Advanced Prostate Cancer VL

What Is the Evidence of Systemic Therapies (Alone or in Combination With MDT) in Oligometastatic mHSPC? APCCC 2022 Presentation - Mary Ellen Taplin

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At the 2022 Advanced Prostate Cancer Consensus Conference (APCCC), Mary Ellen Taplin presents the role of systemic therapy in the treatment of patients with oligometastatic and oligoprogressive prostate cancer. Biographies: Mary Ellen Taplin, MD, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA Related Content: APCCC 2022: What Is the Evidence of Systemic Therapies (Alone or in Com...

Impact of Histology Variants (Ductal/Intraductal/Cribriform) on Treatment Recommendation Presentation - Declan Murphy

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At the 2022 Advanced Prostate Cancer Consensus Conference, Declan Murphy presents the impact of histology variants (ductal/intraductal/cribriform) on treatment recommendations. Biographies: Declan Murphy, MB, BCh, BaO, FRACS, FRCS Urol, Professor, Urologist & Director of GU Oncology, Peter MacCallum Cancer Centre, Associate Editor, BJUI, Honorary Clinical Professor, The University of Melbourne Rel...

Efficacy and Safety of 177Lu-PNT2002 PSMA Therapy in Metastatic Castration-Resistant Prostate Cancer in the SPLASH - Neil Fleshner

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Charles Ryan is joined by Neil Fleshner to discuss the efficacy and safety of radioligand 177Lu-PNT2002 in PSMA-positive patients with metastatic castration-resistant prostate cancer (mCRPC) who progressed after treatment with androgen receptor axis-targeted therapy (ARAT) in the SPLASH trial. Drs. Ryan and Fleshner start by discussing the issue of dosimetry and why it was important for the FDA to...

Update on Immune Checkpoint Inhibitors APCCC 2022 Presentation - Emmanuel Antonarakis

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At the 2022 Advanced Prostate Cancer Consensus Conference (APCCC), Emmanuel Antonarakis provided an update on the role of immune checkpoint inhibitors in the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC). Biographies: Emmanuel Antonarakis, MD, Clark Endowed Professor of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota Rela...

Aggressive Variant Prostate Cancer: Definition, Diagnosis, Treatment APCCC 2022 Presentation - Eric Small

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Eric Small presents a discussion on primary small cell prostate cancer and therapeutic approaches to consider in aggressive variant prostate cancer (AVPC) and small cell neuroendocrine prostate cancer (t-SCNC) patients. Biographies: Eric Small, MD, Doris and Donald Fisher Distinguished Professorship in Clinical Cancer Research; Stanford W. Ascherman and Norman R. Ascherman Endowed Chair, UCSF, Pro...

Importance of Lifestyle and Prevention of Complications in Advanced Prostate Cancer: How to Take Care of Muscle Strength? APCCC 2022 Presentation - Heather Cheng

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At the 2022 Advanced Prostate Cancer Consensus Conference (APCCC) Hybrid Meeting, Heather Cheng presents the importance of lifestyle and prevention of complications in advanced prostate cancer, focusing on how we should take care of our patient’s muscle strength. Biographies: Heather H. Cheng, MD, PhD, Director, Seattle Cancer Care Alliance Prostate Cancer Genetics Clinic, Division of Medical Onco...

Smarter Screening In Prostate Cancer - Sigrid Carlsson

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Sigrid Carlsson joins Phillip Koo in a discussion on Smart Screening in Prostate Cancer, a session being highlighted at the upcoming 6th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer taking place virtually September 22-24. The pair discuss challenges with screening today that require clinicians to be smarter about screening including the risk of overdiagnosis, incorporating...

Emerging Therapies and Therapeutic Targets in Prostate Cancer - Mark Rubin

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Mark Rubin joins Alicia Morgans to discuss emerging therapies and emerging therapeutic targets in prostate cancer. Topics covered include types of resistance, epigenetic therapies, and EZH2 inhibitors. Dr. Rubin also shares his thoughts on how he sees molecular pathology impacting cancer care in the next decade. Biographies: Mark A. Rubin, MD, Professor, Principal Investigator, and Director of Dep...

Immunotherapy and PARP Inhibitors in Biochemical Recurrent Prostate Cancer - Alexandra Sokolova

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Alexandra Sokolova joins Alicia Morgans to discuss her work on biochemical recurrent prostate cancer. Dr. Sokolova and her team at OHSU hypothesize that a combination of durvalumab and olaparib will result in a deeper remission, delay the need for ADT, and improve the quality of life for patients who have a shorter PSA doubling time and a higher risk of developing metastasis. Biographies: Alexandr...

How Do the Data from the PEACE-1, ARASENS and ENZAMET Studies Inform Clinical Practice? - Karim Fizazi

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Karim Fizazi and Alicia Morgans discuss the latest ENZAMET updates shared at ASCO 2022. Dr. Fizazi considers the data from the ENZAMET study within the context of findings from the PEACE-1 AND ARASENS trials. In considering the data from these studies, Dr. Fizazi concludes by sharing his treatment recommendations for patients with de novo high volume MET versus de novo low volume MET, as well as t...
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