GU Cancers Symposium 2015 - Prostate Cancer

March 6, 2015

GU Cancers Symposium 2015 - Prostate Cancer

Thomas E. Keane, MD
Professor and Chairman of the Department of Urology
Medical University of South Carolina, Charleston, SC USA


Insights into E3805: The CHAARTED trial - Abstract

GU Cancers Symposium 2015 - AR splice variant 7 (AR-V7) and response to taxanes in men with mCRPC

GU Cancers Symposium 2015 - Bench to bedside: Androgen resistance

Final report of the Intergroup randomized study of combined androgen-deprivation therapy plus radiotherapy versus androgen-deprivation therapy alone in locally advanced prostate cancer

Early evidence of increase in higher-risk prostate cancers from 2011-2013 (press release)

Active surveillance of intermediate-risk prostate cancer associated with decreased survival (press release)

Androgen receptor abnormality may not be associated with primary resistance to taxane chemotherapy (press release)


Thomas E. Keane, MBBCh, FRCSI, FACS specializes in managing prostate, bladder, and renal cancers. An avid researcher, Dr. Keane has served as principal investigator or coinvestigator on more than 20 major clinical and preclinical studies, funded by grants from the National Institutes of Health as well as industry-funded. Much of his work focuses on innovative concepts in translational research, including utilizing human tumor xenografts to investigate the efficacy of new therapies as they relate to GU malignancies with particular reference to cytotoxic agents, sphingolipids, and boron-containing compounds. He holds a U.S. patent for BNCT in prostate cancer and sphingolipid derivatives and their use.

Dr. Keane’s research has led to publication of more than 100 articles peer-reviewed in such journals as Cancer Research, The Journal of Urology, Urologic Oncology, and the Journal of Clinical Investigation. He provides editorial services to publications ranging from Urology to the International Journal of Cancer and is coeditor of the text Glenn’s Urologic Surgery, 6th, 7th, and 8th Edition. He is an accomplished speaker, having delivered many presentations to professional societies and symposia throughout the United States and abroad.