ASCO GU 2020 VL

The Landscape of Advanced Bladder Cancer: A Review of the Last 30-Years - Cora Sternberg

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Cora Sternberg joins Alicia Morgans at ASCO GU 2020 and discusses the significant advancements in the treatment of advanced bladder cancer looking back over the last 30 years. MVAC was regulatory approved as the first line treatment in metastatic bladder cancer thirty years ago. Cora discusses the recent progress that is offering significant improvements in the overall survival for those patients...

PSMA PET Diagnostic Imaging in the Current Era - Jeremie Calais

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Phillip Koo interviews Jeremie Calais about PSMA PET imaging in patients with localized prostate cancer. Professor Calais discusses the advantages of whole-body PSMA PET imaging in patients with presumed localized cancer, as well as those likely to have extraprostatic disease. The PSMA whole-body imaging modality can be used to identify cancer lesions with high sensitivity in patients. PSMA PET is...

Clinical Trials for Men with Testicular Cancer - Darren Feldman

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Darren Feldman joins Alicia Morgans to discuss clinical trials and the treatment of testicular cancer. Dr. Feldman provides an overview of the TIGER trial, an international randomized, multicenter open-label phase III trial. The study is an international collaboration with European sites. Collaborators on the study include the National Cancer Institute, the European Organization for Research and T...

Active Surveillance for Low-Risk Prostate Cancer - Laurence Klotz and Peter Carroll

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Matt Cooperberg hosts a discussion with Peter Carroll and Laurence Klotz examining their roles in the progress of active surveillance for low-risk prostate cancer and how they incorporate this treatment into clinical practice. They discuss the change in the field from over-detection and overtreatment where radiation and surgery were the primary treatment options to the evolution of active surveill...

AR Indifferent Subtype Tumors in Prostate Cancer - Ana Aparicio

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Ana Aparicio joins Alicia Morgans at ASCO GU 2020 to discuss her work with AR indifferent tumors in the field of prostate cancer. Among the topics discussed, Dr. Aparicio stressed the importance of understanding clinical features and the development of a profile of this AR indifferent subtype in order to allow for easier identification. The two further discuss the research and ongoing clinical tri...

Quality of Life in the Treatment of mHSPC: The STAMPEDE Trial - Hannah Rush

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Hannah Rush joins Alicia Morgans discussing the quality of life outcomes we have seen from patients receiving docetaxel or abiraterone in the STAMPEDE trial. STAMPEDE is a multi-arm, multi-stage trial investigating various therapeutic strategies for the management of locally advanced or metastatic hormone-naïve prostate cancer. In recent years, both docetaxel and abiraterone have been shown to imp...

Phase III Nadofaragene Firadenovec for BCG-Unresponsive Non-Muscle Invasive Bladder Cancer - Joshua J. Meeks

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In this discussion, Josh Meeks joins Alicia Morgans to review the new advances phase III Nadofaragene Firadenovec (Adstiladrin®) trial for BCG unresponsive non-muscle invasive bladder cancer patients. Dr. Meeks details the results of this recently presented trial data and why he believes this is the beginning of the next era in treating these patients. Biographies: Josh J. Meeks, MD, Ph.D., Assist...

Updates on Bladder Cancer Clinical Trials ASCO GU 2020 - Matthew Galsky

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Joining Alicia Morgans is Matt Galsky to discuss the biggest updates in bladder cancer clinical trials. Building off of his overview of IMvigor130, KEYNOTE-361, and JAVELIN Bladder 100, Dr. Galsky provides insight on how he incorporates clinical data into his everyday practice and the direction he believes the field is moving towards in the future. Biographies: Matthew Galsky, MD Director of Genit...

Research and Clinical Practice Strategies Due to the BCG Shortage - Sam S. Chang

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Sam Chang joins Ashish Kamat to discuss strategies for clinical trials and patient selection required in the face of the world-wide shortage of BCG. Biographies: Sam S. Chang, MD, MBA , Patricia and Rodes Hart Endowed Chair of Urologic Surgery Professor Department of Urology at Vanderbilt University Medical Center, Department of Urology Ashish Kamat, MD, MBBS Professor of Urology and Wayne B. Dudd...

Bladder Cancer Research That Impacts Urology Clinical Practice - Josh Meeks

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Joshua Meeks joins Ashish Kamat in discussing the most recent relevant research papers in bladder cancer. Together they explore the publications on checkpoint inhibitors, the use of The Cancer Genome Atlas, Enhanced Recovery after Cystectomy and the impact of blue light flexible cystoscopy with CYSVIEW. Biographies: Josh J. Meeks, MD, Ph.D., Assistant Professor of Urology and Biochemistry and Mole...