BERKELEY, CA (UroToday.com) - Prostate cancer is the most common non-skin cancer and the second most common cause of cancer death in men.[1] For the majority of men with incident prostate cancer (approximately 85%), the disease is diagnosed as localized (T1-2). When the disease is organ confined the definitive treatment options commonly include: radical prostatectomy, external beam radiation therapy (EBRT), and brachytherapy.