Imaging: Prostate Cancer VL

Results from the Phase 3 SPOTLIGHT Trial of 18F-rhPSMA-7.3 in Recurrent Prostate Cancer - David Schuster

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David Schuster joins Phillip Koo in discussing the results of SPOTLIGHT, a phase 3, prospective, multicenter study assessing the detection rate of 18F-rhPSMA-7.3 PET in patients with suspected prostate cancer recurrence. The single-arm SPOTLIGHT imaging study, conducted in the United States and Europe evaluates the safety and diagnostic performance of 18F-rhPSMA-7.3 PET imaging in men with suspect...

The Impact of Imaging and Therapeutics Advances in Nonmetastatic Castration-Resistant Prostate Cancer - David Penson

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David Penson joins Alicia Morgans to discuss the rapidly changing landscape in prostate cancer, focusing on how imaging and therapeutic advances have disrupted the landscape in the nonmetastatic castration-resistant prostate cancer (CRPC) setting. Dr. Penson highlights advancements in PSMA scanning and how it impacts potential study inclusion criteria. Drs. Morgans and Penson also discuss PSMA PET...

Clinical Trial Equity in Radionuclide Treatment for Prostate Cancer - Joseph Osborne

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Phillip Koo is joined by Joseph Osborne to provide a nuclear radiologist's perspective on the equity in prostate cancer clinical trials. Dr. Osborne focuses his talk on three different aspects of clinical trial equity for prostate cancer: Progress, Evolution, and Goals. He also details the Rad Health Equity Lab, created at Weill Cornell to improve access to radiology and bring awareness to health...

PSMA PET/CT Imaging Indications in Prostate Cancer - Neal Shore & Oliver Sartor

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Philip Koo, Oliver Sartor, and Neal Shore discuss the revolutionary impact of PSMA PET in the detection and management of prostate cancer. The experts explain the approved indications of PSMA PET agents PSMA 11 and PYLARIFY, emphasizing their transformative role in managing high-risk and intermediate-risk prostate cancer patients. Drs. Shore and Sartor detail how these imaging technologies inform...

NCCN Guidelines On PSMA Molecular Imaging - Tanya Dorff

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Alicia Morgans and Tanya Dorff, discuss the updates to the NCCN guidelines since the approval of PSMA PET CT molecular imaging agents. They discuss new guidance based on the FDA-approved indications in the labels for the use of molecular imaging agents for detecting prostate cancer when PSA levels are still relatively low and when PSA levels are rising. Biographies: Tanya B. Dorff, MD., is an asso...

PSMA Imaging - Is Conventional Imaging Obsolete - Steven Rowe

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In this Society of Nuclear Medicine and Molecular Imaging- Special Session during the 2021 LUGPA CME presentations, Dr Steven Rowe discusses a number of different scenarios that we might encounter clinically where conventional imaging is clearly being replaced by PSMA based imaging. In the last part of his talk, Dr. Rowe focuses on some future directions where PSMA PET may have some interesting th...

Understanding Physiological PSMA Biodistribution - Jeremie Calais

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In this educational initiative, focusing on the knowledge of PSMA PET and PSMA theranostics, Jeremie Calais presents on understanding the physiological PSMA biodistribution and the pathological uptake of the use of PSMA for prostate cancer. Independent Medical Education Initiative Supported by Novartis/Adacap and Point Biopharma Biographies: Jeremie Calais, MD, MSc, Director, Clinical Research Pro...

The Use of Imaging for Patient Selection for PSMA Directed Therapies – Jeremie Calais

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Alicia Morgans speaks with Jeremie Calais about the evolving landscape of theranostic and imaging modalities in prostate cancer. The discussion primarily focuses on the role of PSMA PET imaging in patient selection for PSMA-directed therapies like lutetium PSMA. Dr. Calais elaborates on the criteria used in the VISION trial and the complexities surrounding the necessity of targeted imaging for tar...

Developing a Theranostics Program, The Nebraska Cancer Specialists Model - Samuel Mehr

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In a conversation hosted by Phillip Koo, Sam Mehr outlines the intricacies of establishing a theranostics program within a medical oncology practice. Dr. Mehr discusses the "NCS/Nebraska Cancer Specialists model," which aims to offer targeted nuclear therapy through a patient-centered approach. He emphasizes the importance of a multidisciplinary team, including a program director who serves as the...

F-18-Labeled DCFPyL in Patients With Metastatic Prostate Cancer Undergoing Treatment With ADT – Esther Mena Gonzalez

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In this presentation from Esther Mena Gonzalez, she discusses her team’s findings on the role of castration status or hormone-sensitive castrate-resistance data and androgen deprivation therapy (ADT) in the use of 18F DCFPyL PET/CT. She discussed the objective of her study to be to investigate the performance of 18F DCFPyL in her cohort of patients with documented metastatic prostate cancer who we...