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BERKELEY, CA (UroToday.com) - Owing mainly to an incomplete understanding of the exact pathogenesis, the optimal management of Peyronie’s disease (PD) remains a clinical dilemma, particularly the nonsurgical approach.

Erectile dysfunction (ED) is a common condition that is characterized by progressive corporal smooth muscle fibrosis. There is currently no widely accepted methods to characterize the extent and severity of penile fibrosis.

Numerous treatments have been proposed for Peyronie's disease (PD). As the evidence base has expanded, the field of operative and non-operative options for patients has narrowed. Collagenase clostridium hystolyticum (CCH) injection now comprises the medical option, and surgical possibilities entail penile plication, plaque incision/excision and grafting, and prosthesis implantation.

To describe a novel, tunica-sparing surgical technique-extra-tunical grafting (ETG)-for the treatment of penile indent and hourglass (HG) deformities and to describe patient-reported outcomes after the ETG procedure.

Limited data are available on how partners of men with Peyronie's disease (PD) are affected by the disease. We sought to characterize PD patients whose curvatures result in pain for their partners during penetrative intercourse.