Cigarette Smoke Articles


  • Cigarette smoking promotes bladder cancer via increased platelet-activating factor.

    Cigarette smoking is the number one risk factor for bladder cancer development and epidemiological data suggest that nearly half of all bladder cancer patients have a history of smoking. In addition to stimulating the growth of a primary tumor, it has been shown that there is a correlation between smoking and tumor metastasis.

    Published February 20, 2019
  • Puberty exposure to cigarette smoke extract impairs adult spermatogenesis in the mouse.

    Epidemiological studies suggested that exposure to cigarette smoke early in life is associated with long-term health risks. Using a nuclear factor erythroid 2-related factor 2 (Nrf2) knockout (KO) mouse model, we found the sperm concentration and sperm motility were significantly lower in mice exposed to cigarette smoke extract (CSE) beginning at 4 weeks of age compared to 8 week-old mice.

    Published March 17, 2019