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- Carissa Chu joins Sam Chang to discuss data on genetic changes and alterations in urothelial carcinoma. The purpose of the study is to characterize human epidermal growth factor receptor 2 (HER2) (ERBB2) and fibroblast growth factor receptor 3 (FGFR3) mutations in a prospectively collected cohort of urothelial cancers. Dr. Chu highlights the key findings from this study. Biographies: Carissa Chu,...
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- Alicia Morgans is joined by Jeannie Hoffman-Censits and Elizabeth Guancial to discuss the challenges women face navigating a bladder cancer diagnosis. In 2022, the American Cancer Society estimates more than 81,000 will be diagnosed with bladder cancer in the United States. Of those, 61,700 will be men, and 19,480 will be women. Drs. Morgans, Hoffman-Censits, and Guancial discuss the importance of...
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- Ashish Kamat and Peter Black delve into a new term, 'BCG-Exposed', in high-risk non-muscle-invasive bladder cancer. Published by the International Bladder Cancer Group, the definition sheds light on this gray area, aiming to enhance clinical trial design and regulatory processes. Dr. Black's publication explores the intricacies of various disease states associated with BCG (Bacillus Calmette-Guéri...
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- In a discussion hosted by Ashish Kamat, Boris Gershman presents his study comparing radical cystectomy and trimodality therapy for muscle-invasive urothelial carcinoma of the bladder. The study aims to fill a significant knowledge gap, as no randomized trials have directly compared these treatments. Using an emulation framework to replicate the UK's SPARE trial, which closed due to low recruitment...
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- Benjamin Miron, a 2021 recent recipient of the Bladder Cancer Advocacy Network's (BCAN) Young Investigator Award joins Alicia Morgans to speak about the Young Investigator Award Program. Dr. Miron speaks on the importance of this program and the opportunity it provides young investigators to jumpstart their careers. This funding Dr. Miron received helped to investigate new biomarkers for bladder c...
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- Ashish Kamat is joined by Bernard Bochner to discuss patient quality of life after a radical cystectomy. Dr. Bochner highlights a number of factors that can be affected by having a radical cystectomy which is a significant surgery. Drs. Kamat and Bochner offer insights on assembling a team to assure the best quality of life for these patients. Biographies: Bernard H. Bochner, MD, FACS, Attending S...
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- Siamak (Sia) Daneshmand joins Ashish Kamat in a discussion on the role of blue-light cystoscopy (BLC) in detecting invasive bladder tumors. Providing background on the beneficial use of BLC in carcinoma in situ (CIS), Dr. Daneshmand highlights the evidence on the potential of finding additional TA tumors with the use of BLC. He showcases data from a BJUI multi-institutional registry publication on...
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- Ashish Kamat and Sarah Psutka, discuss how to optimize radical cystectomy patients long before the patient even enters the operating room. Dr. Psutka touches on the complications of the procedure, as well as ways that we can try to limit those complications. They also discuss risk stratification and additional testing for radical cystectomy candidates. Biographies: Sarah P. Psutka, MD, MSc, Urolog...
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- Ashish Kamat and Molly Ingersoll, discuss mucosal immunity in the bladder with specific reference to gender differences and how that affects biology. Dr. Ingersoll shares how the immune system knows how to kill specific tumor cells, and how those are mechanistically different between sexes. This conversation also addresses the need to form larger collaborative research efforts to really attack the...
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- Urologic Oncologist Phillip Abbosh joins Alicia Morgans discussing the importance of the Bladder Cancer Advocacy Network (BCAN) Young Investigator Awards for early-career investigators to join the bladder cancer scientific community and those thinking about getting their projects and their careers off the ground in bladder cancer. Phillip Abbosh a BCAN YI Award recipient in 2018 shares details of...
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