Advanced Prostate Cancer VL

3D Prostate Gland Uptake of 18F Choline PET CT - Association with Overall Survival in Patients with Hormone-naive Prostate Cancer - May Sadik

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Dr. May Sadik presents data from the SNMMI meeting highlighting a retrospective study in 45 patients with hormone naïve prostate cancer. The objective was to develop a completely automated method to quantify prostate gland update of 18F-choline in PET/CT images. The hope is that these preliminary data will lead to a better understanding of the relationship between this measure, the clinical data a...

Neoadjuvant Therapy Prior to Prostatectomy - Mary-Ellen Taplin

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In this conversation, Mary-Ellen Taplin reviews her work from the past nine years in the area of neoadjuvanct therapies prior to prostatectomy. Mary-Ellen discusses how research on combining systematic therapy with prostatectomy when next generation androgen-AR axis inhibitors were developed have now lead to the launch of a large, international phase 3 trial. Biographies: Mary-Ellen Taplin, MD Cha...

Life-Prolonging Treatments for Advanced Prostate Cancer - Maha Hussain

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Maha Hussain joins Alicia Morgans and reflects on the journey she has traveled from 1983 when prostate cancer was viewed as a disease exclusive to older men, where there were no real biomarkers and a lack of understanding for the spectrum of the disease. Maha delivers one of the pivotal talks at the PCF 25th Annual retreat and here we gain her perspective on the evolving landscape of life-prolongi...

Disparities in Prostate Cancer Clinical Trial Participation - Hala Borno

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Hala Borno and Charles Ryan discuss the ongoing and increasing problems in the enrollment of clinical trials in oncology. Hala describes her goals in this area and her passion for uncovering differences that lead to inequities. Hala is currently developing a patient facing tool called Trial Library, that is a clinical trial online matching website developed based on patient-prompted conversations...

18F Fluorocholine PET-Whole Body MR in the Staging of High Risk Prostate Cancer - Ur Metser

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Ur Metser a study that was conducted to determine whether integrated 18F-fluorocholine (FCH) PET whole-body MRI (PET/WBMRI) depicts lymph node and distant metastases in patients with high-risk prostate cancer more frequently than does conventional staging. Biography: Ur Metser, MD, FRCPC, Joint Department of Medical Imaging, the University of Toronto Related Content: 18F-Fluorocholine PET Whole-Bo...

68Ga PSMA 11 PET MRI in Intermediate and High Risk Prostate Cancer - Claudia Zacharias

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Claudia Zacharias presents Gallium 6 PSMA-11 PET/MR Imaging in Patients with Newly Diagnosed Intermediate- or High-Risk Prostate Cancer, a pilot study evaluating the detection rate for the initial diagnosis of prostate cancer and the metastatic spread for patients in the intermediate and high-risk prostate cancer risk category using 68 Ga-PSMA-11 PET/MR. She reviews the potential role of 68 Ga-PSM...

A Review of Imaging Modalities in Prostate Cancer - Peter Pinto

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(Length of Interview: 17 min) Peter Pinto highlights the paradigm shift to the use of new imaging technology for a more accurate diagnosis of prostate cancer. Targeted MRI/Ultrasound (MR/US) guided biopsy vs TRUS biopsy, full body imaging options such as PET, and Axumin® (fluciclovine F 18) as a staging tool, with mention of metabolic and focal imaging are part of this comprehensive interview. As...

Effectiveness of Radical Prostatectomy with Adjuvant Radiotherapy versus Radiotherapy Plus ADT for Men with Advanced Prostate Cancer - Tom Keane

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(Length of video: 9 min) Tom Keane reviews an article entitled, “Comparative Effectiveness of Radical Prostatectomy with Adjuvant Radiotherapy versus Radiotherapy Plus Androgen Deprivation Therapy for Men with Advanced Prostate Cancer”. Men with locally advanced prostate cancer or regionally advanced prostate cancer treated initially with radical prostatectomy plus radiation had a lower risk of pr...

A Review on Practice Informing Prostate Cancer Study Results - Christopher Sweeney

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(Length of Conversation: 18 min) Christopher Sweeney and Alicia Morgans review practice informing data released at the ESMO 2018 meeting from the GETUG 12, ERA 223, and STAMPEDE studies. Biographies: Christopher Sweeney, MBBS, Professor of Medicine, Harvard Medical School, Medical Oncologist, Dana-Farber Cancer Institute Alicia Morgans, MD, MPH Related Content: 12-Year Follow-Up of GETUG-12, A Pha...

Targeting Treatment to Subtypes in Prostate Cancer - Misha Beltran

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Misha Beltran and Alicia Morgans discuss treatment selection for patients with unique molecular subtypes. They discuss the use of ADT in this patient population as well as chemotherapy. Interestingly, they highlight the shared alteration and learnings from the study of small cell lung cancer. Biographies: Himisha Beltran, MD, Medical Oncologist, Dana Farber Cancer Institute, Harvard Medical School...