Enobosarm in Postmenopausal Women for Stress Urinary Incontinence - Interview with Kenneth Peters

(Length of Discussion: 9 min)

Diane Newman, DNP, FAAN, BCB-PMD interviews Kenneth Peters, MD about the data he presented at the SUFU 2018 meeting on results from the single-arm, open-label Phase 2 clinical trial evaluating enobosarm in postmenopausal women with stress urinary incontinence (SUI).  Enobosarm, which is an oral selective androgen receptor modulator, given as an androgenic agent to modulate the pelvic floor and urinary sphincter for stress urinary incontinence (SUI).  This study is the first clinical trial evaluating an orally-administered selective androgen receptor modulator (SARM) for SUI.  THis data is a proof of concept study but there is currently a national trial taking place, ASTRID (Assessing Enobosarm for Stress Urinary Incontinence Disorder) a placebo controlled trial where a placebo dose of 3mg is being compared to a lower 1mg dose with hopes to have data by the end of the year with hopes to show supportive data in this patient population. 

Biographies: 

Kenneth M. Peters, MD  Professor and Chairman of Urology, Dr. Kenneth Peters is an urologist in Royal Oak, Michigan and is affiliated with Beaumont Hospital-Royal Oak. He received his medical degree from Case Western Reserve University School of Medicine and has been in practice for more than 20 years. Rochester, MI

Diane K. Newman, DNP, FAAN, BCB-PMD

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Kenneth Peters, MD SUFU 2018 presentation: Oral Enobosarm Shows Promising Activity in Post-Menopausal Women with Stress Urinary Incontinence: Results of a Phase 2 Study

New Data Demonstrating Enobosarm’s Potential to Treat Stress Urinary Incontinence -Presented at SUFU 2018

GTx Announces Positive Results from Enobosarm Phase 2 Proof-of-Concept Clinical Trial in Women with Stress Urinary Incontinence

Watch: “Kegels In A Bottle”: Preliminary Results Of A Selective Androgen Receptor Modulator For The Treatment Of SUI - Kenneth M. Peters
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