Molecular Pathogenesis Articles


  • Diagnosis and Management of Hereditary Renal Cell Cancer.

    Renal cell cancer (RCC) is the common denominator for a heterogeneous group of diseases. The subclassification of these tumours is based on histological type and molecular pathogenesis. Insight into molecular pathogenesis has led to the development of targeted systemic therapies.

    Published April 20, 2016
  • Molecular pathogenesis of human prostate basal cell hyperplasia.

    Understanding the molecular pathogenesis of distinct phenotypes in human benign prostatic hyperplasia (BPH) is essential to improving therapeutic intervention. Current therapies target smooth muscle and luminal epithelia for relief of lower urinary tract symptoms (LUTS) due to BPH, but basal cell hyperplasia (BCH) remains untargeted.

    Published August 13, 2017