Navigating the Adverse Effects of ADT - Neal Shore

(Length of lecture - 19 minutes)

Dr. Neal Shore addresses both the perception and evidence of side effect for patients on androgen deprivation therapy (ADT). There is a growing concern about ADT side effects now that it is being used more in non-metastatic prostate cancer, which is exposing men to ADT for longer periods of time.  Several common adverse effects are known about ADT impacting multiple organ systems including the central nervous system, as well as the hematologic, reproductive, musculoskeletal and endocrine systems. Researchers are also now taking a closer look at the link between ADT and cognitive impairment, particularly dementia. Dr. Shore also discusses studies examining ADT's effect on the metabolic and cardiovascular function of prostate cancer patients.

Related Content on ADT Side Effects:

Watch: Cognitive Function and Hormone Therapy in Advanced Prostate Cancer - Interview with Alicia Morgans

Watch: ADT Impact on Cardiovascular Health - Jehonathan Pinthus

Watch: Bones, Hot Flashes and ADT: Using with Chemotherapy and Timing - Thomas Keane

Clinical trial:Cognitive Effects of Androgen Receptor (AR) Directed Therapies for Advanced Prostate Cancer

Assessment of Cardiovascular Risk With the Use of Androgen Deprivation Therapy for Prostate Cancer: EVERYDAY UROLOGY- Full Text Article


ASCO 2017: Physical and Cognitive Effects of Systemic Therapy in Older Men with Prostate Cancer

Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer - Abstract

Cardiovascular Effects of Androgen Deprivation Therapy for the Treatment of Prostate Cancer

Biography:
Neal Shore, MD, FACS, is an internationally recognized expert in systemic therapies for patients with advanced urologic cancers and innovative therapies to treat patients suffering from prostate enlargement symptoms. Dr. Shore was recently appointed President of the Large Urology Group Practice Association (LUGPA), which seeks to provide urologists with all the tools they need to effectively care for patients.

Dr. Shore is the Medical Director of the Carolina Urologic Research Center. He practices with Atlantic Urology Clinics in Myrtle Beach, South Carolina. Dr. Shore has conducted more than 300 clinical trials, focusing mainly on prostate and bladder disease. Dr. Shore is a Certified Physician Investigator who has numerous publications in peer-reviewed journals and has lectured extensively on the treatment of prostate cancer and prostate enlargement. He serves on several industry advisory boards as well as academic and advocacy networks: including the Society Urologic Oncology Clinical Trials Consortium, Bladder Cancer Advocacy Network,and the Large Urology Group Practice Association.. Dr. Shore is the editor-in-chief of UroToday’s print publication, Everyday Urology- Oncology Insights.
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