Peyronie's Disease (PD) Articles

BERKELEY, CA (UroToday.com) - Owing mainly to an incomplete understanding of the exact pathogenesis, the optimal management of Peyronie’s disease (PD) remains a clinical dilemma, particularly the nonsurgical approach.

Erectile dysfunction (ED) is a common condition that is characterized by progressive corporal smooth muscle fibrosis. There is currently no widely accepted methods to characterize the extent and severity of penile fibrosis.

Numerous treatments have been proposed for Peyronie's disease (PD). As the evidence base has expanded, the field of operative and non-operative options for patients has narrowed. Collagenase clostridium hystolyticum (CCH) injection now comprises the medical option, and surgical possibilities entail penile plication, plaque incision/excision and grafting, and prosthesis implantation.

Peyronie's disease (PD) is an idiopathic chronic fibrotic disease that causes a penile curvature (PC), subsequent erectile dysfunction (ED) and impaired sexual intercourse in patients. As of yet, there are no reliable non-surgical treatment options available.

The need for repeat penile plication (PP) for persistent penile deformity has previously been associated with (I) poor initial erectile response to intracavernosal injection (ICI), (II) an inadequate number of corrective sutures, and (III) a lack of sutures along the proximal shaft of the penis.

To describe a novel, tunica-sparing surgical technique-extra-tunical grafting (ETG)-for the treatment of penile indent and hourglass (HG) deformities and to describe patient-reported outcomes after the ETG procedure.

Limited data are available on how partners of men with Peyronie's disease (PD) are affected by the disease. We sought to characterize PD patients whose curvatures result in pain for their partners during penetrative intercourse.