Keane's Corner: From the Editor VL

Discussion on SPARTAN: A Study of Apalutamide in Men with Non-Metastatic Castration-resistant Prostate Cancer - Thomas Keane

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(Length of Discussion 17 min) Dr. Thomas Keane reviews recent groundbreaking data presented at the 2018 American Society of Clinical Oncology Genitourinary (ASCO GU) Cancers Symposium focusing on the much awaiting results of the SPARTAN trial. Dr. Keane started by highlighting the SPARTAN Trial presentation by Dr. Eric Small. A Study of Apalutamide (ARN-509) in Men with Non-Metastatic Castration-r...

News Update: Apalutamide as a Treatment for Non-Metastatic Castration-Resistant Prostate Cancer - Thomas Keane

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(Length of Update: 4 min) As we start a new year, Dr. Thomas Keane provides an update on exciting news in the area of non-metastatic castration-resistant prostate cancer with the FDA granting priority review for apalutamide as a treatment for non-metastatic castration-resistant prostate cancer. Currently, there are no FDA-approved treatments for patients with non-metastatic CRPC. Watch Video from...

Review of SIU-ICUD Joint Consultation on Badder Cancer - Thomas Keane

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Dr. Thomas Keane reviews recent data presented at the SIU-ICUD Joint Consultation on Bladder Cancer 2017 conference focusing on a number of presentation highlights. The main purpose of the meeting was for each of the chapter editors to present work from their groups, specifically providing any significant updates from the 2012 edition. They included the level of evidence and grade of recommendatio...

Prostate Cancer Highlights from SUO 2017 - Thomas Keane

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(Length of Discussion: 25 min) Dr. Thomas Keane reviews recent data presented at the SUO 2017 conference focusing on highlights from the prostate cancer session. He reviews a number of presentations including Prostate Cancer Anxiety in Men Undergoing Active Surveillance (AS), a talk presented by Karim Marzouk, MD, FRCSC. In this analysis, the authors use prospective data from a large institutional...

Bladder Cancer Highlights from SIU 2017 - Thomas Keane

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Dr. Thomas Keane reviews recent data presented at the SIU 2017 conference focusing on urothelial carcinoma. Highlighting a number of presentations, he focuses on Translational Observations from Mutation Profiling of Muscle Invasive Bladder Cancer a presentation by Seth Lerner and details his summary slide with 5 subtypes and proposed paradigm for management. He also discusses another presentation...

Role of MRI in Men on Active Surveillance - Laurence Klotz

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(Length of Discussion: 33 min) Tom Keane hosts a discussion with Laurence Klotz on the use of MRI in the detection of significant cancer and the possibility of MRI replacing biopsies in men on active surveillance. Dr. Klotz poses the question, can MRI replace biopsies in men on active surveillance? Through an overview of clinical trial data on 12 different published studies around this hot topic i...

Discussion on the AQUARiUS and EXCAAPE studies- Thomas Keane

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(Length of discussion ~ 13 minutes) Thomas Keane, MD reviews three state of the art presentations from the 2017 European Society for Medical Oncology (ESMO) meeting. Dr. Keane highlights the AQUARiUS study presented by Antoine Thiery-Vuillemin who overviewed the initial results from this patient reported outcomes (PROs) study among men receiving either abiraterone + prednisone or enzalutamide. The...

ESMO 2017: Prostate Cancer Highlights

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(Length of discussion ~ 36 minutes) Thomas Keane reviews recent data presented at the ESMO 2017 conference focusing on advanced prostate cancer and the addition of abiraterone to androgen deprivation therapy as well as the results of the STAMPEDE and LATITUDE trials. Highlighting a number of presentations, he focuses on one in particular “Adding abiraterone acetate plus prednisone or docetaxel for...

STAMPEDE and LATITUDE Trials: Issues to Consider - Thomas Keane

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Biograhy: Thomas E. Keane Related Content: LATITUDE abstract from ASCO 2017 STAMPEDE abstract from ASCO 2017 STAMPEDE - Clinical Trial Information A Clinical Conversation with Alicia Morgans and Charles Ryan: Considerations of ASCO 2017 LATITUDE and STAMPEDE Crashing into progress: New findings meet old habits

Evolution of the Mesh Problem - Eric Rovner

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Mesh changed the field of Female Pelvic Medicine & Reconstructive Surgery (FPMRS) and continues to change the field - "Evolution" of the Mesh Problem Biographies: Thomas E. Keane Eric S. Rovner, MD Related Content: Short-term complications associated with use of transvaginal mesh