Multiple Myeloma Articles


  • A patient with Multiple myeloma and Renal cell carcinoma.

    The coexistence of two malignancies is rarely seen. A little association between hematologic malignancies especially multiple myeloma and renal cell carcinoma has been reported in the recent past. Several case series revealed a bidirectional association between these two malignancies which may be due to the common risk factors, similar cytokine growth requirements and clinical presentation.

    Published April 12, 2016
  • Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone.

    The bone marrow is a favored site for a number of cancers, including the hematological malignancy multiple myeloma, and metastasis of breast and prostate cancer. This specialized microenvironment is highly supportive, not only for tumor growth and survival but also for the development of an associated destructive cancer-induced bone disease.

    Published August 4, 2016
  • Comprehensive geriatric assessment and decision-making in older men with incurable but manageable (chronic) cancer.

    In older cancer patients, treatment decision-making is often complex. A comprehensive geriatric assessment (CGA) is an established tool used in geriatric medicine to identify unmet need requiring intervention.

    Published August 27, 2018
  • Denosumab for the treatment of bone disease in solid tumors and multiple myeloma.

    Bone is a common site for malignant involvement, either as a site of metastasis, especially in breast or prostate cancer, or as a defining characteristic of the disease, as in multiple myeloma. Bone disease is a major source of morbidity, and half of patients with bone involvement develop skeletal-related events such as pathological fractures or cord compression requiring surgery and/or radiation.

    Published October 24, 2017
  • Immune Cells Act as Promising Targets for the Treatment of Bone Metastasis.

    Bone metastasis is a common complication of certain types of cancer, and unfortunately, it is still incurable to date. Immune system is a major defence against tumor cells and bone metastasis. However, the immunodeficient mouse models are widely used in most researches of bone metastasis, thereby excluding the regulatory roles of the immune system in bone metastasis.

    Published June 12, 2017