FACS