Hypothalamus Articles


  • Androgen deficiency in males.

    The terms androgen deficiency, testosterone-deficiency syndrome and male hypogonadism have been used interchangeably. It is a clinical condition affecting a significant number of men in the US and worldwide, and is under-recognized and under-treated.

    Published March 3, 2019
  • Sex differences in the effects of androgens acting in the central nervous system on metabolism.

    One of the most sexually dimorphic aspects of metabolic regulation is the bidirectional modulation of glucose and energy homeostasis by testosterone in males and females. Testosterone deficiency predisposes men to metabolic dysfunction, with excess adiposity, insulin resistance, and type 2 diabetes, whereas androgen excess predisposes women to insulin resistance, adiposity, and type 2 diabetes.

    Published February 13, 2017
  • The impact of androgen actions in neurons on metabolic health and disease.

    The male hormone testosterone exerts different effects on glucose and energy homeostasis in males and females. Testosterone deficiency predisposes males to visceral obesity, insulin resistance and type 2 diabetes.

    Published September 10, 2017

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